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Amifru Plus Tablet is a combination medicine used in the treatment of Oedema (swelling) and hypertension (high blood pressure). This medicine contains amiloride and torsemide, which works by reducing the excess fluid levels in the body and thus reduces swelling. Common side effects include dehydration, electrolyte disturbances (calcium, magnesium, and sodium), headache, nausea, or dizziness

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Amifru Plus Tablet

Amifru Plus Tablet is a prescription medicine used to treat excess fluid buildup in the body, also known as edema. This swelling is often caused by conditions like heart failure, liver disease, or kidney problems. By helping your body get rid of extra water, Amifru Plus Tablet relieves pressure on your heart and blood vessels.

To get the best results, you should take Amifru Plus Tablet regularly at the same time every day, usually in the morning to avoid waking up at night to urinate. You can take this tablet with or without food, but keeping your routine consistent is key. Adopting a low-salt diet and staying moderately active can also greatly support the effects of Amifru Plus Tablet .

Some people taking Amifru Plus Tablet may experience mild side effects like dizziness, headache, or an upset stomach. If you notice severe muscle cramps, extreme thirst, a very slow or irregular heartbeat, or signs of an allergic reaction, you should seek medical help immediately.

Before taking Amifru Plus Tablet , tell your doctor if you have severe kidney disease, liver problems, diabetes, or gout. Do not take this if you are unable to pass urine, have dangerously high potassium levels in your blood, or are allergic to any of its ingredients.

Amifru Plus Tablet can interact with alcohol, blood pressure drugs, and potassium supplements, which may cause your blood pressure to drop too low or potassium levels to rise dangerously. If you are pregnant, planning to breastfeed, or are an older adult, talk to your doctor or pharmacist to make sure Amifru Plus Tablet is safe for you.

Uses of Amifru Plus Tablet

Amifru Plus Tablet is used in the treatment of oedema (fluid overload) and associated conditions. The detailed uses of Amifru Plus Tablet are as follows:

  • Treatment of Oedema (Fluid Retention): Amifru Plus Tablet helps the body remove excess fluid that accumulates in the tissues due to conditions such as heart failure, liver disease, or kidney disorders.
  • Management of Congestive Heart Failure: By reducing excess fluid in the body, Amifru Plus Tablet helps decrease the workload on the heart and relieves symptoms such as swelling and shortness of breath.
  • Support in Resistant Hypertension: In selected patients, Amifru Plus Tablet may help lower high blood pressure when additional fluid removal is needed alongside other antihypertensive treatments.

Key Benefits

Amifru Plus Tablet helps remove excess fluid from the body, reducing swelling and improving overall comfort. By helping maintain a healthy fluid balance, it supports better breathing and makes daily activities easier to perform.

Benefits may include:

  • Helps reduce swelling in the legs, ankles, feet, and abdomen caused by fluid retention.
  • Supports easier breathing by reducing excess fluid that can contribute to shortness of breath.
  • Helps improve comfort and mobility during daily activities.
  • Assists in maintaining a healthy fluid balance in the body.
  • Helps reduce the risk of muscle cramps and weakness by supporting potassium balance.
  • Supports the management of conditions associated with fluid overload when used as prescribed.
Side effects of Amifru Plus Tablet
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

Directions for Use

  • Amifru Plus Tablet can be taken with or without food, as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication. Avoid taking this medication within 4 hours of going to bed to avoid nighttime urination.
  • Swallow Amifru Plus Tablet as a whole with a glass of water.
  • Do not break, chew, or crush it.

How Amifru Plus Tablet Works

Amifru Plus Tablet contains Amiloride and Torsemide. Amiloride: It helps the body remove excess salt and water while helping to retain potassium. This helps prevent low potassium levels during treatment and supports a healthy fluid balance. Torsemide: It is a diuretic (water pill) that helps the body remove excess fluid and salt through urine. This helps reduce swelling caused by fluid buildup and helps lower blood pressure.
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Alcohol

Caution

You are recommended not to consume alcohol along with Amifru Plus Tablet to avoid unpleasant side effects.

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Pregnancy

Unsafe

Amifru Plus Tablet must not be taken during pregnancy. Please consult your doctor if you have any concerns.

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Breast Feeding

Unsafe

Breast-feeding must be avoided during treatment with Amifru Plus Tablet . Please consult your doctor if you have any concerns.

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Driving

Caution

It is not recommended to drive after taking Amifru Plus Tablet as it may occasionally cause drowsiness due to orthostatic hypotension (sudden drop in blood pressure on standing from lying position).

