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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Amlosafe MT 50 Tablet belongs to the class of antihypertensive medicines used in the treatment of high blood pressure. This medicine also helps reduce the chances of heart problems such as heart attack and stroke. It is a combination medicine which suppress the contraction of blood vessels and promote smooth blood flow. It also alters the response to nerve impulses in the heart thereby making the heart pump blood easier. Common side effects include headache, nausea, dizziness, stomach upset, and weakness.
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Manufacturer/Marketer :

Aristo Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Amlosafe MT 50 Tablet

Amlosafe MT 50 Tablet is an antihypertensive agent used to treat high blood pressure/hypertension and angina pectoris. High blood pressure is a condition in which the blood exerts increased pressure on the walls of blood vessels. Angina is basically a pain in the heart and chest. 

Amlosafe MT 50 Tablet contains Metoprolol succinate and Amlodipine. Metoprolol succinate works by slowing down the heart rate, thereby making it more efficient at pumping blood throughout the body. Amlodipine relaxes the blood vessels, thereby improving blood flow. Together, Amlosafe MT 50 Tablet helps treat high blood pressure.

Take Amlosafe MT 50 Tablet as prescribed. In some cases, Amlosafe MT 50 Tablet may cause certain common side effects such as tiredness, dizziness, headache, ankle swelling and slow heart rate. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.

It is advisable to inform the doctor if you are allergic to any of its components. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Keep your doctor informed in case you are due to undergo any surgery or dental procedure. Avoid consuming alcohol with Amlosafe MT 50 Tablet as there may be an interaction. Amlosafe MT 50 Tablet  may cause dizziness; therefore, drive only if you are alert.

Uses of Amlosafe MT 50 Tablet

Treatment of Hypertension and Angina pectoris. The detailed uses of Amlosafe MT 50 Tablet are as follows:<br/>• Treatment of Hypertension: Amlosafe MT 50 Tablet lowers blood pressure by relaxing blood vessels and slowing heart rate.<br/>• Management of Angina (Chest Pain): Amlosafe MT 50 Tablet improves blood flow to the heart, reducing pain and discomfort.<br/>• Support in Chronic Heart Failure: Amlosafe MT 50 Tablet reduces the workload on the heart and improves pumping efficiency.<br/> • Control of Abnormal Heart Rhythms: Amlosafe MT 50 Tablet helps regulate heartbeat and prevent arrhythmias.<br/>

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Directions for Use

• Take Amlosafe MT 50 Tablet with or without food or as advised by a doctor.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Amlosafe MT 50 Tablet is a combination antihypertensive medication containing Metoprolol succinate and Amlodipine. It is used primarily to treat hypertension and to relax the blood vessels for seamless flow of blood. Metoprolol succinate is a beta-blocker that eases the symptoms of hypertension by blocking catecholamines that lead to increased pressure and heart rate. Amlodipine is a calcium channel blocker that decreases blood pressure by preventing the influx of calcium ions into cells and by enlarging and relaxing arteries. In addition, Amlosafe MT 50 Tablet also reduces the oxygen demands of the heart, relaxing the heart and blood vessels and requiring the heart to do less work.

How Amlosafe MT 50 Tablet Works

Amlosafe MT 50 Tablet contains Metoprolol succinate and Amlodipine. Metoprolol succinate works by slowing down the heart rate, thereby making it more efficient at pumping blood throughout the body. Amlodipine relaxes the blood vessels, thereby improving blood flow. Together, Amlosafe MT 50 Tablet helps treat high blood pressure.

Storage

Keep Amlosafe MT 50 Tablet out of the sight and reach of children.
Side effects of Amlosafe MT 50 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.

What if I have taken an overdose of Amlosafe MT 50 Tablet

Do not take more than the prescribed dose. Overdose of Amlosafe MT 50 Tablet may cause low blood pressure, slow pulse rate, shortness of breath, low blood sugar, dizziness, feeling sick and blue discolouration of the skin. Seek immediate medical attention if you suspect that you might have taken an overdose of this medicine.

