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compositionComposition:AMILORIDE-5MG
prescription
Prescription Medicine
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AMIUR 5MG TABLET is used to treat hypertension (high blood pressure) and oedema (fluid overload). It contains Amiloride, a potassium-sparing diuretic that works by blocking sodium-potassium exchange in the distal tubule of the nephron (the functional unit of the kidney). Sometimes, AMIUR 5MG TABLET may cause side effects such as nausea, vomiting, diarrhoea, headache, glucose intolerance, weakness, muscle cramps, electrolyte imbalance, and increased uric acid levels in the blood.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMILORIDE-5MG

Manufacturer/Marketer :

East West Pharma India Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About AMIUR 5MG TABLET

AMIUR 5MG TABLET is a prescription medication primarily used to treat high blood pressure and fluid retention (swelling) caused by conditions like heart failure. It is designed to help your body get rid of extra salt and water without losing too much potassium. Doctors often prescribe it alongside other fluid-clearing medicines to maintain a healthy mineral balance.

To get the most benefit, you should take AMIUR 5MG TABLET consistently every day, usually once daily in the morning to prevent waking up during the night to urinate. You can take this medicine with or without food, but keeping your routine the same each day is highly recommended. Combining this treatment with a low-salt diet and regular light exercise can significantly improve your results.

While taking AMIUR 5MG TABLET , some people may experience mild side effects like headache, nausea, or mild stomach upset. However, you must contact your doctor immediately if you experience signs of high potassium levels, such as muscle weakness, an irregular heartbeat, or severe dizziness.

Before starting AMIUR 5MG TABLET , it is crucial to discuss your complete medical history with your doctor, especially if you have kidney problems, liver damage, or diabetes. Do not take this if you already have high potassium levels in your blood, severe kidney failure, or if you are taking other potassium-sparing water pills.

This medicine can interact with potassium supplements and certain blood pressure medicines, which can dangerously raise your potassium levels, while alcohol can increase the risk of dizziness and low blood pressure. If you are pregnant, breastfeeding, or are an older adult, talk to your doctor or pharmacist to ensure this medication is safe for your specific situation.

Uses of AMIUR 5MG TABLET

Your doctor may prescribe AMIUR 5MG TABLET to treat the following conditions to help manage symptoms, prevent complications, and improve overall health:

  • High Blood Pressure (Hypertension): AMIUR 5MG TABLET helps lower blood pressure by removing excess sodium and water from your bloodstream, reducing the workload on your heart and blood vessels.
  • Fluid Retention (Edema): For individuals with congestive heart failure or liver issues, AMIUR 5MG TABLET helps reduce swelling in the ankles, feet, and abdomen by promoting urine production.
  • Low Potassium Prevention (Hypokalemia): It is frequently used alongside other diuretics to prevent your body from losing too much potassium, keeping your essential mineral levels balanced.

Key Benefits

Using AMIUR 5MG TABLET as prescribed helps remove excess fluid, control blood pressure, and maintain healthy potassium levels. Here are the key benefits you can expect:

  • Relieves fluid retention: Helps remove excess fluid from the body, reducing swelling in the legs, ankles, and abdomen, making movement and daily activities more comfortable.
  • Supports easier breathing: Reduces the build-up of fluid in the lungs, helping improve breathing, stamina, and overall comfort.
  • Maintains healthy potassium levels: Helps prevent low potassium levels, reducing the risk of muscle cramps, weakness, and abnormal heart rhythms while supporting normal muscle and heart function.
     
Side effects of Amiur 5mg Tablet
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Weight loss without physical activity needs immediate medical attention.
  • Get a physical examination and blood tests done to identify factors causing weight loss that could be related to metabolism and thyroid function.
  • Avoid smoking and alcohol intake as it can alter your liver condition and increase your weight loss.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of weight loss.
  • Talk to your dietician and consume food which can maintain ideal weight.

Directions for Use

  • AMIUR 5MG TABLET should be taken with meals.
  • It is usually taken once a day, or as prescribed by your doctor.
  • Swallow it as a whole with a glass of water.
  • Do not break, chew or crush AMIUR 5MG TABLET .

