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More about the Product

Composition :

MEXILETINE-50MG

Manufacturer/Marketer :

RMPL Pharma Llp

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Apremex 50 Capsule 10's

Apremex 50 Capsule 10's is an oral prescription medicine used to treat serious, life-threatening irregular heartbeats, specifically ventricular arrhythmias. Its primary medical purpose is to help stabilise your heart's rhythm, so it beats normally and pumps blood efficiently. By regulating these electrical signals, it helps prevent dangerous cardiac events.

To get the best results, you must take this medicine consistently at the exact times prescribed by your doctor. It is typically taken with food, milk, or an antacid to help prevent stomach upset and promote smooth digestion. Alongside taking your medicine, your doctor may suggest heart-healthy dietary changes to support your cardiovascular system.

While taking Apremex 50 Capsule 10's, you might experience mild side effects like heartburn, nausea, or mild dizziness. However, if you experience serious symptoms such as severe chest pain, a worsening irregular heartbeat, or signs of liver damage, you must contact your doctor immediately. Regular monitoring of your health is a key part of your treatment plan.

Before starting this treatment, tell your healthcare provider if you have any pre-existing health conditions. Do not take this if you have certain severe heart conditions, such as cardiogenic shock or specific types of heart block, unless you have a working pacemaker. Your doctor will evaluate your heart health to ensure this medicine is safe for you.

This medicine can interact with other substances, including other heart medications, caffeine, and tobacco smoke. If you are pregnant, breastfeeding, or an older adult, discuss the potential risks and benefits of taking Apremex 50 Capsule 10's with your doctor. Always keep a complete list of everything you take and share it with your healthcare team.

Uses of Apremex 50 Capsule 10's

Apremex 50 Capsule 10's is used to treat serious, life-threatening irregular heartbeats, specifically ventricular arrhythmias. The detailed uses of Apremex 50 Capsule 10's are as follows:

  • Serious irregular heartbeats (ventricular arrhythmias): Apremex 50 Capsule 10's helps control life-threatening rapid or irregular heartbeats in the lower chambers of the heart, allowing it to pump blood safely and effectively throughout the body.

Key Benefits

Apremex 50 Capsule 10's helps maintain a steady and regular heart rhythm, improving heart function and reducing symptoms associated with abnormal heartbeats. With regular use as prescribed, it supports cardiovascular health and helps you carry out your daily activities with greater confidence.

  • Maintains a Regular Heart Rhythm: By helping stabilise the heart's electrical activity, this medicine helps prevent abnormal heart rhythms and supports efficient heart function.
  • Reduces Symptoms of Irregular Heartbeats: This medicine helps reduce palpitations, lightheadedness, dizziness, and other symptoms associated with heart rhythm disorders, improving daily comfort.
  • Supports Better Quality of Life: By promoting a stable heart rhythm, this medicine helps reduce physical stress on the heart, improves confidence during everyday activities, and supports long-term cardiovascular health.

Directions for Use

  • Apremex 50 Capsule 10's can be taken with food to prevent stomach upset or as advised by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Apremex 50 Capsule 10's as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Apremex 50 Capsule 10's Works

The heart relies on precise electrical signals to contract and pump blood. Sometimes, these electrical pathways become overactive or erratic, causing the heart to beat too quickly or irregularly. Apremex 50 Capsule 10's contains mexiletine, which works by blocking specific sodium channels in your heart's muscle cells. By slowing down the flow of sodium, it dampens the abnormal electrical impulses that cause rapid, dangerous heartbeats, helping your heart return to a calm, steady rhythm.
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol while taking Apremex 50 Capsule 10's as it may worsen dizziness or drowsiness.

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Pregnancy

Consult your doctor

Limited data are available on the effect of Apremex 50 Capsule 10's in pregnancy. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Apremex 50 Capsule 10's.

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Breast Feeding

Consult your doctor

If you are breastfeeding, please inform your doctor before taking Apremex 50 Capsule 10's. Mexiletine may be excreted in breast milk. Therefore, if your doctor prescribes Apremex 50 Capsule 10's, you will be advised to choose an alternate method of feeding your baby.

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Driving

Unsafe

Apremex 50 Capsule 10's may cause dizziness, drowsiness or blurred vision in some people. Therefore, avoid driving if you experience such side effects after taking Apremex 50 Capsule 10's.

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Liver

Caution

Apremex 50 Capsule 10's should be used with caution in patients with mild to moderate liver dysfunction and is not recommended for patients with severe liver disease. Therefore, inform your doctor if you have any liver problems before taking Apremex 50 Capsule 10's.

