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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

ANTIPLAR PLUS TABLET is used for the prevention of heart attack and stroke. It contains Aspirin and Clopidogrel, which prevent the formation of a clot in the blood vessels. It helps in the free flow of blood, thereby preventing a heart attack, stroke, deep vein thrombosis (blood clot in the vein), and pulmonary embolism (blood clots in the arteries of the lungs). It may cause common side effects such as abdominal pain, indigestion, diarrhoea, easy bruising, and nosebleeds. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About ANTIPLAR PLUS TABLET

ANTIPLAR PLUS TABLET is used to prevent heart attack and stroke. A heart attack occurs when a blood clot blocks the blood flow to the heart. Signs of a heart attack include chest pain, upper body pain, sweating, nausea, fatigue and trouble breathing.

ANTIPLAR PLUS TABLET is composed of aspirin and clopidogrel, which work by decreasing the production of clots, which is harmful to the body. ANTIPLAR PLUS TABLET helps in the free flow of blood, thereby preventing a heart attack and stroke.

The common side effects of ANTIPLAR PLUS TABLET include abdominal pain, indigestion, diarrhoea, easy bruising, and nosebleeds, dizziness and blurry vision. Most of these side effects of ANTIPLAR PLUS TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Take ANTIPLAR PLUS TABLET after food to avoid any stomach upset. Your physician will decide the dosage based on your medical condition. It is advised not to take more than the recommended dose of ANTIPLAR PLUS TABLET. Do not chew, crush, or break the medicine. It is crucial to have your lipid profile checked regularly.

Let your doctor know if you are sensitive to clopidogrel or aspirin, have kidney/liver diseases, have bleeding issues (like peptic ulcer or brain haemorrhage), are pregnant or are planning to become pregnant or are breastfeeding. Try not to stop taking this medicine of your own. Stopping ANTIPLAR PLUS TABLET may worsen your condition and increase the risk of a future heart attack. 

Uses of ANTIPLAR PLUS TABLET

ANTIPLAR PLUS TABLET is used for the prevention of heart attack and stroke. The detailed uses of ANTIPLAR PLUS TABLET are as follows:

  • Prevention of Blood Clots: ANTIPLAR PLUS TABLET helps to prevent blood clots in patients with heart conditions, thereby reducing the risk of cardiovascular events.
  • Prevention of Heart Attack and Chest Pain: ANTIPLAR PLUS TABLET manages heart attack and unstable angina by preventing blood clots and improving blood flow to the heart.
  • Stroke Prevention: ANTIPLAR PLUS TABLET reduces stroke risk in patients with a history of stroke by preventing blood clots in the brain.

Directions for Use

• Take ANTIPLAR PLUS TABLET with food or as advised by your doctor. • It is advised to take ANTIPLAR PLUS TABLET once daily; however, follow your doctor’s recommendation regarding the dosage and duration. • Swallow ANTIPLAR PLUS TABLET as a whole with a glass of water. • Do not crush, break, or chew it.

Medicinal Benefits

  • ANTIPLAR PLUS TABLET is composed of Aspirin and Clopidogrel, which act as blood thinners (anti-platelet)
  • Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke.
  • Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels).
  • ANTIPLAR PLUS TABLET helps in the free flow of blood, thereby preventing heart attack, stroke, deep vein thrombosis (blood clot in the vein), and pulmonary embolism (blood clots in the arteries of the lungs).

How ANTIPLAR PLUS TABLET Works

ANTIPLAR PLUS TABLET is composed of two medicines: Aspirin and Clopidogrel. These are blood thinners (anti-platelet) that prevent the formation of a clot in the blood vessels. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels).

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of ANTIPLAR PLUS TABLET

Do not take more than the prescribed dose of ANTIPLAR PLUS TABLET as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • You should avoid taking ANTIPLAR PLUS TABLET if you are allergic to ANTIPLAR PLUS TABLET.
  • Let your doctor know if you have a medical condition that is causing bleeding, such as hemophilia, a stomach ulcer or bleeding within your head or bowel.
  • Caution is required before giving ANTIPLAR PLUS TABLET to the liver or kidney disease patients.
  • People affected with respiratory problems like asthma, rhinitis or nasal polyps should consult a doctor before intake of ANTIPLAR PLUS TABLET.
  • ANTIPLAR PLUS TABLET is not recommended for the breastfeeding mother, as it passes into the breast milk.
  • Pregnant or breastfeeding women should consult their physician before taking ANTIPLAR PLUS TABLET, as it can have some harmful effects on the baby (foetus), so your doctor will weigh the benefits and any potential risks before prescribing it to you.
  • ANTIPLAR PLUS TABLET may reduce alertness, affect your vision, or cause dizziness and sleepiness. If these symptoms occur, do not drive.
  • This medicine is not recommended for use in children below 16 years of age as the safety and efficacy have not been established.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Antiplar Plus Tablet:
Combining Ketorolac tromethamine with Antiplar Plus Tablet can increase the risk of adverse effects.

