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Apretop 125 mg/80 mg Capsule Kit 1's belongs to a class of drugs called anti-emetics. It is used in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines) in adults and adolescents aged 12 years and above. Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.
Apretop 125 mg/80 mg Capsule Kit 1's contains Aprepitant, a neurokinin 1 (NK1) receptor antagonist which works by blocking the neurokinin-1 receptor (causes the feeling of sickness) present in the vomiting centre in the brain. Thus, it helps prevent nausea and vomiting.
Take Apretop 125 mg/80 mg Capsule Kit 1's as prescribed. You are recommended to take Apretop 125 mg/80 mg Capsule Kit 1's for as long as your doctor has advised it. In some cases, Apretop 125 mg/80 mg Capsule Kit 1's may cause common side effects such as headache, constipation, loss of appetite, tiredness, indigestion, and hiccups. Most of these side effects do not require medical attention and gradually resolve over time. However, consult your doctor immediately if the side effects persist or worsen.
Please tell your doctor if you are allergic to Apretop 125 mg/80 mg Capsule Kit 1's or any other medicines. Apretop 125 mg/80 mg Capsule Kit 1's is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Apretop 125 mg/80 mg Capsule Kit 1's. Avoid driving or operating machinery if you feel dizzy or sleepy after taking Apretop 125 mg/80 mg Capsule Kit 1's. If you are taking other prescription or non-prescription medicines, inform your doctor before taking Apretop 125 mg/80 mg Capsule Kit 1's.
Apretop 125 mg/80 mg Capsule Kit 1's is used in the prevention of nausea and vomiting caused by cancer chemotherapy. The detailed uses of Apretop 125 mg/80 mg Capsule Kit 1's are as follows:
Apretop 125 mg/80 mg Capsule Kit 1's contains Aprepitant, an anti-emetic (a drug used to treat nausea and vomiting) that works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it is used in combination with other medicines to prevent nausea and vomiting caused by anti-cancer medicines in adults and adolescents from the age of 12 years.
Consult your doctor
The interaction of alcohol with Apretop 125 mg/80 mg Capsule Kit 1's is unknown. If you have any concerns regarding this, please discuss them with your doctor.
Consult your doctor
If you are pregnant or planning pregnancy, inform your doctor before taking Apretop 125 mg/80 mg Capsule Kit 1's. Your doctor may prescribe this medicine only if clearly needed.
Consult your doctor
It is unknown whether Aprepitant is excreted in breast milk. Hence, if you are a nursing mother, inform your doctor before taking Apretop 125 mg/80 mg Capsule Kit 1's.
Caution
Apretop 125 mg/80 mg Capsule Kit 1's may cause dizziness or drowsiness in some people. Hence, do not drive or operate machinery if you feel dizzy or drowsy after taking Apretop 125 mg/80 mg Capsule Kit 1's.
Caution
If you have liver disease, inform your doctor before taking Apretop 125 mg/80 mg Capsule Kit 1's. Your doctor may monitor your liver condition.
Consult your doctor
If you have any kidney problems, inform your doctor before taking Apretop 125 mg/80 mg Capsule Kit 1's.
Unsafe
Apretop 125 mg/80 mg Capsule Kit 1's is not recommended for children below 12 years of age.
Consult your doctor
Please consult your doctor before receiving Apretop 125 mg/80 mg Capsule Kit 1's if you have pre-existing heart problems. Your doctor will prescribe Apretop 125 mg/80 mg Capsule Kit 1's if the benefits outweigh the risks.
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Limited information available about the use of Apretop 125 mg/80 mg Capsule Kit 1's in geriatric patients. Please consult your physician.
Have a query?
Please tell your doctor if you are allergic to Apretop 125 mg/80 mg Capsule Kit 1's or any other medicines. Apretop 125 mg/80 mg Capsule Kit 1's is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Apretop 125 mg/80 mg Capsule Kit 1's. Avoid driving or operating machinery if you feel dizzy or sleepy after taking Apretop 125 mg/80 mg Capsule Kit 1's. If you are taking any other prescription or non-prescription medicines, inform your doctor before taking Apretop 125 mg/80 mg Capsule Kit 1's.
Drug-Drug Interactions: Avoid taking Apretop 125 mg/80 mg Capsule Kit 1's with antipsychotics (pimozide), antiallergic drugs (terfenadine, astemizole), and gastroprokinetic agents (cisapride). Apretop 125 mg/80 mg Capsule Kit 1's may interact with immunosuppressants (tacrolimus, everolimus, cyclosporine, sirolimus), pain killers (fentanyl, alfentanil), the medicine used to treat an irregular heartbeat (quinidine), anticancer medicines (etoposide, vinorelbine, irinotecan, ifosfamide), blood thinners (acenocoumarol, warfarin), antibiotics (clarithromycin, telithromycin, rifampicin), anticonvulsants (phenytoin, carbamazepine), medicines used to produce calmness or help you sleep (triazolam, phenobarbital, midazolam), antifungals (ketoconazole, voriconazole, posaconazole, itraconazole), antidepressant (nefazodone), corticosteroids (dexamethasone, methylprednisolone), anti-anxiety medicines (alprazolam), antidiabetic agent (tolbutamide) and medicines used to treat migraines and HIV infections.
Drug-Food Interactions: Apretop 125 mg/80 mg Capsule Kit 1's may interact with St. John’s Wort (herbal preparation used to treat depression).
Drug-Disease Interactions: If you have liver disease, inform your doctor before taking Apretop 125 mg/80 mg Capsule Kit 1's.
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Apretop 125 mg/80 mg Capsule Kit 1's is used to treat Chemotherapy-induced nausea and vomiting.
Apretop 125 mg/80 mg Capsule Kit 1's works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it is used in combination with other medicines to prevent nausea and vomiting caused by anti-cancer medicines in adults and adolescents from the age of 12 years.
You are not recommended to take erythromycin with Apretop 125 mg/80 mg Capsule Kit 1's as it may increase the blood levels and effects of Apretop 125 mg/80 mg Capsule Kit 1's. Contact your doctor if your condition changes or experience side effects such as diarrhoea, constipation, nausea, or loss of appetite. However, please consult your doctor before taking other medicines with Apretop 125 mg/80 mg Capsule Kit 1's.
You are advised not to take hormonal birth control medicines such as birth control pills, implants, skin patches, and certain Intrauterine devices (IUDs) as they may not work properly when taken together with Apretop 125 mg/80 mg Capsule Kit 1's. Therefore, you are recommended to use another or additional non-hormonal form of birth control method during treatment with Apretop 125 mg/80 mg Capsule Kit 1's and for up to 2 months after using Apretop 125 mg/80 mg Capsule Kit 1's.
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