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  3. Apilok-O Tab 10'S

Apilok-O Tab 10'S, Pack of 10
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Apilok-O Tablet is used to treat gastro-oesophageal reflux disease (GERD), indigestion, heartburn, acid reflux, nausea, and vomiting. It contains Ranitidine and ondansetron, which reduces the amount of acid in the stomach and helps relieve acid-related heartburn and indigestion. Also, it blocks serotonin's action, a natural substance that may cause nausea and vomiting. As a result, it prevents the sensation of nausea and vomiting caused due to conditions like surgery, cancer chemotherapy, pregnancy or motion sickness. It may cause side effects such as diarrhoea, headache, constipation, fatigue, drowsiness, dryness in the mouth, muscle pain and skin flushing. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

ONDANSETRON-4MG + RANITIDINE-150MG

Manufacturer/Marketer :

Apellon Biotech

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Apilok-O Tablet

Apilok-O Tablet belongs to a group of medications called ‘gastrointestinal agent’ and ' anti-emetics'. It is primarily used to treat gastro-oesophageal reflux disease (GERD), indigestion, heartburn, acid reflux, nausea, and vomiting. GERD is a condition in which the valve (sphincter) located at the uppermost part of the stomach gets irritated and damaged due to excessive stomach acid production. As a result, stomach acid enters the food pipe, leading to stomach upset and heartburn. Heartburn is the post-effect of acid reflux with a burning-like feeling that rises from the stomach towards the neck. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is the natural response to the body to discharge the stomach contents forcefully.

Apilok-O Tablet is a combination of two medicines: Ranitidine (antacid) and ondansetron (antiemetics). Ranitidine, which is an H2 blocker (antacid) which reduces the amount of acid in the stomach and helps relieve acid-related heartburn and indigestion. On the other hand, 'Ondansetron' works by blocking serotonin's action, a natural substance that may cause nausea and vomiting. As a result, Apilok-O Tablet prevents the sensation of nausea and vomiting caused due to conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.

Take Apilok-O Tablet as prescribed by your doctor. You are advised to take Apilok-O Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. You may experience diarrhoea, headache, constipation, fatigue, drowsiness, dryness in the mouth, muscle pain and skin flushing. Most of these side effects of Apilok-O Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try to avoid caffeine-containing beverages (tea, coffee), spicy/deep fried/processed food, carbonated drinks, and acidic food like citrus fruits. Tell your doctor if you have allergic to Apilok-O Tablet , have stomach or intestinal cancer, liver problem, or will have an endoscopy in the future. Tell your doctor if you are facing liver, kidney, or heart disorders. A pregnant woman should tell their doctor about their pregnancy as this medicine cannot be used in pregnancy as it may cause a birth deformity in children. Apilok-O Tablet could pass in breastfeeding milk so it should not be given to a woman who is breastfeeding her baby. 

Uses of Apilok-O Tablet

Treatment of Gastroesophageal Reflux Disease (GERD), Acid reflux, Heartburn, Nausea, Vomiting.

Directions for Use

• Take Apilok-O Tablet with or without food or as advised by a doctor.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Apilok-O Tablet is a combination of two medicines: Ranitidine (antacid), and ondansetron (antiemetics).  It is primarily used to treat gastro-oesophageal reflux disease (GERD), indigestion, heartburn, acid reflux, nausea, and vomiting. Apilok-O Tablet contains Ranitidine which helps reduce the excess amount of stomach acid. In turn, it prevents the formation of an ulcer in the stomach (peptic ulcer) or gastroesophageal reflux disease (GERD) with or without an ulcer. On the other hand, Apilok-O Tablet is used to prevent nausea and vomiting associated with cancer chemotherapy, radiotherapy, surgery, pregnancy and motion sickness in adults and children above four years of age. When serotonin level increases in the blood, it stimulates the CTZ receptor (chemoreceptor trigger zone) located in the brain responsible for controlling nausea and vomiting. Apilok-O Tablet acts by inhibiting the release of this serotonin, thereby preventing nausea and vomiting.

How Apilok-O Tablet Works

Apilok-O Tablet is a combination of two medicines: Ranitidine (antacid) and ondansetron (antiemetics). Ranitidine, which is an H2 blocker (antacid) which reduces the amount of acid in the stomach and helps relieve acid-related heartburn and indigestion. On the other hand, 'Ondansetron' works by blocking serotonin's action, a natural substance that may cause nausea and vomiting. As a result, Apilok-O Tablet prevents the sensation of nausea and vomiting caused due to conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.

