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Arifine 10 Tablet is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, it also helps in managing mental depression along with other antidepressant medicines. It contains Aripiprazole, which stabilizes and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the positive symptoms like hallucinations, misbeliefs, and unfriendly characteristics of schizophrenia. It improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, it improves mood swings, depression, and other psychotic problems. Some people may experience drowsiness, headache, tiredness, akathisia (an inability to sit still), difficulty sleeping, lightheadedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

ARIPIPRAZOLE-10MG

Manufacturer/Marketer :

Icon Life Sciences

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Arifine 10 Tablet

Arifine 10 Tablet is an oral prescription medicine used to treat conditions that affect how you think, feel, or behave. Doctors commonly prescribe it to help manage schizophrenia, bipolar disorder, and major depression. It works by balancing certain chemical messengers in the brain to improve mood, thoughts, and behaviour.

For this medicine to work effectively, it is important to take it consistently every single day at the same time. You can take it with or without food. Along with taking your medicine, maintaining a stable daily routine, eating a balanced diet, and getting regular sleep can help you achieve the best results.

While taking Arifine 10 Tablet , some people may experience mild side effects like drowsiness, headache, or nausea. However, you must contact your doctor immediately if you notice more serious signs, such as uncontrollable muscle movements, severe stiffness, a high fever, or sudden changes in your mood.

Do not take this if you have had a severe allergic reaction to it in the past. Elderly patients with dementia-related psychosis should not take this medicine due to serious health risks. Before starting, tell your doctor if you have a history of heart problems, diabetes, seizures, or a low white blood cell count.

This medicine can interact with alcohol, smoking, and other drugs, such as certain blood pressure medicines or anti-seizure drugs, which can change how it works or increase side effects. If you are pregnant, planning to become pregnant, breastfeeding, or an older adult, talk to your doctor or pharmacist to ensure this medicine is safe for you.

Uses of Arifine 10 Tablet

Arifine 10 Tablet is used to manage schizophrenia, bipolar disorder, and major depression. The detailed uses of Arifine 10 Tablet are as follows:

  • Schizophrenia: Arifine 10 Tablet helps reduce symptoms like hearing voices, seeing things that are not there (hallucinations), and feeling unusually suspicious of others.
  • Bipolar I Disorder: It helps control manic episodes, which are periods of extreme excitement, overactivity, irritability, and racing thoughts.
  • Major Depressive Disorder: It is used as an add-on treatment alongside standard antidepressants when those medicines do not fully relieve your symptoms.
  • Irritability associated with autistic disorder: It helps manage severe mood swings, temper tantrums and self-injurious behaviours in children and teenagers.
  • Tourette's disorder: It helps reduce the frequency and severity of uncontrollable physical movements and vocal sounds (tics).
     

Key Benefits

Arifine 10 Tablet helps improve mental health by balancing chemical messengers in the brain and supporting emotional stability. It can help manage symptoms of certain mental health conditions, improving daily functioning and overall quality of life.

  • Helps Improve Mood and Emotional Wellbeing: By restoring the balance of brain chemicals, Arifine 10 Tablet helps reduce symptoms such as persistent sadness, anxiety, irritability, and emotional distress, supporting a more stable mood.
  • Supports Control of Mood Swings: For individuals with conditions involving significant mood fluctuations, Arifine 10 Tablet helps reduce the frequency and severity of extreme mood changes, promoting greater emotional stability and day-to-day functioning.
  • Enhances Daily Functioning: By improving mood, reducing anxiety, and supporting clearer thinking, Arifine 10 Tablet helps individuals participate more comfortably in work, social interactions, and everyday activities. When used as an add-on treatment for depression, it may provide additional symptom relief when antidepressant therapy alone is not sufficient.
     
Side effects of Arifine 10 Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Do pelvic floor exercises (Kegel exercises) to gain more control over urinary sphincters (muscles used to control flow of urine out of the bladder).
  • Drink fluids only at certain times to control when you will urinate.
  • If you feel frequent urge to urinate or have problems starting to urinate or if your urine stream is weak or starts and stops, or feel pain in your genitals, lower abdomen or lower back, consult your doctor.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

  • Arifine 10 Tablet can be taken with or without food, as advised by the doctor.
  • It is usually taken once daily or as prescribed by your doctor.
  • Swallow Arifine 10 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Arifine 10 Tablet Works

Arifine 10 Tablet works by acting on specific chemical messengers in your brain, primarily dopamine and serotonin. These chemicals play a vital role in regulating your mood, thoughts, and behaviours. Unlike some older medicines that completely block these chemicals, Arifine 10 Tablet acts like a thermostat. If the levels of dopamine in certain parts of the brain are too high, it helps lower them. If the levels are too low, it helps boost them. This stabilising effect helps reduce hallucinations, calm hyperactive states, and improve overall mood and motivation.
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Alcohol

Unsafe

Avoid alcohol consumption while taking Arifine 10 Tablet , as it may increase the risk of side effects such as dizziness, drowsiness, or difficulty concentrating.