How AMIUR 5MG TABLET Works

AMIUR 5MG TABLET contains amiloride, a potassium-sparing diuretic that works in the kidneys to help remove excess sodium and water from the body while preventing the loss of potassium. AMIUR 5MG TABLET blocks sodium channels in the later parts of the kidney tubules, reducing the reabsorption of sodium and water back into the bloodstream. This allows more sodium and water to be excreted in the urine, helping lower blood pressure and reduce fluid retention. At the same time, it helps the body retain potassium, maintaining healthy potassium levels and reducing the risk of low potassium associated with other diuretics.
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Alcohol

Caution

Alcohol consumption may cause dizziness. Hence, avoid consumption of alcohol as it may worsen the side effects of AMIUR 5MG TABLET .

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before taking AMIUR 5MG TABLET . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before taking AMIUR 5MG TABLET . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

AMIUR 5MG TABLET may cause side effects such as dizziness or tiredness. Hence, avoid driving or operating machines until you are alert.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking AMIUR 5MG TABLET . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Unsafe

AMIUR 5MG TABLET is not recommended for use in patients with kidney impairment. Hence, if you have a pre-existing or a history of kidney disease, inform your doctor before taking AMIUR 5MG TABLET .

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Children

Unsafe

AMIUR 5MG TABLET is not recommended for use in children as the efficacy and safety have not been established.

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Heart

Caution

If you have a history of heart disease, please inform the doctor before receiving AMIUR 5MG TABLET .

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Geriatrics

Consult your doctor

Limited information available about the use of AMIUR 5MG TABLET in geriatric patients. Please consult your physician.

What if I have taken an overdose of AMIUR 5MG TABLET

If you take too much of AMIUR 5MG TABLET , seek emergency medical attention immediately. Symptoms of an overdose may include extreme dizziness, dehydration, severe muscle weakness, or a very slow or irregular heartbeat. Prompt treatment is important to help prevent serious complications.

Diet & Lifestyle Advise

  • Avoid potassium-rich foods and supplements: Since AMIUR 5MG TABLET keeps potassium in your body, avoid taking potassium supplements or using salt substitutes that contain potassium, as this can lead to dangerously high potassium levels. Limit your intake of high-potassium foods like bananas, oranges, spinach, and potatoes unless advised otherwise by your doctor.
  • Monitor your sodium intake: Reducing the amount of salt in your diet helps prevent fluid accumulation and supports the blood pressure-lowering effects of this medicine. Focus on fresh, whole foods and avoid processed items with high sodium content.
  • Stay hydrated but monitor fluid intake: Drink a normal, healthy amount of water, but do not excessively increase your fluid intake unless instructed by your physician, especially if you are treating heart failure or swelling.
  • Stand up slowly: To prevent dizziness or fainting caused by a sudden drop in blood pressure, take your time when rising from a sitting or lying position.
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How Soon It Starts Working

The time required for AMIUR 5MG TABLET to start to work: AMIUR 5MG TABLET ideally shows its action within 2 to 10 hours after administration. The time for which the effects of AMIUR 5MG TABLET last: The effect of AMIUR 5MG TABLET lasts for 24 hours.

What if you forget to take AMIUR 5MG TABLET

If you miss a dose of AMIUR 5MG TABLET , take it as soon as you remember. However, if it is almost time for your next dose, or if it is late in the evening, skip the missed dose and return to your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store AMIUR 5MG TABLET tablets at controlled room temperature, ideally between 20°C and 25°C (68°F and 77°F).

Drug Warnings

  • Get regular blood tests: You will need routine blood tests to check your kidney function and monitor the potassium levels in your blood while taking AMIUR 5MG TABLET .
  • Check your blood pressure daily: Keep a log of your blood pressure readings at home and share them with your doctor during your appointments.
  • Inspect your tablets: Before taking your dose, inspect the tablets to ensure they are dry, intact, and have not changed colour or crumbled.
  • Be cautious with hot weather: Diuretics can make you more prone to dehydration; drink fluids as advised and seek shade during extreme heat.
  • Inform all healthcare providers: Let your dentist, surgeons, and other doctors know you are taking AMIUR 5MG TABLET before any medical procedures or tests.
  • Keep all blood test appointments: Your doctor will regularly monitor your potassium level, kidney function (serum creatinine), and other blood tests. You may need blood tests within the first 1–2 weeks after starting treatment or after your dose is changed. 
     