How to manage the interaction:
Taking Antiplar Plus Tablet with Ketorolac tromethamine is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Antiplar Plus Tablet:
Co-administration of Ketorolac and Antiplar Plus Tablet may increase the risk of side effects.

How to manage the interaction:
Taking Ketorolac with Antiplar Plus Tablet is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting fresh or dried blood, severe headache and weakness. Do not stop using any medications without talking to a doctor.
How does the drug interact with Antiplar Plus Tablet:
When Selexipag and Antiplar Plus Tablet are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Antiplar Plus Tablet with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
How does the drug interact with Antiplar Plus Tablet:
Taking Antiplar Plus Tablet together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Antiplar Plus Tablet with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Antiplar Plus Tablet:
Coadministration of Dasatinib with Antiplar Plus Tablet may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Antiplar Plus Tablet and Dasatinib, you can take these medicines together if prescribed by a doctor. However, if you notice bruising, swelling, vomiting, headache, dizziness, or weakness inform a doctor immediately. Do not stop using any medications without consulting a doctor.
AspirinEdoxaban
Severe
How does the drug interact with Antiplar Plus Tablet:
When edoxaban is used with Antiplar Plus Tablet, the risk of bleeding may increase.

How to manage the interaction:
Although there is a possible interaction between Antiplar Plus Tablet and edoxaban, you can take these medicines together if prescribed by a doctor. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Antiplar Plus Tablet:
Using dalteparin with Antiplar Plus Tablet, may enhance the risk of bleeding problems.

How to manage the interaction:
Although there is a possible interaction between Antiplar Plus Tablet and dalteparin, you can take these medicines together if prescribed by a doctor. However, if you notice unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these drugs, inform a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Antiplar Plus Tablet:
Using enoxaparin along with Antiplar Plus Tablet, may enhance the risk of bleeding problems.

How to manage the interaction:
Although there is a possible interaction between Antiplar Plus Tablet and enoxaparin, you can take these medicines together if prescribed by a doctor. However, if you notice unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these drugs, inform a doctor immediately. Do not stop using any medications without consulting a doctor.
AspirinMethazolamide
Severe
How does the drug interact with Antiplar Plus Tablet:
Taking Antiplar Plus Tablet with methazolamide may cause side effects.

How to manage the interaction:
Although there is a possible interaction between Antiplar Plus Tablet and methazolamide, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as ringing in your ears, headache, nausea, vomiting, dizziness, confusion, hallucinations, or rapid breathing, fever, seizure (convulsions), please contact a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Antiplar Plus Tablet:
Combined use of Antiplar Plus Tablet with ramucirumab may result in gut ulcers and bleeding.

How to manage the interaction:
There may be a possibility of interaction between Antiplar Plus Tablet and Ramucirumab, but it can be taken if prescribed by a doctor. However, if you notice unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals.
  • Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take ANTIPLAR PLUS TABLET.
  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits and vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart disease.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on how to notice and manage the early symptoms of heart disease. 

Habit Forming

No

Therapeutic Class

PLATELET AGGREGATION INHIBITOR
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Alcohol

Unsafe

Avoid consuming alcohol since it may worsen the side effects like dizziness and increased blood pressure.

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Pregnancy

Consult your doctor

ANTIPLAR PLUS TABLET is not recommended to use during pregnancy since it may affect the foetus. Please consult your doctor if you are planning to become pregnant or already pregnant before starting ANTIPLAR PLUS TABLET.

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Breast Feeding

Consult your doctor

There is limited data on how ANTIPLAR PLUS TABLET affects breastfeeding. Please consult your doctor before starting ANTIPLAR PLUS TABLET.

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Driving

Unsafe

Do not drive or operate machinery if you experience dizziness or drowsiness while using ANTIPLAR PLUS TABLET. ANTIPLAR PLUS TABLET can also sometimes cause blurry vision, hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver disease. Your doctor will weigh the benefits and potential risks before prescribing ANTIPLAR PLUS TABLET.

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney disease. Your doctor will weigh the benefits and potential risks before prescribing ANTIPLAR PLUS TABLET.

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Children

Unsafe

ANTIPLAR PLUS TABLET is not recommended for children under 16 years. The safety and efficacy of ANTIPLAR PLUS TABLET have not been established in children.