Drug Warnings

Amlosafe MT 50 Tablet should not be used in case of any known allergy to either of the components. Amlosafe MT 50 Tablet should be used with caution in case of high risk or previous history of any arterial or thrombotic disorders, shock, cardiovascular health disorders, diabetes, heart failure, or any disease-causing psoriasis. Please inform your doctor in case of any history of an overactive thyroid, asthma, phaeochromocytoma (high BP due to a tumour in the adrenal glands), myasthenia gravis (neuromuscular disorder), COPD, heart block, liver disease or renal disease. Consult your doctor before using Amlosafe MT 50 Tablet during pregnancy or breastfeeding. Keep your doctor informed in case you are waiting to undergo any surgery or dental procedure. Amlosafe MT 50 Tablet may interact with alcohol, please consult your doctor before use. Amlosafe MT 50 Tablet may cause dizziness, so drive or operate heavy machinery only if you are alert. 

Drug-Drug Interactions

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AmlodipineDantrolene
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Amlosafe MT 50 Tablet:
Using Amlosafe MT 50 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Amlosafe MT 50 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Amlosafe MT 50 Tablet:
Using Amlosafe MT 50 Tablet and primidone together may lower Amlosafe MT 50 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Amlosafe MT 50 Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amlosafe MT 50 Tablet:
Coadministration of Ceritinib together with Amlosafe MT 50 Tablet can slow heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Amlosafe MT 50 Tablet with Ceritinib, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineEnzalutamide
Severe
How does the drug interact with Amlosafe MT 50 Tablet:
Using a combination of Amlosafe MT 50 Tablet and enzalutamide may drastically lower Amlosafe MT 50 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Taking Amlosafe MT 50 Tablet with enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineNitisinone
Severe
How does the drug interact with Amlosafe MT 50 Tablet:
Coadministration of Amlosafe MT 50 Tablet and Nitisinone may increase the blood levels and effects of Nitisinone.

How to manage the interaction:
Taking Nitisinone with Amlosafe MT 50 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Amlosafe MT 50 Tablet:
Taking simvastatin with Amlosafe MT 50 Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Amlosafe MT 50 Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Amlosafe MT 50 Tablet:
Using phenobarbital and Amlosafe MT 50 Tablet may drastically lower Amlosafe MT 50 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with Amlosafe MT 50 Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amlosafe MT 50 Tablet:
Co-administration of Amlosafe MT 50 Tablet can make Sirolimus may increase the risk of angioedema (a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally also the hands and feet).

How to manage the interaction:
There may be a possibility of interaction between Amlosafe MT 50 Tablet and Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any swelling of the face, eyes, lips, tongue, throat, hands and feet or have trouble breathing or swallowing. Do not stop using any medications without a doctor's advice.
How does the drug interact with Amlosafe MT 50 Tablet:
Co-administration of Tizanidine and Amlosafe MT 50 Tablet can increase the risk or severity of developing side effects like low blood pressure.

How to manage the interaction:
Although co-administration of Amlosafe MT 50 Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Amlosafe MT 50 Tablet:
Coadministration of Amlosafe MT 50 Tablet with itraconazole may significantly raise the blood levels and effects of Amlosafe MT 50 Tablet.

How to manage the interaction:
Amlosafe MT 50 Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.

Drug-Food Interactions

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AMLODIPINE-5MG+METOPROLOL SUCCINATE-50MGFruit juices, Fruits
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+METOPROLOL SUCCINATE-50MGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Amlodipine and Metoprolol with grapefruit and grapefruit juice significantly increases the metabolism of Amlodipine. Avoid taking Amlodipine and Metoprolol with grapefruit and grapefruit juice.

Diet & Lifestyle Advise

  • Limit the intake of salt in your diet.
  • Cut back on foods that are high in fat and cholesterol.
  • Eat more fruits, vegetables and whole-grain foods.
  • Avoid taking Amlosafe MT 50 Tablet with grapefruit juice as there may be an interaction.
  • Avoid tobacco use. Inform your doctor in case of marijuana use.
  • Dress warmly, as Amlosafe MT 50 Tablet may cause cold extremities.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES
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Alcohol

Unsafe

You are advised not to take alcohol with Amlosafe MT 50 Tablet as there may be an interaction, reducing the therapeutic effects of Amlosafe MT 50 Tablet . Please consult your doctor if you have any concerns.

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Pregnancy

Caution

Amlosafe MT 50 Tablet may be used in pregnancy only if absolutely warranted. Please consult your doctor if you have any concerns.