Drug-Drug Interactions

verifiedApollotooltip
  • Potassium supplements and potassium-sparing diuretics: Combining these with AMIUR 5MG TABLET significantly increases the risk of developing dangerously high blood potassium levels.
  • ACE inhibitors and ARBs (e.g., lisinopril, losartan): Taking these blood pressure medications with AMIUR 5MG TABLET can also lead to elevated potassium levels and requires careful monitoring.
  • NSAIDs (e.g., ibuprofen, naproxen): These pain relievers can reduce the effectiveness of AMIUR 5MG TABLET and increase the risk of kidney damage.
  • Lithium: AMIUR 5MG TABLET may decrease the kidneys' ability to clear lithium, leading to toxic levels of lithium in the body.
AmilorideDrospirenone
Critical
AmilorideSpironolactone
Critical

Drug-Drug Interactions

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AmilorideDrospirenone
Critical
How does the drug interact with Amiur 5mg Tablet:
Coadministration of Amiur 5mg Tablet with Drospirenone may increase potassium levels in the blood.

How to manage the interaction:
Taking Amiur 5mg Tablet with Drospirenone may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is advised to reduce intake of potassium-rich foods such as tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and potassium-containing salt substitutes. Do not stop using any medications without talking to a doctor.
AmilorideSpironolactone
Critical
How does the drug interact with Amiur 5mg Tablet:
Coadministration of Amiur 5mg Tablet with Spironolactone may increase potassium levels in the blood.

How to manage the interaction:
Taking Amiur 5mg Tablet with Spironolactone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advice.
AmilorideTacrolimus
Severe
How does the drug interact with Amiur 5mg Tablet:
Taking Amiur 5mg Tablet with tacrolimus may increase potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking tacrolimus and Amiur 5mg Tablet together may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medications without consulting a doctor.
AmiloridePotassium citrate
Severe
How does the drug interact with Amiur 5mg Tablet:
When Amiur 5mg Tablet is taken with Potassium citrate, it may raise potassium levels in the blood. High potassium levels can cause hyperkalemia (a high level of the electrolyte potassium in the blood).

How to manage the interaction:
Although taking Amiur 5mg Tablet and Potassium citrate together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you happen to experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
AmilorideLosartan
Severe
How does the drug interact with Amiur 5mg Tablet:
Coadministration of Amiur 5mg Tablet with losartan may increase potassium levels in the blood. 9High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Taking Amiur 5mg Tablet along with losartan may lead to an interaction, but it can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
AmilorideQuinapril
Severe
How does the drug interact with Amiur 5mg Tablet:
Taking Amiur 5mg Tablet with quinapril may cause a rise in potassium levels in blood.

How to manage the interaction:
Although taking Amiur 5mg Tablet and quinapril together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience symptoms including fatigue, disorientation, numbness or tingling, and irregular heartbeats. Do not discontinue any medications without a doctor's advice.
AmilorideEprosartan
Severe
How does the drug interact with Amiur 5mg Tablet:
When taken with eprosartan, Amiur 5mg Tablet may raise potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking Amiur 5mg Tablet and eprosartan together may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
AmilorideLithium
Severe
How does the drug interact with Amiur 5mg Tablet:
Taking lithium with Amiur 5mg Tablet can enhance the effects of lithium.

How to manage the interaction:
Although taking Amiur 5mg Tablet and lithium together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience nausea, vomiting, loose stools, sleepiness, muscular weakness, a shaking sensation, loss of coordination, blurred vision, or ringing in the ears. Do not discontinue any medications without a doctor's advice.
AmilorideOlmesartan medoxomil
Severe
How does the drug interact with Amiur 5mg Tablet:
Taking Amiur 5mg Tablet with olmesartan medoxomil can elevate potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking Amiur 5mg Tablet with olmesartan medoxomil may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
AmilorideFosinopril
Severe
How does the drug interact with Amiur 5mg Tablet:
Coadministration of Fosinopril with Amiur 5mg Tablet may cause a rise in potassium levels in your blood.

How to manage the interaction:
Although taking Amiur 5mg Tablet and fosinopril together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience symptoms including fatigue, disorientation, numbness or tingling, and irregular heartbeats. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Salt substitutes: Many salt substitutes contain potassium chloride, which can interact dangerously with AMIUR 5MG TABLET by severely raising your blood potassium levels.
  • Alcohol: Consuming alcohol while taking this medicine can worsen side effects like dizziness, lightheadedness, and low blood pressure.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[DIURETICS/WATER PILLS]