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Kidney

Unsafe

Apremex 50 Capsule 10's is not recommended for patients with severe kidney disease. Therefore, inform your doctor if you have any kidney disease before taking Apremex 50 Capsule 10's.

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Children

Unsafe

Apremex 50 Capsule 10's is not recommended for children and adolescents below 18 years of age.

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Heart

Safe if prescribed

Apremex 50 Capsule 10's is used for serious heart rhythm disorders but should be avoided without prescription. It can alter cardiac electrical activity and require close monitoring due to potential side effects.

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Geriatrics

Safe if prescribed

Apremex 50 Capsule 10's should be avoided in geriatric patients unless prescribed. Older adults may be more sensitive to its cardiac and nervous system effects, requiring close medical supervision.

What if I have taken an overdose of Apremex 50 Capsule 10's

If you suspect an overdose, seek emergency medical attention immediately. Symptoms of an overdose can include severe dizziness, confusion, seizures, or a dangerously slow heartbeat.

Diet & Lifestyle Advise

  • Limit caffeine intake: Apremex 50 Capsule 10's slows down how your body processes caffeine. Consuming coffee, tea, energy drinks, or chocolate can cause caffeine to build up in your system, leading to nervousness, insomnia, or a rapid heart rate.
  • Maintain a consistent sodium diet: Sudden changes in the amount of salt you eat can affect how your kidneys clear this medicine from your body. Avoid starting a strict low-sodium diet or suddenly increasing your salt intake without discussing it with your doctor.
  • Avoid smoking: Tobacco smoke can speed up how quickly your body eliminates this medicine, making it less effective. If you start or stop smoking while taking Apremex 50 Capsule 10's, tell your doctor immediately, as your dose may need to be adjusted.
  • Stay hydrated: Drink an adequate amount of water daily unless your doctor has advised you to restrict fluids due to a heart condition.
health query

Have a query?

How Soon It Starts Working

  • The time required for Apremex 50 Capsule 10's to start to work: Apremex 50 Capsule 10's ideally shows its action within 1 hour after administration.
  • The time for which the effects of Apremex 50 Capsule 10's last: The effect of Apremex 50 Capsule 10's lasts for 10 to 12 hours.

What if you forget to take Apremex 50 Capsule 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a forgotten one. Talk to your doctor or pharmacist if you are unsure what to do.

Storage

• Store Apremex 50 Capsule 10's at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Attend all follow-up appointments: Your doctor will need to monitor your heart's electrical activity regularly with electrocardiograms (ECGs) and perform routine blood tests to check your liver function.
  • Stand up slowly: This medicine can cause dizziness, especially when rising from a sitting or lying position. Get up slowly to prevent falls.
  • Report new symptoms immediately: If you notice your irregular heartbeat getting worse, or if you feel new chest discomfort, contact your doctor right away.
  • Inform other healthcare providers: Always tell any doctor, dentist, or pharmacist you visit that you are taking Apremex 50 Capsule 10's, especially before undergoing any surgical procedures.
  • Do not stop abruptly: Stopping this medicine suddenly can cause your abnormal heart rhythms to return. Always consult your doctor before making any changes.

verifiedApollotooltip
  • Other heart rhythm medicines: Taking this with other antiarrhythmic drugs may increase the risk of side effects or further disrupt your heart rhythm.
  • Liver enzyme-altering drugs: Medications like rifampin or cimetidine can change how your body processes Apremex 50 Capsule 10's, potentially making it less effective or raising its levels to unsafe amounts.
  • Urinary acidifiers or alkalinisers: Medicines that significantly change the acidity of your urine can alter how your kidneys eliminate this drug.

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verifiedApollotooltip
  • Caffeine: This medicine decreases the breakdown of caffeine in your body, which can amplify caffeine-related side effects like anxiety or a rapid heartbeat.
  • Extreme changes in dietary salt: A sudden increase or decrease in your daily sodium intake can change how your kidneys handle this medicine, affecting its concentration in your blood.

