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compositionComposition:CYPROHEPTADINE-2MG/ML
prescription
Prescription Medicine
info
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Apilysin-G Syrup 100 ml is used to treat allergy symptoms. It contains Cyproheptadine, which works by blocking the action of histamine, a substance responsible for causing allergic reactions. In some cases, this medicine may cause side effects such as drowsiness, dizziness, constipation, blurred vision, restlessness, dry mouth, nose, or throat. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CYPROHEPTADINE-2MG/ML

Manufacturer/Marketer :

Diamond Drugs Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Apilysin-G Syrup 100 ml

Apilysin-G Syrup 100 ml is a syrup used to relieve allergy symptoms such as watery eyes, runny nose, sneezing, and skin itching or hives. It is also prescribed to help stimulate appetite and promote weight gain in individuals who struggle to consume enough nutrients. This medicine works by targeting specific natural chemicals in your body to reduce allergic reactions and support nutritional intake.

For best results, you should take this syrup consistently at the times recommended by your doctor. You can take Apilysin-G Syrup 100 ml with or without food, though taking it with meals can help prevent stomach upset. Combining this treatment with a balanced diet and regular, small meals can further support your nutritional and recovery goals.

While taking Apilysin-G Syrup 100 ml, you may experience mild side effects like drowsiness, dry mouth, or dizziness. These symptoms are usually temporary as your body adjusts, but you should contact your doctor immediately if you experience severe allergic reactions, confusion, or a rapid heart rate.

Talk to your doctor before starting this medicine if you have underlying conditions such as glaucoma, asthma, high blood pressure, or difficulty urinating due to an enlarged prostate. Do not take this if you are treating a newborn or premature infant, or if you have a known blockage in your stomach or urinary tract.

Avoid consuming alcohol while taking this medicine, as it can significantly increase drowsiness and coordination issues. You should also consult your healthcare provider if you are pregnant, breastfeeding, or an older adult, as specific dose adjustments or safety precautions may be necessary for these groups.

Uses of Apilysin-G Syrup 100 ml

Apilysin-G Syrup 100 ml is used to relieve allergy symptoms such as watery eyes, runny nose, sneezing, and skin itching or hives. The detailed uses of Apilysin-G Syrup 100 ml are as follows:

  • Allergic reactions: It helps relieve symptoms of seasonal allergies, such as sneezing, watery eyes, and an itchy nose or throat.
  • Skin itching and hives: It reduces swelling, redness, and severe itching caused by hives, skin allergies, or insect bites.
  • Appetite loss: It helps stimulate a healthy appetite in individuals experiencing unexplained weight loss or poor nutritional intake.
     

Key Benefits

Apilysin-G Syrup 100 ml helps relieve allergy symptoms while also supporting appetite in people with reduced food intake. With regular use as prescribed, it helps improve daily comfort, promotes better nutrition, and supports overall well-being.

  • Relieves Allergy Symptoms: By blocking the effects of histamine, this medicine helps reduce sneezing, runny nose, watery eyes, itching, hives, and other allergy-related symptoms, allowing you to carry out your daily activities more comfortably.
  • Improves Comfort and Sleep: By calming skin irritation and reducing itching, this medicine helps minimise discomfort and promotes more restful sleep, especially when allergy symptoms are troublesome at night.
  • Supports Healthy Appetite: This medicine helps stimulate appetite in people with poor nutritional intake, encouraging better food consumption, improving energy levels, and supporting recovery and overall health.
Side effects of Apilysin-G Syrup 100 ml
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.

Directions for Use

  • Apilysin-G Syrup 100 ml can be taken with or without food.
  • It is usually taken 2 to 3 times a day. However, follow your doctor's instructions on the dosage and timing of this medication.
  • Measure the prescribed dose using the measuring cup provided in the pack and administer it orally.
  • Shake the bottle well before use. Avoid using regular household spoons, as they may not measure the dose correctly.

How Apilysin-G Syrup 100 ml Works

Apilysin-G Syrup 100 ml contains cyproheptadine, which works by blocking histamine, a natural substance your body releases during an allergic reaction. By stopping histamine from binding to its receptors, Apilysin-G Syrup 100 ml quickly reduces classic allergy symptoms like swelling, redness, watery eyes, and itching. At the same time, it acts on another chemical messenger in the brain called serotonin. By blocking serotonin activity in the brain's appetite control centre, the medicine helps stimulate your appetite, making it easier to consume necessary nutrients and maintain a healthy weight.
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Alcohol

Unsafe

Avoid consumption of alcohol with Apilysin-G Syrup 100 ml as it may increase the risk of adverse effects such as drowsiness, dizziness or difficulty in concentrating. Please consult a doctor before consuming alcohol with Apilysin-G Syrup 100 ml.