Have a query?

FAQs

ANTIPLAR PLUS TABLET is used for the prevention of heart attack and stroke.

ANTIPLAR PLUS TABLET consists Aspirin and Clopidogrel. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels).

Please consult your doctor if ANTIPLAR PLUS TABLET needs to be discontinued before undergoing surgery. The doctor might ask you to stop taking ANTIPLAR PLUS TABLET a few days before surgery since it can cause an increased risk of bleeding during surgery.

ANTIPLAR PLUS TABLET consists of Aspirin and Clopidogrel. These are blood-thinning agents and can increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails or using sharp objects. Also, please consult your doctor beforehand if you undergo any surgery.

ANTIPLAR PLUS TABLET is generally safe to take for a long time. It works best if you take it for many months or even years. If you are at risk of getting a stomach ulcer, your doctor may prescribe a medicine to treat ulcer, while you're taking ANTIPLAR PLUS TABLET.

Inform your doctor if you suffer from any underlying health conditions such as ulcers, bleeding disorders, stomach swelling, gout, kidney disease, breathing difficulty or asthma that was induced by a painkiller. Also, tell your doctor about all the medications and herbal products you are taking or will soon be taking. Specifically, make sure to mention if you use blood thinners such as aspirin, warfarin and other nonsteroidal anti-inflammatory drugs such as naproxen, as your doctor may need to adjust the dose of your medication or monitor for side effects.

Before undergoing any surgeries or during medical emergencies, inform your doctor that you are taking aspirin, as too much aspirin may result in bleeding disorders.

Take ANTIPLAR PLUS TABLET as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, break or chew it.

ANTIPLAR PLUS TABLET should be used as advised by the doctor for best results, and do not discontinue ANTIPLAR PLUS TABLET on your own without consulting your doctor. Following cardiac bypass surgery, recovery takes time and each person recovers at a slightly different pace.

You may have been prescribed ANTIPLAR PLUS TABLET if you underwent coronary artery bypass graft surgery (CABG), had heart attack, or received treatment with stents in your coronary arteries.

Yes, ANTIPLAR PLUS TABLET is a blood thinner. It works by preventing the formation of a clot in the blood vessels. Thus, it helps to prevent heart attack and stroke.

Take ANTIPLAR PLUS TABLET for as long as it is advised by your doctor. The duration depends on various factors such as type of stent inserted, the illness you are being treated for, any episodes of bleeding experienced by you during treatment, etc. Usually, ANTIPLAR PLUS TABLET is prescribed for a minimum of one year. However, for best results, follow your doctor’s instructions. Do not discontinue on your own without consulting doctor as it may increase the risk of clot formation in the stent, heart attack, and can even lead to death.

You are advised to avoid alcohol consumption while taking ANTIPLAR PLUS TABLET as it may increase the risk of stomach bleeding. However, if you have any concerns, please discuss with your doctor.

ANTIPLAR PLUS TABLET may result in severe bleeding that could be life-threatening. Moreover, even if you suffer a slight injury, such as a small cut from shaving, you may bruise easily and the bleeding may take longer to stop than usual. Seek immediate medical attention if you have prolonged or excessive bleeding. If you observe blood in the urine or black, tarry stools, you should notify your doctor. Watch out for any symptoms of a stroke, such as sudden weakness or numbness on one or both sides of the body, slurred speech, mental confusion, difficulty walking, dizziness, and unexplained headache. Since stroke is an unusual adverse effect of ANTIPLAR PLUS TABLET, call your doctor right away if you experience any of these symptoms.

ANTIPLAR PLUS TABLET is contraindicated in patient who has an allergy to it or any of its ingredients. If you have or have ever had serious liver disease, bleeding in the brain (stroke or transient ischemic attack), stomach ulcers, or bleeding disorders such as haemophilia (a disease in which blood does not clot normally), avoid taking ANTIPLAR PLUS TABLET. If you are pregnant, attempting to conceive, or are breastfeeding, do not take ANTIPLAR PLUS TABLET.

If you forget to take a dose of ANTIPLAR PLUS TABLET, take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.

Avoid activities that could increase the risk of bleeding. Take additional care when shaving or brushing your teeth to prevent bleeding. Additionally, you should not use painkillers; nevertheless, if you must take something like ibuprofen for headache, joint pain, back pain, etc., first consult your doctor. This is due to the possibility of a stomach ulcer and bleeding if you take painkillers along with ANTIPLAR PLUS TABLET. Avoid consuming too much alcohol while using ANTIPLAR PLUS TABLET as this may irritate your stomach and lead to a stomach ulcer.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - ANT0009

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