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Liver

Caution

Amifru Plus Tablet should be used with caution, particularly if you have a history of liver diseases/conditions. Depending on your current kidney condition, your doctor may adjust your dose.

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Kidney

Caution

Amifru Plus Tablet should be used with caution, particularly if you have a history of kidney diseases/conditions. Depending on your current kidney condition, your doctor may adjust your dose.

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Children

Unsafe

Amifru Plus Tablet is not recommended for children below 12 years of age.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Amifru Plus Tablet . Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Amifru Plus Tablet should be given to elderly patients only if prescribed by a doctor. Please consult your doctor before using Amifru Plus Tablet .

What if I have taken an overdose of Amifru Plus Tablet

If you suspect an overdose or experience severe dizziness, fainting, or weakness after taking too much Amifru Plus Tablet , seek immediate medical attention or contact your local emergency services right away.

Diet & Lifestyle Advise

  • Monitor your salt intake: High amounts of sodium can cause your body to hold onto more water, working against Amifru Plus Tablet . Try to limit processed foods, canned soups, and table salt.
  • Be careful with potassium-rich foods: Because Amifru Plus Tablet helps your body retain potassium, eating too many potassium-rich foods (like bananas, oranges, spinach, or salt substitutes containing potassium) could raise your potassium levels too high. Talk to your doctor or pharmacist about a safe balance.
  • Track your daily weight: Weigh yourself every morning at the same time (after using the bathroom and before breakfast). A sudden weight gain of 2 to 3 pounds in a single day, or 5 pounds in a week, can be a sign of fluid buildup and should be reported to your doctor.
  • Stay hydrated safely: Diuretics help remove water, but you should not restrict or increase your fluid intake dramatically without your doctor's specific guidance.
  • Limit alcohol consumption: Alcohol can lower your blood pressure further, increasing dizziness and the risk of fainting while taking Amifru Plus Tablet .
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How Soon It Starts Working

The time required for Amifru Plus Tablet to start to work: Amifru Plus Tablet ideally shows its action within 1 to 2 hours after administration. The time for which the effects of Amifru Plus Tablet last: The effect of Amifru Plus Tablet lasts for 12 to 24 hours.

What if you forget to take Amifru Plus Tablet

If you miss a dose of Amifru Plus Tablet , take it as soon as you remember. However, if it is already late in the day or close to your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one, as this can increase your risk of side effects.

Storage

• Store Amifru Plus Tablet tablets at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Rise slowly to prevent dizziness: Stand up gradually from sitting or lying positions to help reduce the risk of dizziness, lightheadedness, or fainting.
  • Monitor your blood pressure regularly: Check your blood pressure at home as advised and keep a record to share with your doctor during follow-up appointments.
  • Attend regular monitoring appointments: Keep all scheduled blood test appointments so your doctor can monitor your kidney function and electrolyte levels, including potassium and sodium.
  • Use caution during activities requiring alertness: Avoid driving, operating heavy machinery, or performing hazardous tasks until you know how Amifru Plus Tablet affects you.
  • Report severe fluid loss promptly: Contact your doctor if you develop severe vomiting or diarrhea, as this may lead to dehydration and electrolyte imbalances.

Drug-Drug Interactions

verifiedApollotooltip
  • Potassium supplements or other potassium-sparing diuretics: Taking these medicines alongside Amifru Plus Tablet may increase potassium levels in the blood and raise the risk of serious heart rhythm problems.
  • ACE inhibitors or angiotensin receptor blockers (ARBs): Combining these with Amifru Plus Tablet may increase the risk of high potassium levels and excessively low blood pressure.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g., ibuprofen, naproxen): These medicines may reduce the effectiveness of Amifru Plus Tablet and increase the risk of kidney damage.
  • Medicine for bipolar disorder (e.g., Lithium): Taking lithium alongside Amifru Plus Tablet may increase lithium levels in the body and raise the risk of lithium toxicity.

Drug-Drug Interactions

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How does the drug interact with Amifru Plus Tablet:
Coadministration of Eplerenone with Torasemide and Amiloride may cause a rise in potassium levels in your blood.

How to manage the interaction:
Taking Torasemide and Amiloride with Eplerenone can result in an interaction, but it can be taken if a doctor has prescribed it. However, consult a doctor if you experience symptoms, including fatigue, disorientation, numbness or tingling, and irregular heartbeats. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Amifru Plus Tablet:
Coadministration of Torasemide and Amiloride with Spironolactone may increase potassium levels in the blood.

