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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Amtas-AT Tablet is used to treat hypertension (high blood pressure). It contains Amlodipine and Atenolol, which relaxes and widens the constricted blood vessels. This ultimately reduces the heart's workload and makes the heart more efficient in pumping blood throughout the body. Also, it blocks stress hormones like adrenaline and epinephrine, thereby slowing down the increased heart rate. Thus, it helps lower raised blood pressure, reduces the chances of heart attack or stroke in the future. It may cause common side effects such as nausea, sleepiness, ankle swelling, headache, palpitations, low blood pressure, cold extremities, flushing (sense of warmth in the ears, face, neck, and trunk), slow heart rate, oedema (swelling), constipation, tiredness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Amtas-AT Tablet

Amtas-AT Tablet is an anti-hypertensive medication that is used to treat hypertension (high blood pressure). Hypertension is a lifelong or chronic condition in which the blood pressure against the artery walls becomes too high.

Amtas-AT Tablet contains Amlodipine and Atenolol. Amtas-AT Tablet reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. It also blocks stress hormones like adrenaline and epinephrine, thereby slowing down the increased heart rate.

The most common side effects of Amtas-AT Tablet are nausea, sleepiness, ankle swelling, headache, palpitations, low blood pressure, cold extremities, flushing (sense of warmth), slow heart rate, swelling, constipation, tiredness. They do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Take Amtas-AT Tablet with or without food as prescribed by your doctor with a full glass of water. Amtas-AT Tablet may be prescribed alone or in combination with other blood pressure-lowering medicines depending upon your blood pressure levels. Do not chew, bite, or break the medicine.

Inform your doctor if you have had an allergic reaction to Amtas-AT Tablet , are pregnant or are planning to get pregnant, are breastfeeding, have liver disease, kidney disease, heart failure, a heart valve problem or a history of a heart attack.

Uses of Amtas-AT Tablet

Amtas-AT Tablet is used in the treatment of Hypertension (high blood pressure). The detailed uses of Amtas-AT Tablet are as follows:

  • Hypertension Management: Amtas-AT Tablet is frequently prescribed to control high blood pressure, promoting better cardiovascular health.
  • Angina Prevention: Amtas-AT Tablet helps prevent angina attacks by relaxing blood vessels and improving blood flow to the heart.
  • Heart Failure Treatment: Amtas-AT Tablet may be recommended to manage heart failure symptoms by reducing the workload on the heart. Improving Blood Circulation: Amtas-AT Tablet enhances overall blood circulation, ensuring better oxygen delivery to the body's organs and tissues.

Directions for Use

• Amtas-AT Tablet can be taken with or without food as advised by your doctor. • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety. • Swallow Amtas-AT Tablet as a whole with a glass of water. • Do not chew, crush or break it.

Medicinal Benefits

Amtas-AT Tablet is used to treat heart-related conditions like angina (chest pain) and high blood pressure (hypertension).

It is a calcium channel blocker that inhibits the entry of calcium (ions) across the heart that relaxes and widens the smooth muscles for better blood flow.

Besides this, Amtas-AT Tablet helps prevent sudden spasm of the coronary artery (blood vessels of the heart) and reduces how hard the heart has to work to pump blood around the body, lowering its oxygen requirements.

Amtas-AT Tablet improves an individual’s tolerance to physical activity and exercise and keeps their blood pressure normal during exercise. As a result, it overall protects your heart and keeps it healthy.

This medicine helps to lower high blood pressure, reducing the chances of heart attack or stroke.

