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  3. Appilic-60 Tablet 10's

Appilic-60 Tablet 10's, Pack of 10 TabletS
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Appilic-60 Tablet 10's is used in the treatment of epilepsy and the symptoms associated with it, like seizures. It contains Phenobarbital, which works by controlling the abnormal electrical activity in the brain, thereby preventing and controlling seizures. Additionally, it calms down the excited chemicals of the brain and makes a person relaxed, so that the brain can function properly. In some cases, it may cause side effects such as drowsiness, lethargy, residual sedation, vomiting, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Synonym :

PHENOBARBITAL, FENOBARBITAL

Composition :

PHENOBARBITONE-60MG

Manufacturer/Marketer :

Sbs Biotech

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Appilic-60 Tablet 10's

Appilic-60 Tablet 10's belongs to the class of medicines known as 'anti-convulsant drugs', indicated in the treatment of epilepsy and the symptoms associated with it, like seizures. Epilepsy is a neurological disorder in which nerves present in the brain fail to function properly, resulting in seizures, sensations, unusual behaviour, and even sometimes loss of consciousness.

Appilic-60 Tablet 10's consists of Phenobarbital, which works by controlling the abnormal electrical activity in the brain, thereby preventing and controlling seizures. Additionally, it calms down the excited chemicals of the brain and makes a person relaxed so that the brain can function properly.

Take Appilic-60 Tablet 10's as prescribed. Appilic-60 Tablet 10's is usually recommended to take before bedtime so that a person can sleep well and the medicine can work effectively. Your doctor will recommend how often you take Appilic-60 Tablet 10's based on your medical condition. Some patients taking Appilic-60 Tablet 10's may experience unpleasant effects of this medicine that include drowsiness, lethargy, residual sedation, vomiting, and headache. Most of these side effects of Appilic-60 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not increase or decrease the dosing strength of the medicine, as the doctor may initially advise a lower dose of this medicine and then gradually increase the dose to prevent the chances of adverse reactions, including dizziness and drowsiness. This medicine should be used with caution in patients with liver disease, chronic pain, pituitary gland disorder, and pheochromocytoma. Persons who are allergic to Appilic-60 Tablet 10's or any of its constituents, or are taking a blood thinner (such as warfarin) are not allowed to take this medicine.

Uses of Appilic-60 Tablet 10's

Appilic-60 Tablet 10's is used in the treatment of epilepsy/seizures. The detailed uses of Appilic-60 Tablet 10's are as follows:<br/> • Seizure Control: Appilic-60 Tablet 10's is commonly prescribed to manage and treat various types of seizures, particularly in patients with epilepsy.<br/> • Anxiety Relief: Appilic-60 Tablet 10's is used for short-term relief of anxiety, especially when a quick effect is required.<br/> • Sleep Disorders: Appilic-60 Tablet 10's acts as a sedative and may help address insomnia or other sleep-related disorders due to its calming properties.<br/> • Neurological Conditions: Appilic-60 Tablet 10's may be utilized in the symptomatic treatment of certain neurological disorders.<br/> • Alcohol Withdrawal: Appilic-60 Tablet 10's is included in the treatment plans to assist individuals experiencing withdrawal symptoms from alcohol or barbiturates.<br/>

Directions for Use

  • Appilic-60 Tablet 10's can be taken with or without food, as advised by a doctor.
  • Your doctor will determine the dosage and timing of this medication based on your medical condition.
  • Swallow Appilic-60 Tablet 10's as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

Appilic-60 Tablet 10's belongs to a group of medications known as anticonvulsants that are used for the treatment of all types of epilepsy except absence seizures. This medicine works by controlling the abnormal electrical activity of the brain that causes seizures. Additionally, it also calms down the exciting chemicals of the brain so that a person feels relaxed. By controlling seizures, Appilic-60 Tablet 10's allows a person to do daily activities and also reduces the risk of unconsciousness and repeated seizures.