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Pregnancy

Consult your doctor

Apilysin-G Syrup 100 ml is a category B pregnancy drug and is given to pregnant women only if the doctor thinks it is essential. Please consult a doctor if you are pregnant.

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Breast Feeding

Consult your doctor

Apilysin-G Syrup 100 ml is given to breastfeeding women only if the doctor thinks the benefits outweigh the risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Apilysin-G Syrup 100 ml may cause drowsiness, dizziness or low blood pressure in elderly people. Therefore, drive only if you are alert and have a clear vision after taking Apilysin-G Syrup 100 ml.

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Liver

Consult your doctor

Take Apilysin-G Syrup 100 ml with caution, especially if you have a history of Liver diseases or conditions. Your doctor may adjust the dose as needed.

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Kidney

Consult your doctor

Take Apilysin-G Syrup 100 ml with caution, especially if you have a history of Kidney diseases or conditions. Your doctor may adjust the dose as needed.

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Children

Unsafe

Apilysin-G Syrup 100 ml is not recommended for children below 2 years as the safety and effectiveness were not established.

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Heart

Caution

Apilysin-G Syrup 100 ml should be used with caution if you have heart problems, as it may cause side effects like low blood pressure or a fast heart rate.

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Geriatrics

Caution

Apilysin-G Syrup 100 ml should be used cautiously in geriatric patients, as older adults may be more sensitive to its side effects like drowsiness, dizziness, and confusion. It’s important to consult your doctor before using it to ensure it’s safe and properly dosed for your age and health condition.

What if I have taken an overdose of Apilysin-G Syrup 100 ml

If you suspect an overdose, seek immediate medical attention. Symptoms of an overdose may include extreme sleepiness, coordination issues, dry mouth, large pupils, or, in some cases, severe excitement or seizures.

Diet & Lifestyle Advise

  • Manage dry mouth: Drink small sips of water throughout the day, suck on sugar-free hard candies, or chew sugarless gum to keep your mouth moist.
  • Identify allergy triggers: Keep a diary to track and avoid environmental allergens like pollen, dust mites, pet dander, or strong perfumes that can worsen your symptoms.
  • Focus on nutrition: If you are taking this medicine to stimulate appetite, eat frequent, small meals rich in proteins and healthy fats rather than three large, heavy meals.
  • Prioritise safety: Avoid driving, operating machinery, or performing tasks that require full mental alertness until you know how this syrup affects you.
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Have a query?

How Soon It Starts Working

The time required for Apilysin-G Syrup 100 ml to start to work: The time required for Apilysin-G Syrup 100 ml to show its action is unknown. The time for which the effects of Apilysin-G Syrup 100 ml last: The duration of action for Apilysin-G Syrup 100 ml is unknown.

What if you forget to take Apilysin-G Syrup 100 ml

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

•Store Apilysin-G Syrup 100 ml oral syrup at a controlled room temperature between 20°C and 25°C (68°F and 77°F).

Drug Warnings

  • Before every dose, visually inspect the syrup in the light; it should look consistent and free of any visible floating particles or discolouration.
  • Always use the syringe or measuring cup provided with this specific bottle, as household spoons vary in size and can lead to taking the wrong amount.
  • Do not drink alcohol or use other substances that cause drowsiness while taking this syrup, as the combination can lead to dangerous sedation.
  • Talk to your doctor if you plan to have allergy skin tests, as this medicine can affect the test results; you may need to stop taking it a few days beforehand.
     

Drug-Drug Interactions

verifiedApollotooltip
  • MAO Inhibitors (MAOIs): Taking this medicine with MAOIs can prolong and increase the side effects of Apilysin-G Syrup 100 ml, such as severe dry mouth and drowsiness.
  • Sedatives and Sleep Aids: Combining this syrup with medications that cause sleepiness (such as sleeping pills, anxiety drugs, or muscle relaxants) may cause extreme drowsiness and slowed breathing.
  • Anticholinergic Drugs: Medicines used for bladder control or stomach cramps can increase the risk of dry mouth, blurred vision, and difficulty urinating when taken with Apilysin-G Syrup 100 ml.
CyproheptadineLinezolid
Critical
CyproheptadinePotassium chloride
Critical

Drug-Drug Interactions

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CyproheptadineLinezolid
Critical
How does the drug interact with Apilysin-G Syrup 100 ml:
Using linezolid together with Apilysin-G Syrup 100 ml may increase side effects of Apilysin-G Syrup 100 ml.