How Amtas-AT Tablet Works

Amtas-AT Tablet contains Amlodipine (a calcium channel blocker) and Atenolol (a beta-blocker). Amlodipine acts by relaxing and widening the constricted blood vessels. This ultimately reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Atenolol works by blocking stress hormones like adrenaline and epinephrine, thereby slowing down the increased heart rate. Thus, it helps lower raised blood pressure, reducing the chances of heart attack or stroke in the future.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Amtas-AT Tablet

Do not take more than the prescribed dose of Amtas-AT Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Amtas-AT Tablet should not be given to the people allergic to Amtas-AT Tablet .
  • Inform your physician if you have low blood pressure (less than 90 mm of Hg), have had heart attack, or have kidney disease or liver disease before taking Amtas-AT Tablet .
  • Besides this, it is contraindicated in patients with aortic stenosis (heart valve problem).
  • Amtas-AT Tablet can pass into breast milk, but its effect on the baby is not known. So, it is better to tell your doctor if you are taking Amtas-AT Tablet and breastfeeding.
  • Amtas-AT Tablet is to be used in pregnant women only if suggested by the physician.
  • Lifestyle changes are beneficial in achieving optimum outcomes with Amtas-AT Tablet and keeping blood pressure under check.
  • A low-salt diet, daily physical activity (even 20-30 minute brisk walking for 5 days a week can help!), losing weight in the case of people who are obese, etc, are the mainstay of treatment of hypertension.
  • This medicine is not recommended for children below 6 years of age.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AmlodipineMitotane
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Amtas-AT Tablet:
Using Amtas-AT Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Amtas-AT Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AmlodipineMitotane
Severe
How does the drug interact with Amtas-AT Tablet:
Using Amtas-AT Tablet and mitotane together may drastically lower Amtas-AT Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Amtas-AT Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amtas-AT Tablet:
Using Amtas-AT Tablet and phenytoin together may drastically lower Amtas-AT Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Amtas-AT Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineFosphenytoin
Severe
How does the drug interact with Amtas-AT Tablet:
When Amtas-AT Tablet is taken with Fosphenytoin, it may decrease the blood levels of Amtas-AT Tablet, which may make Amtas-AT Tablet less effective.

How to manage the interaction:
Although taking Amtas-AT Tablet and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Amtas-AT Tablet:
Using phenobarbital and Amtas-AT Tablet may drastically lower Amtas-AT Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with Amtas-AT Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineRifapentine
Severe
How does the drug interact with Amtas-AT Tablet:
Coadministration of Amtas-AT Tablet and Rifapentine may significantly reduce the blood levels of Amtas-AT Tablet, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Amtas-AT Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Amtas-AT Tablet:
Using Amtas-AT Tablet and rifabutin together may lower Amtas-AT Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Amtas-AT Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amtas-AT Tablet:
Coadministration of Amtas-AT Tablet and carbamazepine together may significantly reduce Amtas-AT Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Amtas-AT Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Amtas-AT Tablet:
Coadministration of Ceritinib together with Amtas-AT Tablet can slow heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Amtas-AT Tablet with Ceritinib, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Amtas-AT Tablet:
Coadministration of Amtas-AT Tablet and Idelalisib may raise Amtas-AT Tablet levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Amtas-AT Tablet with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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AMLODIPINE-5MG+ATENOLOL-50MGFruit juices, Fruits
Mild

Drug-Food Interactions

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AMLODIPINE-5MG+ATENOLOL-50MGFruit juices, Fruits
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
The consumption of grapefruit juice may slightly increase plasma concentrations of amlodipine. Avoid consumption of grapefruit juice while being treated with Amtas-AT Tablet.

Diet & Lifestyle Advise

  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.

  • Keep your weight under control with a BMI of 19.5-24.9.

  • Avoid chronic stress, as it can raise your blood pressure.

  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Be mindful of salt; consume no more than 2,300 mg each day.

  • Limit or avoid alcohol consumption.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES
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Alcohol

Unsafe

You are recommended not to consume alcohol and Amtas-AT Tablet to avoid unpleasant side effects like lowering blood pressure (hypotension).

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Pregnancy

Unsafe

Amtas-AT Tablet contains atenolol, which is a pregnancy category D drug. It is known to harm the baby if taken during pregnancy. So it is better to avoid intake of Amtas-AT Tablet in pregnant women in their second and third trimesters.

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Breast Feeding

Consult your doctor

Amtas-AT Tablet can pass through the breast milk and harm the baby, so it should not be taken while breastfeeding.

