Apremac 125/80 mg Combipack Capsule | Uses, Side Effects, Price

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Apremac 125/80 mg Combipack Capsule 3's

Apremac 125/80 mg Combipack Capsule 3's, Pack of 1 Tablet

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Composition :

APREPITANT-125MG + APREPITANT-80MG

Manufacturer/Marketer :

Admac Lifesciences(Oncology)

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Apremac 125/80 mg Combipack Capsule

Apremac 125/80 mg Combipack Capsule belongs to a class of drugs called anti-emetics. It is used to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines) in adults and adolescents aged 12 years and above. Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Apremac 125/80 mg Combipack Capsule contains Aprepitant. Aprepitant blocks a chemical that produces vomiting by acting on the neurological system. Thus, it helps prevent nausea and vomiting.

Take Apremac 125/80 mg Combipack Capsule as prescribed. You are recommended to take Apremac 125/80 mg Combipack Capsule for as long as your doctor has advised it. In some cases, Apremac 125/80 mg Combipack Capsule may cause common side effects such as headache, constipation, loss of appetite, tiredness, indigestion, and hiccups. Most of these side effects do not require medical attention and gradually resolve over time. However, inform your doctor if the side effects persist or worsen.

Please tell your doctor if you are allergic to Apremac 125/80 mg Combipack Capsule or any other medicines. Apremac 125/80 mg Combipack Capsule is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Apremac 125/80 mg Combipack Capsule. Avoid driving or operating machinery if you feel dizzy or sleepy after taking Apremac 125/80 mg Combipack Capsule. If you are taking other prescription or non-prescription medicines, inform your doctor before taking Apremac 125/80 mg Combipack Capsule.

Side Effects of Apremac 125/80 mg Combipack Capsule

Headache
Constipation
Loss of appetite
Tiredness
Indigestion
Hiccups

Uses of Apremac 125/80 mg Combipack Capsule

Apremac 125/80 mg Combipack Capsule is used in the treatment of Chemotherapy-induced nausea and vomiting. The detailed uses of Apremac 125/80 mg Combipack Capsule are as follows:<br/>• Chemotherapy-induced nausea and vomiting (CINV) prevention: Apremac 125/80 mg Combipack Capsule helps to prevent nausea and vomiting caused by chemotherapy, which improves patient comfort and quality of life.<br/>• Postoperative nausea and vomiting (PONV) prevention: Apremac 125/80 mg Combipack Capsule can also be used to prevent nausea and vomiting after surgery, which reduces recovery time and complications.<br/>

Directions for Use

• Apremac 125/80 mg Combipack Capsule can be taken with or without food.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Apremac 125/80 mg Combipack Capsule as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Apremac 125/80 mg Combipack Capsule contains Aprepitant, an anti-emetic (a drug used to treat nausea and vomiting) that works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps to prevent nausea and vomiting caused by anti-cancer medicines in adults and adolescents from the age of 12 years.

How Apremac 125/80 mg Combipack Capsule Works

Apremac 125/80 mg Combipack Capsule contains Aprepitant, which blocks a chemical that produces vomiting by acting on the neurological system. Thus, it helps prevent nausea and vomiting.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ÂºC to 25ÂºC or below 30ÂºC.

What if I have taken an overdose of Apremac 125/80 mg Combipack Capsule

Since Apremac 125/80 mg Combipack Capsule is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

Please tell your doctor if you are allergic to Apremac 125/80 mg Combipack Capsule or any other medicines. Apremac 125/80 mg Combipack Capsule is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Apremac 125/80 mg Combipack Capsule. Avoid driving or operating machinery if you feel dizzy or sleepy after taking Apremac 125/80 mg Combipack Capsule. If you are taking any other prescription or non-prescription medicines, inform your doctor before taking Apremac 125/80 mg Combipack Capsule.

Diet & Lifestyle Advise

Eat a healthy and low-fat diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, and plant-based oils, especially in small portions, as it will be easy for digestion.
Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
Increase the intake of fluids. Drink a small amount of water after small intervals to stay hydrated.
Avoid taking greasy or oily foods, as these foods trigger nausea and vomiting.
If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

Therapeutic Class

ANTIEMETICS

Alcohol

Caution

The interaction of alcohol with Apremac 125/80 mg Combipack Capsule is unknown. If you have any concerns regarding this, please discuss them with your doctor.

Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before taking Apremac 125/80 mg Combipack Capsule. Your doctor may prescribe this medicine only if clearly needed.

Breast Feeding

Consult your doctor

It is unknown whether Aprepitant is excreted in breast milk. Hence, if you are a nursing mother, inform your doctor before taking Apremac 125/80 mg Combipack Capsule.

Driving

Caution

Apremac 125/80 mg Combipack Capsule may cause dizziness or drowsiness in some people. Hence, do not drive or operate machinery if you feel dizzy or drowsy after taking Apremac 125/80 mg Combipack Capsule.

Liver

Consult your doctor

If you have liver disease, inform your doctor before taking Apremac 125/80 mg Combipack Capsule. Your doctor may monitor your liver condition.

Kidney

Consult your doctor

If you have kidney problems, inform your doctor before taking Apremac 125/80 mg Combipack Capsule.

Children

Unsafe

Apremac 125/80 mg Combipack Capsule is not recommended for children below 12 years of age.

Have a query?

FAQs

What is the use of Apremac 125/80 mg Combipack Capsule?

Apremac 125/80 mg Combipack Capsule is used to treat Chemotherapy-induced nausea and vomiting.

How does Apremac 125/80 mg Combipack Capsule work?

Can I take erythromycin with Apremac 125/80 mg Combipack Capsule?

You are not recommended to take erythromycin with Apremac 125/80 mg Combipack Capsule as it may increase the blood levels and effects of Apremac 125/80 mg Combipack Capsule. Contact your doctor if your condition changes or you experience side effects such as diarrhoea, constipation, nausea, or loss of appetite. However, please consult your doctor before taking other medicines with Apremac 125/80 mg Combipack Capsule.

Can I take birth control medicines with Apremac 125/80 mg Combipack Capsule?

You are advised not to take hormonal birth control medicines such as birth control pills, implants, skin patches, and certain Intrauterine devices (IUDs) as they may not work properly when taken together with Apremac 125/80 mg Combipack Capsule. Therefore, you are recommended to use another or additional non-hormonal form of birth control method during treatment with Apremac 125/80 mg Combipack Capsule and for up to 2 months after using Apremac 125/80 mg Combipack Capsule.

Country of origin

India

Manufacturer/Marketer address

SCO 84, Sector 5, Panchkula (Haryana) 134112 INDIA.

Other Info - APR0165

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Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:10 AM IST

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FAQs

What is the use of Apremac 125/80 mg Combipack Capsule?

How does Apremac 125/80 mg Combipack Capsule work?

Can I take erythromycin with Apremac 125/80 mg Combipack Capsule?

Can I take birth control medicines with Apremac 125/80 mg Combipack Capsule?

Disclaimer

Author Details

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