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Pregnancy

Unsafe

Arifine 10 Tablet is a Category C pregnancy drug. It is not recommended for use during pregnancy, especially in the third trimester, as it may cause extrapyramidal and/or withdrawal symptoms in newborn babies.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Arifine 10 Tablet , as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Unsafe

Arifine 10 Tablet may cause dizziness or vision problems, such as blurred vision. Therefore, avoid driving if you feel dizzy or have vision disturbances after taking Arifine 10 Tablet .

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Liver

Caution

Take Arifine 10 Tablet with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Arifine 10 Tablet with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Arifine 10 Tablet is not recommended for children below 13 years due to the increased risk of adverse effects. However, please consult a doctor before giving Arifine 10 Tablet to children.

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Heart

Caution

Exercise caution while taking Arifine 10 Tablet if you have any cardiac problems due to the risk of hypotension and irregular heartbeat.

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Geriatrics

Consult your doctor

Limited information available for use of Arifine 10 Tablet in elderly patients. Please consult your doctor.

What if I have taken an overdose of Arifine 10 Tablet

If you take too much of this medicine, seek immediate medical attention or call your local poison control centre. Symptoms of an overdose may include severe sleepiness, a fast heart rate, vomiting, and tremors.

Diet & Lifestyle Advise

  • Stay hydrated: This medicine can make it harder for your body to cool down. Drink plenty of water and avoid becoming overheated, especially during hot weather or intense exercise.
  • Monitor your weight and blood sugar: Eat a balanced diet rich in vegetables, lean proteins, and whole grains to help manage potential weight gain and blood sugar changes.
  • Avoid alcohol: Drinking alcohol can worsen side effects like sleepiness, dizziness, and confusion.
  • Stand up slowly: To prevent dizziness or fainting, take your time when rising from a sitting or lying position.
     
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Have a query?

How Soon It Starts Working

  • The time required for Arifine 10 Tablet to start to work: The time required for Arifine 10 Tablet to show its action is not clinically established.
  • The time for which the effects of Arifine 10 Tablet last: The duration of action for Arifine 10 Tablet is not clinically established.

What if you forget to take Arifine 10 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Arifine 10 Tablet tablets at room temperature, between 20°C to 25°C (68°F to 77°F).

Drug Warnings

  • Pay close attention to any sudden changes in mood, behaviour, or thoughts of self-harm, especially during the first few weeks of starting this medicine.
  • Avoid driving, operating machinery, or performing dangerous tasks until you know how this medicine affects your alertness.
  • Tell your dentist or surgeon that you are taking Arifine 10 Tablet before undergoing any medical procedures.
  • Avoid hot tubs, saunas, and prolonged exposure to direct sunlight, as this medicine can affect your body's temperature regulation.
  • If you have diabetes, check your blood sugar levels regularly, as this medicine can cause blood sugar levels to rise.
     

Drug-Drug Interactions

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Drug-Drug Interactions

  • Blood pressure medicines: Combining Arifine 10 Tablet with drugs that lower blood pressure may increase the risk of dizziness or fainting when standing up.
  • Sedatives and sleep aids: Taking this medicine with other drugs that cause drowsiness, such as allergy medicines, sleep aids, or strong pain relievers, can cause severe sleepiness.
  • Liver enzyme inhibitors or inducers: Certain antifungals (like ketoconazole) or antidepressants (like fluoxetine) can raise levels of Arifine 10 Tablet in your body, while some anti-seizure medicines (like carbamazepine) can lower them. Your doctor may need to adjust your dose.


Drug-Food Interactions

  • Grapefruit: Grapefruit and grapefruit juice may interfere with how your body processes this medicine, potentially increasing side effects.


Drug-Disease Interactions

  • Dementia: Elderly patients with dementia-related psychosis must not take this medicine, as it increases the risk of stroke and death.
  • Seizure disorders: Use with caution if you have a history of seizures, as this medicine may increase the likelihood of having one.
  • Diabetes: This medicine can raise blood sugar levels, requiring close monitoring if you have diabetes or a family history of the condition.
     
BaclofenHydrocodone
Severe

Drug-Drug Interactions

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How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet can enhance the sedative effects of Pentazocine on the central nervous system which can lead to side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is a possible interaction between Pentazocine and Arifine 10 Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
BaclofenHydrocodone
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Hydrocodone may increase sedation and respiratory distress (fluid collects in the air sacs of the lungs)