How to manage the interaction:
Taking Apilysin-G Syrup 100 ml with Linezolid is not recommended, consult a doctor before taking it. Contact a doctor if you experience dizziness, drowsiness, blurred vision, dry mouth, constipation, heat intolerance, flushing, decreased sweating, difficulty urinating, palpitation, rapid heartbeat, confusion, disorientation, and memory problems. Do not stop using any medications without talking to a doctor.
CyproheptadinePotassium chloride
Critical
How does the drug interact with Apilysin-G Syrup 100 ml:
Taking Apilysin-G Syrup 100 ml with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Apilysin-G Syrup 100 ml with Potassium chloride is not recommended, as it can lead to an interaction, can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not stop any medication without talking to a doctor.
CyproheptadinePotassium citrate
Critical
How does the drug interact with Apilysin-G Syrup 100 ml:
Taking Apilysin-G Syrup 100 ml and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Apilysin-G Syrup 100 ml with Potassium citrate is not recommended, as it may lead to an interaction but can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
CyproheptadineProcarbazine
Critical
How does the drug interact with Apilysin-G Syrup 100 ml:
Using procarbazine together with Apilysin-G Syrup 100 ml may increase side effects.

How to manage the interaction:
Taking Apilysin-G Syrup 100 ml with Procarbazine is not recommended, please consult your doctor before taking it. Call a doctor if you experience dizziness, drowsiness, blurred vision, dry mouth, constipation, heat intolerance, flushing, decreased sweating, difficulty urinating, palpitation, rapid heartbeat, confusion, disorientation, and memory problems.
CyproheptadineSodium oxybate
Severe
How does the drug interact with Apilysin-G Syrup 100 ml:
Taking Apilysin-G Syrup 100 ml with sodium oxybate can enhance the risk of negative effects.

How to manage the interaction:
Although there is a possible interaction between Apilysin-G Syrup 100 ml and Sodium oxybate, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like feeling tired, dizzy, confused or having low blood pressure or difficulty breathing, make sure to contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
CyproheptadineKetamine
Severe
How does the drug interact with Apilysin-G Syrup 100 ml:
Using ketamine together with Apilysin-G Syrup 100 ml may increase side effects.

How to manage the interaction:
Although taking Ketamine and Apilysin-G Syrup 100 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you feel dizzy, sleepy, confused, have trouble focusing, lazy, or have trouble breathing, make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.
CyproheptadineEsketamine
Severe
How does the drug interact with Apilysin-G Syrup 100 ml:
Combining Apilysin-G Syrup 100 ml with Esketamine can increase the side effects.

How to manage the interaction:
Although there is a possible interaction between Apilysin-G Syrup 100 ml and Esketamine, you can take these medicines together if prescribed by your doctor. If you're having trouble with feeling tired, confused or finding it hard to focus, consult a doctor. Do not stop using any medications without talking to a doctor.
CyproheptadineZonisamide
Severe
How does the drug interact with Apilysin-G Syrup 100 ml:
Coadministration of Apilysin-G Syrup 100 ml with Zonisamide can lead to increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Apilysin-G Syrup 100 ml with Zonisamide together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience changes in blood pressure, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Consuming alcohol while taking this medicine can severely increase drowsiness, dizziness, and coordination problems.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIALLERGIC]