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Driving

Caution

Drive with caution. Amtas-AT Tablet usually causes drowsiness and affects driving ability.

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Liver

Caution

Amtas-AT Tablet to be taken with caution, especially if you have had a history of liver disease.

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Kidney

Caution

Amtas-AT Tablet to be taken with caution, especially if you have had a history of kidney disease.

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Children

Caution

Amtas-AT Tablet is not recommended for children below six years of age without a doctor's consent. The dose is to be adjusted and guided by a child specialist only for children above six years.

Have a query?

FAQs

Amtas-AT Tablet belongs to the class of anti-hypertensive medication used to treat hypertension (high blood pressure).

Amtas-AT Tablet is a combination of anti-hypertensive medications. Amlodipine acts by relaxing and widening the constricted blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Atenolol works by slowing down the heart rate of the heart. Thus, it collectively helps lower high blood pressure, reducing the chances of heart attack or stroke.

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it. If you suddenly stop taking Amtas-AT Tablet , it may cause a jump in blood pressure, chest pain, or can even lead to a heart attack.

Yes, Amtas-AT Tablet is known to cause ankle swelling upon long-term use. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.

High blood pressure during pregnancy is called 'Pregnancy-induced hypertension (PIH). It is harmful to both the baby and the mother. In the mother, very high blood pressure can cause seizures (fits), headache, swelling of feet, kidney damage, and a higher risk of bleeding during pregnancy and during delivery. This can also affect the baby by causing abnormal fetal heart rate, risk of stillbirth and a small baby. So, during pregnancy, you should have regular blood pressure monitoring. Visit your Obstetrician if you have any concerns about blood pressure during pregnancy.

It is also known as fluid retention or fluid overload. Due to oedema, the affected area starts swelling up. If it does not subside, please consult your doctor immediately.

Yes, Amtas-AT Tablet can cause dizziness sometimes, so it is advised to avoid driving or operating heavy machinery while taking Amtas-AT Tablet . In case you feel dizzy or lightheaded, it is recommended to rest for some time until you feel better.

Yes, Amtas-AT Tablet is contraindicated in people with known allergies to any of this medicine's components. It should be avoided in people with severe kidney or liver impairment and people with anuria (reduction or absence of urine). It should also be avoided for use in pregnant women who are in the second and third trimesters of their pregnancy.

The effect of this medicine can be observed within 2 to 4 hours.

Usually, treatment with Amtas-AT Tablet is long-term, even for the rest of your life. Talk to your doctor if you want to stop taking Amtas-AT Tablet .

You should take your medications regularly at the same time. In addition, changing your lifestyle may also help to control blood pressure. These changes include eating a healthy diet low in fat and salt, exercising at least half an hour every day, maintaining a healthy weight, reducing alcohol consumption, and quitting smoking habits.

The most common side effects of Amtas-AT Tablet are nausea, sleepiness, ankle swelling, headache, palpitations, low blood pressure, cold extremities, flushing (sense of warmth in the ears, face, neck, and trunk), slow heart rate, oedema (swelling), constipation, tiredness. They do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

Amtas-AT Tablet contains Amlodipine (a calcium channel blocker) and Atenolol (a beta-blocker).

You should take your medications regularly at the same time. In addition, changing your lifestyle may also help to control blood pressure. These changes include eating a healthy diet low in fat and salt, exercising at least half an hour every day, maintaining a healthy weight, reducing alcohol consumption, and quitting smoking habits.

Dizziness may also occur, especially when you get up suddenly from a lying or sitting position. If you feel dizzy, lie down so you do not faint. Then, sit for a few moments before standing to prevent the dizziness from returning. If you faint, call your doctor right away.

Amtas-AT Tablet is generally safe to take for a long time. In fact, it works best when you take it for a long time. Consult your doctor if you experience any side effects that persist.

You can eat and drink normally while taking Amtas-AT Tablet . Eating a healthy, balanced diet can help if you have high blood pressure or another heart condition.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - AMT0001

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