Storage

Keep Apilok-O Tablet out of the sight and reach of children.

What if I have taken an overdose of Apilok-O Tablet

Do not take more than the prescribed dose of Apilok-O Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

You should avoid taking Apilok-O Tablet if you are allergic to Apilok-O Tablet . Before taking Apilok-O Tablet , inform your doctor if you have stomach cancer, diabetes, or liver disease. People with an irregular heartbeat (arrhythmia) and phenylketonuria (too much protein phenylalanine in the blood) should not take Apilok-O Tablet as it may cause severe conditions. A pregnant woman should tell their doctor about their pregnancy as this medicine cannot be used in pregnancy as it may cause a birth deformity in children. Apilok-O Tablet could pass in breastfeeding milk, so it should not be given to a woman who is breastfeeding her baby. Apilok-O Tablet contains lactose so tell your doctor if you have an intolerance to some sugars.

Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Before going to sleep, try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows, instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the level of production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), preventing backflow of the stomach acid back into the food pipe.
  • A person should take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils and low-fat dairy products will help to keep a person in good health and avoid chances of nausea and vomiting.
  • One should avoid taking greasy or oily foods as this food triggers nausea and vomit.
  • Eat cool foods instead of hot and spicy foods.
  • Include clear broths, non-fat yoghurt, fruit juice, sherbet, and sports drinks for fluid make up which has got lost due to vomiting.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS
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Alcohol

Unsafe

One should avoid consuming alcohol while taking Apilok-O Tablet as this medicine can interact with alcohol and may worsen the side effects.

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Pregnancy

Unsafe

Apilok-O Tablet is not allowed to use in pregnancy as Apilok-O Tablet can seriously affect the fetus or unborn baby.

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Breast Feeding

Caution

Apilok-O Tablet contains Ondansetron that can pass into breast milk, so a lactating mother should tell their doctor before taking this medicine.

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Driving

Caution

Apilok-O Tablet may cause dizziness, low blood pressure, headache, drowsiness as a side effect. A person taking Apilok-O Tablet should avoid driving or operating any heavy machinery or tasks requiring mental alertness.

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Liver

Caution

If you have or had a history or evidence of any liver-related diseases, please consult the doctor before taking Apilok-O Tablet .

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Kidney

Caution

If you have or had a history or evidence of any kidney-related diseases, please consult the doctor before taking Apilok-O Tablet .

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Children

Safe if prescribed

For children, Apilok-O Tablet is used safely and effectively. The dose needs to be adjusted and recommended by a child specialist.

Have a query?

FAQs

Apilok-O Tablet is used to treat gastro-oesophageal reflux disease (GERD), indigestion, heartburn, acid reflux, nausea, and vomiting.

No, Apilok-O Tablet prevents excess production of stomach acid, causing acid reflux and heartburn. If blood is coming in your stool or mucous, immediately contact the doctor.

Tell your doctor if you are facing severe constipation as after checking your condition, the doctor will decide that you can take this medicine or not.

Apilok-O Tablet may cause dizziness, low blood pressure, headache, and drowsiness as a side effect. So, one should avoid driving or operating any machine that requires mental alertness.

Apilok-O Tablet may have some serious side effects, but these are rare. These side effects may include hives, skin rash, itching and difficulty breathing. Inform your doctor in case you notice any of these side effects.

Apilok-O Tablet may pass into a mother's milk, so mothers who are taking Apilok-O Tablet should not breastfeed their child. A woman should tell their doctor if they are breastfeeding mother.

No, Apilok-O Tablet does not have any addictive effects.

Country of origin

India

Manufacturer/Marketer address

No. 8/2, Sarvpriya Vihar, Sarvapriya Vihar, New Delhi-110016, Delhi, India
Other Info - API0115

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:44 AM IST

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Reference

  1. https://www.drugs.com/ranitidine.html
  2. https://www.medicines.org.uk/emc/files/pil.6040.pdf
  3. https://www.drugs.com/ondansetron.html
  4. https://www.medicines.org.uk/emc/files/pil.2332.pdf

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