How Appilic-60 Tablet 10's Works

Appilic-60 Tablet 10's contains Phenobarbital, which works by controlling the abnormal electrical activity in the brain, thereby preventing and controlling seizures. Additionally, it calms down the excited chemicals of the brain and makes a person relaxed, so that the brain can function properly.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Appilic-60 Tablet
  • Uncoordinated muscle movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
  • Limit stimulants like tea, coffee and alcohol.
  • Identify triggers and try managing them.
  • Take a break by scheduling time for yourself.
  • Try creative activities like writing, dancing or painting as it helps release tension.
  • Regular eye exams can detect conditions causing Involuntary Eye Movement.
  • Alcohol and drugs should be avoided as they can increase the symptoms of nystagmus.
  • Wearing corrective lenses for refractive errors can reduce eye strain and symptoms.
  • Stress management and getting proper sleep can help to reduce symptoms.

What if I have taken an overdose of Appilic-60 Tablet 10's

Do not take more than the prescribed dose of Appilic-60 Tablet 10's, as it may cause an overdose. The symptoms of an overdose include weak pulse, slow or shallow breathing, little or no urination, pinpoint pupils, cold or clammy skin, feeling cold, or fainting. If you suspect you have taken an overdose or notice any of these symptoms, please consult a doctor immediately.

Drug Warnings

Appilic-60 Tablet 10's is not recommended in patients with severe asthma or COPD, severe liver disease, porphyria, or a history of addiction to phenobarbital. Follow the doctor's advice if you are taking this medication in pregnancy, as seizure control is important during pregnancy. Inform your doctor if you are planning to be pregnant or are pregnant. This is a habit-forming medicine, so never advise it to anyone. Never start or stop taking this drug without asking the doctor. If a person stops taking it without asking the doctor, then they could face withdrawal symptoms like hallucinations, twitching, anxiety, and trouble sleeping. Therefore, the dosage should be reduced gradually before being stopped completely.

Drug-Drug Interactions

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PhenobarbitalIsavuconazole
Critical
PhenobarbitalRitonavir
Critical

Drug-Drug Interactions

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PhenobarbitalIsavuconazole
Critical
How does the drug interact with Appilic-60 Tablet:
When Isavuconazole is taken with Appilic-60 Tablet, may decrease the blood levels of Isavuconazole, which may make Isavuconazole less effective.

How to manage the interaction:
Taking Isavuconazole with Appilic-60 Tablet is not recommended it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
PhenobarbitalRitonavir
Critical
How does the drug interact with Appilic-60 Tablet:
Taking Appilic-60 Tablet with Ritonavir may significantly reduce the blood levels of ritonavir.

How to manage the interaction:
Taking Appilic-60 Tablet with Ritonavir is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. If you notice any unusual symptoms consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
PhenobarbitalLurasidone
Critical
How does the drug interact with Appilic-60 Tablet:
Co-administration of Lurasidone with Phenobarbitalmay result in significantly lower blood levels of lurasidone, making the medication less effective or ineffective in treating the illness.

How to manage the interaction:
There is an interaction between Lurasidone and Appilic-60 Tablet,so it is not recommended. You can take it if a doctor has prescribed it. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
PhenobarbitalVoriconazole
Critical
How does the drug interact with Appilic-60 Tablet:
Using Voriconazole together with Appilic-60 Tablet may significantly reduce the blood levels of voriconazole.

How to manage the interaction:
Taking Voriconazole with Appilic-60 Tablet is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
PhenobarbitalBedaquiline
Critical
How does the drug interact with Appilic-60 Tablet:
Using Bedaquiline together with Appilic-60 Tablet may reduce the blood levels of bedaquiline, which may decrease its effectiveness.

How to manage the interaction:
Taking Appilic-60 Tablet with Bedaquiline is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
PhenobarbitalNimodipine
Critical
How does the drug interact with Appilic-60 Tablet:
When Nimodipine is taken with Appilic-60 Tablet, it may decrease the blood levels of Nimodipine, which may make Nimodipine less effective in treating the condition.