FAQs

AMIUR 5MG TABLET is used to treat Hypertension, Congestive Heart failure and Oedema.
AMIUR 5MG TABLET consists of Amiloride, which belongs to the class of potassium-sparing diuretics. It works by blocking sodium-potassium exchange in the distal tubule of the nephron (functional unit of the kidney).
AMIUR 5MG TABLET can cause dizziness as one of its side effects. If you feel dizzy, try getting up slowly from a sitting or lying position. If your dizziness is severe or unmanageable, please seek medical advice.
AMIUR 5MG TABLET is not commonly associated with erectile dysfunction (ED). But, the individual response towards AMIUR 5MG TABLET may vary. If you are experiencing erectile dysfunction (ED), please consult your doctor and discuss your issue.
Please don’t stop taking AMIUR 5MG TABLET . Follow your doctor's advice. Stopping without your doctor’s approval can lead to adverse side effects. The doctor will assess your condition and suggest you suitable course to have the best recovery. If you have any concerns about taking AMIUR 5MG TABLET please discuss with your doctor first.
It is beneficial only if you are having low potassium levels in your body. However, your doctor will monitor your potassium levels, as excessive potassium can be harmful. Ensure they stay within a safe range.
AMIUR 5MG TABLET can have an effect on blood sugar levels, particularly in people with diabetes. AMIUR 5MG TABLET may cause (diabetes) an increase in blood sugar levels. So diabetic people need to monitor their blood sugar levels closely while taking this medication.
After reassessing your health condition with Losartan, your doctor might have decided that a combination of AMIUR 5MG TABLET and Hydrochlorothiazide would be more effective for your treatment and recovery. Moreover, Hydrochlorothiazide (diuretic) works well with AMIUR 5MG TABLET to control blood pressure and manage your potassium levels more effectively. It's always best to discuss your treatment plan with your doctor to understand the specific reasons behind their prescription choices.
It’s essential to be cautious when taking aspirin and AMIUR 5MG TABLET . This combination should only be taken with a doctor's prescription. Regular checks on your blood pressure, kidney function, and potassium levels are necessary. Always follow your doctor's instructions to ensure safety.
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
The common side effects of AMIUR 5MG TABLET which may cause in some individuals include nausea, vomiting, diarrhoea, headache, glucose intolerance, weakness, muscle cramps, electrolyte imbalance, and increased uric acid levels in the blood. However, these symptoms vanish as your body adjusts to the medication. If these symptoms worsen, please consult a doctor for relief.
It is generally recommended to take AMIUR 5MG TABLET in the morning. Taking it at night can cause you to wake up multiple times to urinate, which can disrupt your sleep. If you have questions about your dosing schedule, talk to your doctor or pharmacist.
Yes, it is best to limit foods high in potassium, such as bananas, oranges, and leafy greens. Because AMIUR 5MG TABLET helps your body retain potassium, eating too many of these foods can cause potassium levels to rise too high. Talk to your doctor or a dietitian for specific guidance on your diet.
Muscle weakness can be a symptom of high potassium levels, which is a serious condition. If you notice muscle weakness, numbness, tingling, or an irregular heartbeat, seek medical attention immediately. Talk to your doctor to have your blood levels checked.
You should avoid taking nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen without consulting your doctor first. These pain relievers can reduce the effectiveness of AMIUR 5MG TABLET and increase the risk of kidney damage. Talk to your doctor or pharmacist for safer pain relief options.
It is best to limit or avoid alcohol while taking AMIUR 5MG TABLET . Alcohol can lower your blood pressure further, increasing the risk of dizziness, lightheadedness, and fainting when you stand up. Talk to your doctor or pharmacist about safe drinking limits.
AMIUR 5MG TABLET is generally not recommended during pregnancy or breastfeeding unless your doctor decides the benefits outweigh the risks. There may be safer alternatives available to manage your condition. Talk to your doctor to discuss your options.
If you are taking AMIUR 5MG TABLET for swelling, you should notice a reduction in swelling in your legs, ankles, or abdomen, and you may find it easier to breathe. For high blood pressure, you may not feel any different, but regular blood pressure checks will confirm if the medicine is working. Talk to your doctor to monitor your progress.
AMIUR 5MG TABLET can increase potassium levels and affect kidney function. Your doctor will check your potassium, serum creatinine (kidney function), and sometimes other electrolytes before treatment and periodically afterward. Many people also have a blood test within 1–2 weeks of starting treatment or after a dose adjustment.
Possibly. Your doctor may start you on a lower dose and adjust it based on your blood pressure, swelling, kidney function, potassium levels, and how well you respond to treatment. Never change your dose without medical advice.

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Country of origin

INDIA

Manufacturer/Marketer address

No. 10, 2nd Cross, Maravaneri, Salem - 636007, Tamil Nadu.
Other Info - AMI0351
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