FAQs

Apilysin-G Syrup 100 ml is used to treat symptoms of allergies such as itching, runny nose, sneezing, or watery eyes. It also helps stimulate appetite.
Apilysin-G Syrup 100 ml contains Cyproheptadine, an anti-allergic drug that works by blocking the action of histamine, a substance responsible for allergic reactions. It provides relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.
Apilysin-G Syrup 100 ml may cause dry mouth as a temporary side effect in some people. It is not necessary for everyone taking Apilysin-G Syrup 100 ml to experience this side effect. However, to avoid such side effects, drink plenty of water, regularly rinse your mouth, practice good oral hygiene and suck on sugarless candy. However, if the condition persists or worsens, please consult a doctor.
It is not recommended to take Apilysin-G Syrup 100 ml with topiramate (an anticonvulsant) as co-administration of these two medicines may increase the risk of adverse effects such as reduced sweating and increased body temperature. Heatstroke and hospitalization may occur in a few people, especially during hot weather and vigorous exercise. However, please consult a doctor before taking Apilysin-G Syrup 100 ml with other medicines.
You are recommended to take Apilysin-G Syrup 100 ml for as long as your doctor has prescribed it. However, if the symptoms persist or worsen, such as rash, fever, or persistent headache, after one week of using Apilysin-G Syrup 100 ml, please consult your doctor.
Apilysin-G Syrup 100 ml may be used to prevent and treat migraine headaches, especially in children. It reduces the intensity and frequency of headaches. However, please consult a doctor before taking Apilysin-G Syrup 100 ml.
You are recommended to avoid taking Apilysin-G Syrup 100 ml if you have asthma, glaucoma, enlarged prostate, urinary problems, stomach ulcer or blockage. However, if you have any of these conditions, please inform your doctor before taking Apilysin-G Syrup 100 ml.
Yes, drowsiness is a very common side effect of Apilysin-G Syrup 100 ml. You should avoid driving, operating machinery, or performing hazardous tasks until you know how this medicine affects you. Talk to your doctor if you experience extreme sleepiness that does not go away.
Yes, you can take Apilysin-G Syrup 100 ml with or without food. If you experience an upset stomach after taking the syrup, taking it with a meal or a glass of milk can help soothe your stomach. Talk to your doctor or pharmacist if stomach discomfort persists.
The safety of this medicine during pregnancy or breastfeeding is not fully determined. It should only be used if your healthcare provider decides the benefits outweigh the risks. Talk to your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding.
This medicine can stimulate your appetite, which may lead to weight gain if you consume more food. However, you should only use it for this purpose under the close supervision of a healthcare provider. Talk to your doctor to determine the underlying cause of your appetite loss.
Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and resume your normal dosing schedule. Do not take extra medicine to make up for a missed dose, and talk to your doctor if you miss multiple doses.
Apilysin-G Syrup 100 ml can be used in children, but the exact dose must be carefully calculated by a paediatrician based on the child's age and weight. This medicine must never be given to newborns or premature infants. Talk to your doctor before giving this syrup to any child.
It is not recommended to combine Apilysin-G Syrup 100 ml with other antihistamines or cold medicines, as this can severely increase side effects like extreme drowsiness, dry mouth, or blurred vision. Always talk to your doctor or pharmacist before combining any over-the-counter products.
Yes, drowsiness is a very common side effect of Apilysin-G Syrup 100 ml. You should avoid driving, operating machinery, or performing hazardous tasks until you know how this medicine affects you. Talk to your doctor if you experience extreme sleepiness that does not go away.
Yes, you can take Apilysin-G Syrup 100 ml with or without food. If you experience an upset stomach after taking the syrup, taking it with a meal or a glass of milk can help soothe your stomach. Talk to your doctor or pharmacist if stomach discomfort persists.
The safety of this medicine during pregnancy or breastfeeding is not fully determined. It should only be used if your healthcare provider decides the benefits outweigh the risks. Talk to your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding.
This medicine can stimulate your appetite, which may lead to weight gain if you consume more food. However, you should only use it for this purpose under the close supervision of a healthcare provider. Talk to your doctor to determine the underlying cause of your appetite loss.
Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and resume your normal dosing schedule. Do not take extra medicine to make up for a missed dose, and talk to your doctor if you miss multiple doses.
Apilysin-G Syrup 100 ml can be used in children, but the exact dose must be carefully calculated by a paediatrician based on the child's age and weight. This medicine must never be given to newborns or premature infants. Talk to your doctor before giving this syrup to any child.
It is not recommended to combine Apilysin-G Syrup 100 ml with other antihistamines or cold medicines, as this can severely increase side effects like extreme drowsiness, dry mouth, or blurred vision. Always talk to your doctor or pharmacist before combining any over-the-counter products.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 087056S045Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Cyproheptadine Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. MedlinePlus. Cyproheptadine. [Accessed on 11-Sep-2020]Check here
  4. WebMD. Cyproheptadine. [Accessed on 11-Sep-2020]Check here
  5. Lactmed. Cyproheptadine. [Accessed on 11-Sep-2020]Check here
  6. Bertrand, Valérie et al. Safety of Cyproheptadine, an Orexigenic Drug. Analysis of the French National Pharmacovigilance Data-Base and Systematic Review. National Library of Medicine. (PMC). [Accessed on 18th June 2022]Check here
  7. Najib, Khadijehsadat et al. Beneficial effect of cyproheptadine on body mass index in undernourished children: a randomized controlled trial. National Library of Medicine. (PMC). [Accessed on 18th June 2022]Check here

Country of origin

India

Manufacturer/Marketer address

Diamond Drugs Pvt. Ltd. 37,S.G Mullick Lane Kolkata-700012
Other Info - API0163

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