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Habit Forming

No

Therapeutic Class

[ANTIARRHYTHMICS]

FAQs

Apremex 50 Capsule 10's is used to treat life-threatening arrhythmias (irregular heartbeats) such as ventricular arrhythmia. Arrhythmia is a condition in which your heart beats irregularly, too fast, or too slow.
Apremex 50 Capsule 10's contains Mexiletine which works by blocking certain electrical signals in the heart. Thereby, it helps to stabilize the heart rhythm.
Apremex 50 Capsule 10's may cause blurred or double vision in some people. Therefore, drive only if your vision is clear after taking Apremex 50 Capsule 10's.
If you take more than the recommended dose of Apremex 50 Capsule 10's, it may be very harmful to your health. Therefore, you are advised to take Apremex 50 Capsule 10's in the dose and for the duration prescribed by your doctor. However, if you have irregular heartbeats (faster or slower), low blood pressure, nausea, fits, or hallucinations, contact your doctor immediately.
The side effects of Apremex 50 Capsule 10's include dizziness, headache, stomach pain, chest discomfort, insomnia (difficulty sleeping) and tremor. If these side effects persist or worsen, please consult your doctor.
No, Apremex 50 Capsule 10's is not a beta blocker. It is a sodium channel blocker and belongs to the class of medicines called antiarrhythmics. It blocks the fast sodium channels in heart, and thus, helps in treating ventricular arrhythmia (abnormal electrical activity). It blocks specific electrical signals in the heart and stabilizes the heart rhythm.
Apremex 50 Capsule 10's may lower heart rate. Also, it may also cause irregular heartbeats, palpitations, decrease in blood pressure and atrial fibrillation (abnormal heart rhythm). Thus, you will be hospitalized probably when you start using Apremex 50 Capsule 10's. Your doctor will monitor you carefully during this time and for as long as you continue to take Apremex 50 Capsule 10's.
Yes, Apremex 50 Capsule 10's may cause liver damage. This may occur within a few weeks after starting Apremex 50 Capsule 10's and is more likely to happen in patients with heart failure. Patients with impaired liver function are monitored carefully. Also, in patients with liver problems, Apremex 50 Capsule 10's stays for more time in body. Inform your doctor if you notice symptoms such as dark or tea-colored urine, fatigue (overtiredness), loss of appetite for several days or longer, or pain and tenderness on the right side of the abdomen. If your skin or the white part of your eyes turn yellow (jaundice), consult your doctor immediately.
Do not stop taking Apremex 50 Capsule 10's suddenly, even if you feel better, unless your doctor tells you to. Stopping it abruptly may cause your irregular heartbeats to return or worsen. If treatment needs to be stopped, your doctor will usually reduce the dose gradually over 1–2 weeks. The duration of treatment varies depending on your condition, and any decision to stop should be made only after your doctor determines it is safe.
Yes, Apremex 50 Capsule 10's should be taken with food or antacids to avoid stomach upset. Take it at the same time every day. Also, drink enough water while sitting in an upright position.
It is best to limit your caffeine intake because Apremex 50 Capsule 10's slows down how your body processes caffeine. This can lead to increased side effects like jitteriness, a racing heart, or trouble sleeping. Talk to your doctor or pharmacist for guidance on safe limits.
Taking Apremex 50 Capsule 10's with food, milk, or a doctor-approved antacid can help reduce heartburn and stomach upset. If the heartburn persists or becomes severe, talk to your doctor.
Yes, dizziness is a common side effect of Apremex 50 Capsule 10's. To manage this safely, try to stand up slowly from a sitting or lying position, and avoid driving or operating machinery if you feel unsteady. Talk to your doctor if the dizziness is severe.
It is recommended to avoid or strictly limit alcohol while taking this medicine. Alcohol can increase the risk of dizziness and may interact with how your body manages your heart rhythm. Talk to your doctor for personalised advice.
Tobacco smoke speeds up how quickly your body clears Apremex 50 Capsule 10's from your system, which can make the medicine less effective. If you start, stop, or change your smoking habits, talk to your doctor immediately so they can adjust your dose if needed.
This medicine should only be used during pregnancy if the potential benefit justifies the potential risk to the unborn baby. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor.
Your doctor will likely order regular electrocardiograms (ECGs) to monitor your heart's rhythm and blood tests to check your liver function and blood counts. Talk to your doctor to understand your monitoring schedule.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Product Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. MedlinePlus. A607064 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Mexiletine Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Drugs and Lactation Database (LactMed®) [Internet]. 2006. [Accessed on 11 Jul. 2023]Check here
  5. CiplaMed CiplaMed. [Accessed on 11 Jul. 2023]Check here
  6. M L Datta-Chaudhari, T D O'Brien. Prophylactic use of mexiletine in the elderly with acute myocardial infarction. NIH National Library of Medicine. National Center for Biotechnology Information. PubMeg.gov. February 1990. [Accessed on 1st June 2022]Check here
  7. CANA AE FARMAKEFTIKA ERGASTIRIA. Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 1st June 2022]Check here

Country of origin

India

Manufacturer/Marketer address

Office No - S1, Ground Floor, G2, G3 Basement, Sharda Chambers, 15 New Marine Lines, Churchgate, Mumbai - 400020, Maharashtra, India.
Other Info - APR0208
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