How to manage the interaction:
Taking Nimodipine with Appilic-60 Tablet is not recommended, as it can result in an interaction, but it can be taken if a doctor has advised it. However, consult the doctor if you experience any unusual symptoms while taking the therapy. Do not discontinue any medications without consulting the doctor.
PhenobarbitalChlorpromazine
Critical
How does the drug interact with Appilic-60 Tablet:
When Chlorpromazine is taken with Appilic-60 Tablet, can change the drug levels and effects of both medications.

How to manage the interaction:
Taking Chlorpromazine with Appilic-60 Tablet is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience unusual symptoms, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
PhenobarbitalSodium oxybate
Critical
How does the drug interact with Appilic-60 Tablet:
Using Sodium oxybate together with Appilic-60 Tablet may increase side effects (drowsiness, dizziness, lightheadedness, confusion, depression, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination).

How to manage the interaction:
Taking Sodium oxybate with Appilic-60 Tablet is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
PhenobarbitalPirfenidone
Critical
How does the drug interact with Appilic-60 Tablet:
When Pirfenidone is taken with Appilic-60 Tablet, it can decrease the effects of Pirfenidone.

How to manage the interaction:
Taking Pirfenidone with Appilic-60 Tablet is not recommended but can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
PhenobarbitalRilpivirine
Critical
How does the drug interact with Appilic-60 Tablet:
Using Rilpivirine together with Appilic-60 Tablet may significantly reduce the blood levels of rilpivirine, which may make it less effective.

How to manage the interaction:
Taking Rilpivirine with Appilic-60 Tablet is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • The first thing a person should do is to quit smoking as smoking makes it difficult for Appilic-60 Tablet 10's to work correctly, increases the chances of epileptic attacks, and even damages the lungs. Better to quit it.
  • Include vegetables and fruits in your diet that are rich in antioxidants and support brain health. This will prevent epileptic attacks.
  • Set a sleep and wake-up time and aim for 7-8 hours of sleep.
  • Fatigue is one of the primary reasons that trigger seizures in the body, so sleeping properly can help in relaxing the brain.
  • Do not consume alcohol as it may raise the risk of epileptic attacks.
  • Maintain your happiness and avoid taking emotional stress, as stress can trigger seizures. People who maintain healthy stress levels have reported that they have responded well to the medicine.

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

Appilic-60 Tablet 10's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Being a barbiturate, Appilic-60 Tablet 10's is a habit-forming medicine and can cause dependence. The risk of dependence increases with alcohol use. Do not drink alcohol while taking Appilic-60 Tablet 10's to reduce this risk.

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Pregnancy

Safe if prescribed

Follow all the directions given by your doctor if you are using Appilic-60 Tablet 10's during pregnancy, as controlling seizures is very important at this time. A seizure can harm both the mother and the unborn baby. Tell your doctor if you are pregnant; they will prescribe the correct dose for you.

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Breast Feeding

Safe if prescribed

Appilic-60 Tablet 10's can only be given to breastfeeding mothers if strongly suggested by the doctor.

bannner image

Driving

Caution

Appilic-60 Tablet 10's may cause drowsiness, dizziness, and other symptoms that can affect a person's thinking ability; therefore, avoid engaging in such activities.

bannner image

Liver

Unsafe

Appilic-60 Tablet 10's can not be indicated in patients with severe liver disease. Please discuss with your doctor if you have any concerns.

bannner image

Kidney

Caution

Appilic-60 Tablet 10's can only be advised to patients dealing with kidney disorders if strongly suggested by a doctor.

bannner image

Children

Safe if prescribed

Appilic-60 Tablet 10's is safe for children if prescribed by a doctor. Initially, the child feels sleepy, but soon the child will develop tolerance to the unpleasant effects of the medication.

Have a query?

FAQs

Appilic-60 Tablet 10's is used in the treatment of epilepsy and the symptoms associated with it, like seizures.

Appilic-60 Tablet 10's belongs to a class of medications known as barbiturate anticonvulsants/hypnotics. It works by controlling the abnormal electrical activity in the brain that occurs during a seizure. Additionally, it also calms down the exciting chemicals of the brain so that a person feels relaxed.