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Breast Feeding

Caution

Amlosafe MT 50 Tablet is not recommended for use during breastfeeding. Please consult your doctor if you have any concerns.

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Driving

Caution

Amlosafe MT 50 Tablet may cause dizziness or loss of alertness, which may affect your ability to drive.

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Liver

Caution

Amlosafe MT 50 Tablet is not recommended for use in those with established liver disease. Please consult your doctor in case of any concerns.

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Kidney

Caution

Amlosafe MT 50 Tablet is probably safe on the kidney but should be used with caution in those with renal impairment. Please consult your doctor in case of any concerns.

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Children

Unsafe

Amlosafe MT 50 Tablet is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.

FAQs

Amlosafe MT 50 Tablet is used to treat high blood pressure/hypertension and angina pectoris.Â

Amlosafe MT 50 Tablet works by reducing the workload on the heart and vessels and relaxing the vessels to ensure a fluid flow of blood, easing any hypertension and effects of the same.

Do not stop taking Amlosafe MT 50 Tablet without consulting your doctor as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Amlosafe MT 50 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Amlosafe MT 50 Tablet .

Hyponatremia (a term for low blood sodium levels) often results in lowering blood pressure and falls. One of the not so common side-effects of Amlosafe MT 50 Tablet is dizziness and lowered BP. Hence, it is best to consult your physician before taking Amlosafe MT 50 Tablet if you suffer from this condition.

Light-headedness could be a side-effect of Amlosafe MT 50 Tablet . It occurs due to low blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Amlosafe MT 50 Tablet are advised to regularly monitor their blood pressure levels to avoid unpleasant events.

Amlosafe MT 50 Tablet is not known to affect fertility. However, not enough literature and studies exist to ascertain the effect of Amlosafe MT 50 Tablet on fertility. Please consult your doctor in case of any concerns.

Amlosafe MT 50 Tablet may cause certain common side effects such as tiredness, dizziness, headache, ankle swelling and slow heart rate. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.

Change your lifestyle in a few essential ways to control your blood pressure. Start by moving; on most days of the week, try to get in at least 30 minutes of exercise, such as swimming or brisk walking. Next, have a well-balanced diet that is rich in fruits, vegetables, lean protein, and whole foods while being low in processed foods, salt, and bad fats. Keep an eye on your weight, drink moderately, and learn stress-reduction techniques like deep breathing or meditation. Aim for 7-8 hours of sleep per night and stay hydrated throughout the day. Try to give up smoking and limit your daily caffeine consumption to one cup of coffee. Don't forget to consult your healthcare practitioner before making any significant adjustments.

Yes. It is effective. Even so, the effectiveness of Amlosafe MT 50 Tablet depends on various factors, such as the individual's medical history, dosage, and response to the medication. It's important to consult with a healthcare professional to determine if this medication is appropriate for your specific condition and to monitor its effectiveness.

Amlosafe MT 50 Tablet is not typically considered a habit-forming medication.

Take Amlosafe MT 50 Tablet as directed. Swallow the tablet whole with water, and take it at the same time each day. Don't crush or chew the tablet. Continue taking the medication even if you feel well, as it helps control your condition. If you need to stop, consult your doctor first to avoid any issues. Regularly check your blood pressure and heart rate, and follow up with your doctor to adjust your dosage as needed.

Amlosafe MT 50 Tablet should be stored in a cool,and dry place away from sunlight. Keep Amlosafe MT 50 Tablet out of the sight and reach of children.

It is not advisable to smoke when taking Amlosafe MT 50 Tablet . Smoking may lessen this medication's effectiveness and heart-healthy improvement effects. In addition to improving your general health, quitting smoking will help your medication function better.

Amlosafe MT 50 Tablet may interact with other medications. Before taking it, consult your doctor to ensure safe use, especially if you're already taking other medications. Never combine it with other medications without your doctor's guidance.

Before taking any medication, including Amlosafe MT 50 Tablet , be sure to tell your doctor if you have any allergies or health conditions or are pregnant or breastfeeding. This will help ensure your safety and avoid any potential interactions or harm.

Amlosafe MT 50 Tablet is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.
Other Info - AML0356

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