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet can be used with Hydrocodone if prescribed by the doctor. Co-administration of these medications may cause dizziness, drowsiness, difficulty in concentrating, and impaired judgment. Do not stop any medication without doctor's consultation.
BaclofenDezocine
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Dezocine can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet can be used with Dezocine if prescribed by the doctor. These may cause dizziness, drowsiness, palpitations, or chest discomfort. Do not stop taking the medications without a doctor's advice.
BaclofenMethadone
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Methadone may cause serious side effects such as central nervous system depression can lead to serious side effects including respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet can be used with Methadone if prescribed by the doctor. Inform the prescriber if you are taking these two medicines, the doctor may prescribe alternate medicines a dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue any medications without consulting a doctor.
BaclofenHydromorphone
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Hydromorphone may increase the central nervous system and can lead to serious side effects including respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet can be used with Hydromorphone if prescribed by the doctor. Inform the prescriber if you are taking these two medicines, the doctor may prescribe alternate medicines or a dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue any medications without consulting a doctor.
BaclofenPethidine
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet can enhance the sedative effects of Meperidine on the central nervous system which can lead to serious side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Taking Pethidine with Arifine 10 Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed and motor coordination. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Tramadol may significantly lead to adverse effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although taking Arifine 10 Tablet and tramadol together can result in an interaction, it can be taken on a doctor's advice. If you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Butorphanol can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Arifine 10 Tablet and Butorphanol, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like dizziness, shortness of breath, palpitations, or chest discomfort, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Morphine may increase the risk or severity of side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Taking Arifine 10 Tablet with Morphine together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you notice any sudden dizziness, lightheadedness, severe headache, shortness of breath, chest pain or tightness, or weakness. Do not stop using any medications without consulting a doctor.
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet can enhance the effects of Nalbuphine, which depresses the central nervous system and can lead to serious side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is a possible interaction between Arifine 10 Tablet and Nalbuphine, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling tired, dizzy, or having trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS]

FAQs

Arifine 10 Tablet is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, it also helps in managing mental depression along with other antidepressant medicines.
Arifine 10 Tablet contains Aripiprazole, an antipsychotic that works by inhibiting the dopamine receptors in the brain and preventing their overactivity. Thereby, helps in controlling the positive symptoms (such as hallucinations, misbeliefs and unfriendliness) of schizophrenia. Also, Arifine 10 Tablet improves the activity of dopamine receptors in other areas of the brain and helps in controlling negative symptoms (such as social isolation, lack of emotion, poor attention and memory loss) of schizophrenia. Therefore, Arifine 10 Tablet improves behaviour and thoughts, enhances social life, and helps one comfortably perform daily activities.
No, you are not recommended to take Arifine 10 Tablet with ibuprofen as co-administration of these medicines may increase the risk of fits and increase the levels of Arifine 10 Tablet in the blood, leading to increased adverse effects. However, please consult a doctor before taking Arifine 10 Tablet with other medicines.
Arifine 10 Tablet is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people, as it may cause severe adverse effects, including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Arifine 10 Tablet .
Yes, Arifine 10 Tablet may cause high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Arifine 10 Tablet , and you should inform your doctor if you have diabetes before starting Arifine 10 Tablet . However, if you experience dry mouth, increased thirst or urination, or a fruity breath odour, please consult a doctor, as these may be signs of high blood sugar.
No, you are not recommended to stop taking Arifine 10 Tablet without consulting your doctor, as it may worsen the condition or cause recurring symptoms. Therefore, take Arifine 10 Tablet for as long as your doctor has prescribed it. If you experience any difficulty while taking Arifine 10 Tablet , please consult your doctor so that the dose can be gradually reduced.
Yes, Arifine 10 Tablet is a mood stabiliser. It helps calm the mood and treats mood-related problems.
Arifine 10 Tablet may cause priapism (prolonged and painful erection) in some people. Please consult the doctor if you have any concerns.
Elderly patients more than 65 years old with dementia-related psychosis treated with Arifine 10 Tablet can be at an increased risk of death. Increased risk of suicidal thinking and behaviour changes has been observed in children, adolescents, and young adults taking Arifine 10 Tablet , so close monitoring for worsening and the emergence of suicidal thoughts and behaviours is required.
Avoid intake of grapefruit juice with Arifine 10 Tablet as it may reduce the effect of Arifine 10 Tablet . Also, avoid alcohol consumption with Arifine 10 Tablet as it may increase the risk of side effects such as dizziness, drowsiness or difficulty concentrating. Do not drive if you feel dizzy or have vision disturbances after taking Arifine 10 Tablet .
Consult the doctor if you are diabetic, as Arifine 10 Tablet may cause high blood sugar levels. Regular monitoring of blood glucose levels is advised.
Arifine 10 Tablet may cause side effects like drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Arifine 10 Tablet do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.
Some people may experience weight gain while taking this medicine. Regular exercise and a balanced diet can help manage this. Talk to your doctor if you are concerned about weight changes.
It is highly recommended to avoid alcohol while taking this medicine. Alcohol can increase drowsiness, dizziness, and the risk of other side effects. Talk to your doctor if you have questions.
This depends on how the medicine affects you. If it makes you feel sleepy, your doctor may suggest taking it at bedtime. If it makes you feel restless or alert, taking it in the morning may be better. Talk to your doctor for advice.
Taking this medicine during the third trimester of pregnancy may cause side effects in the newborn baby. If you are pregnant or planning to become pregnant, talk to your doctor to weigh the risks and benefits.
An inability to sit still or a feeling of inner restlessness can sometimes occur. Do not stop the medicine; instead, talk to your doctor, who may adjust your dose or suggest a way to manage this.

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Country of origin

INDIA

Manufacturer/Marketer address

Icon Life Sciences, Div. Of Mesmer Pharmaceuticals, No.202/6, Lane In.30, Phase-II, IDA, Cherlapally, Hyderabad, 500 051 AP
Other Info - ARI0160
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