Yes, Appilic-60 Tablet 10's is a habit-forming medicine that can cause serious drug addiction so one should talk to their doctor before quitting it completely.

Being barbiturates, Appilic-60 Tablet 10's is a habit-forming medicine that can cause drug addiction in them. The dangers of addiction increase when combined with alcohol, so do not consume alcohol to get better results.

Appilic-60 Tablet 10's can be taken with or without food; however, there are chances of vomiting when taken on an empty stomach. It is better to take Appilic-60 Tablet 10's with one glass of milk or after meals to avoid stomach upset, as suggested by the doctor.

No, do not stop taking Appilic-60 Tablet 10's without confirming with the doctor, as it may worsen or cause a severe seizure. It is better to consult with the doctor, as they may be able to adjust the dosage before completely stopping it.

Appilic-60 Tablet 10's can take approximately 2 to 4 hours for its beneficial action to be noticeable in adults and remains in the body for 10 to 12 hours. It would be better to talk to the doctor for complete information.

If you forget to take a dose of Appilic-60 Tablet 10's, take it as soon as you remember; however, if it is almost time for the next scheduled dose, skip the missed dose and continue with your regular schedule. Continue with the regular dosing schedule. Do not take a double dose to make up for a forgotten dose.

Long-term side effects of Appilic-60 Tablet 10's are changes in the soft tissues of the body. Symptoms include joint pain, discomfort, or thickening in specific areas, such as the palms or soles of the feet. If you experience any of these symptoms, please consult your doctor.

Taking more than the recommended dose of Appilic-60 Tablet 10's can lead to an overdose. Overdose symptoms include drowsiness, speech problems, jerky movements, jerky eye movements, loss of inhibition, reduced reflex response, low body temperature, low blood pressure and breathing problems. If you experience any of these symptoms, please consult your doctor immediately.

Appilic-60 Tablet 10's is used in children to treat and prevent seizures. However, it can cause side effects such as nausea, vomiting, drowsiness, dizziness, and hyperactivity. It's important to monitor your child for any unusual symptoms and consult your doctor if you have any concerns.

No, do not take folic acid while taking Appilic-60 Tablet 10's. Because folic acid interacts with Appilic-60 Tablet 10's and may decrease the levels of Appilic-60 Tablet 10's in your body. Please consult your doctor if you have any concerns.

The duration for taking Appilic-60 Tablet 10's depends on your specific condition and your doctor's recommendations. However, the exact duration should be determined by your doctor based on your response to Appilic-60 Tablet 10's and any side effects you may experience. Therefore, it's essential to follow your doctor's instructions and do not stop taking Appilic-60 Tablet 10's without consulting your doctor.

Yes, there is a test called the phenobarbital test that measures the level of phenobarbital in your blood. If you feel excessively sleepy and experience tremors, balance issues, or double vision, inform your doctor and have your levels checked.

Yes, Appilic-60 Tablet 10's can cause withdrawal symptoms like hallucinations, twitching, anxiety, and trouble in sleeping. So dosage should be reduced gradually before stopping it completely. And also inform your doctor before stopping Appilic-60 Tablet 10's. However, if you experience any of these symptoms, please consult your doctor.

The common side effects of Appilic-60 Tablet 10's are drowsiness, lethargy, residual sedation, vomiting, and headache. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Nanhera Road, Ambala, Haryana.
Other Info - APP0236

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 22, 2025 | 8:40 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.5843.pdf
  2. https://www.drugs.com/mtm/phenobarbital.html
  3. https://www.nhs.uk/conditions/epilepsy/treatment/
  4. https://pdf.hres.ca/dpd_pm/00048221.PDF
  5. https://assets.hpra.ie/products/Human/14840/183148c1-90e4-448f-b8e2-bcd1d99da97b.pdf
  6. https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=894c57ee-0f5f-41a1-9e0d-3f1f8fdfc9ab&amp;type=pdf
  7. https://www.efda.gov.et/wp-content/uploads/2023/08/Phenobarbital_Phenobarbital-Tablets-100_Medicamen-Biotech-Ltd.pdf
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