How to manage the interaction:
Taking torasemide and amiloride with spironolactone is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, or feelings of heaviness in your legs. Do not stop taking any medication without a doctor's advice.
How does the drug interact with Amifru Plus Tablet:
Co-administration of Torasemide and Amiloride can make Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Taking Torasemide and Amiloride with Desmopressin together can result in an interaction, but it can be taken if a doctor has prescribed it. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, confusion, muscle spasms, decreased urination, and sudden weight gain, contact your doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Amifru Plus Tablet:
Taking lithium with Torasemide and Amiloride can enhance the effects of lithium.

How to manage the interaction:
Although taking Torasemide and Amiloride with lithium can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience nausea, vomiting, loose stools, sleepiness, muscular weakness, a shaking sensation, loss of coordination, blurred vision, or ringing in the ears. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Amifru Plus Tablet:
Co-administration of Ziprasidone with Torasemide and Amiloride may increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Ziprasidone with Torasemide and Amiloride can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amifru Plus Tablet:
Coadministration of Ciclosporin with Torasemide and Amiloride may cause a rise in potassium levels in your blood.

How to manage the interaction:
Taking Torasemide and Amiloride with Ciclosporin can result in an interaction, but it can be taken if a doctor has prescribed it. However, consult a doctor if you experience symptoms, including fatigue, disorientation, numbness or tingling, and irregular heartbeats. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Amifru Plus Tablet:
Taking Torasemide and Amiloride together with streptomycin may increase the risk or severity of kidney problems.

How to manage the interaction:
Taking streptomycin with Torasemide and Amiloride can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as blurred vision, dry mouth, dry skin, frequent urination, nausea, and stomach pain, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amifru Plus Tablet:
Taking ramipril with Torasemide and Amiloride may increase the levels of potassium in your blood.

How to manage the interaction:
Although taking Torasemide and Amiloride along with ramipril can result in an interaction, they can be taken together if prescribed by a doctor. However, consult the doctor if you feel weakness, confusion, numbness or tingling, and uneven heartbeats. Do not stop taking any medication without consulting a doctor.
How does the drug interact with Amifru Plus Tablet:
Coadministration of Torasemide and Amiloride with losartan may increase potassium levels in the blood. High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Taking Torasemide and Amiloride along with losartan may lead to an interaction, but it can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Torasemide + AmiloridePotassium acetate
Severe
How does the drug interact with Amifru Plus Tablet:
Taking Potassium acetate with Torasemide and Amiloride may increase potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, and abnormal heart rhythms).

How to manage the interaction:
There may be a possibility of interaction between Potassium acetate and Amiloride, but it can be taken if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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  • Potassium-rich foods (e.g., bananas, leafy greens, potassium-containing salt substitutes): Consuming large amounts of these foods while taking Amifru Plus Tablet may increase potassium levels in the blood.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[DIURETIC]

FAQs

Amifru Plus Tablet is used to treat oedema (fluid retention) caused by conditions such as heart, liver, or kidney disease. It also helps treat high blood pressure by removing excess fluid while helping maintain potassium levels.
Amifru Plus Tablet works by increasing the amount of urine excreted by the kidneys. It effectively treats oedema (swelling) caused by heart, liver, kidney, or lung disease by reducing excess fluid levels in the body.
Fluid retention or overload is a medical term. Oedema causes swelling in the legs, hands, and other body parts, which raises blood pressure. If it does not go away, please see your doctor right away.
Yes, Amifru Plus Tablet has been linked to dehydration (excessive loss of fluids). Dry mouth, decreased urine output, excessive thirst, and hypotension may occur in the patient (decreased blood pressure). As a result, please increase your fluid intake to avoid dehydration.
Yes, Amifru Plus Tablet can cause hyperkalemia (high potassium levels), especially in patients with kidney problems or if you are taking potassium supplements in addition to Amifru Plus Tablet . Please keep an eye on your electrolyte levels regularly to avoid an increase in blood potassium levels.
Amifru Plus Tablet has the potential to cause orthostatic hypotension. This is low blood pressure, which causes dizziness or lightheadedness when you stand up after sitting or lying down. This could be more common when you first start taking this medication. You can avoid this by slowly rising. Consult your doctor if the symptoms persist.
It is generally best to take Amifru Plus Tablet in the morning or early in the day because it increases urine production. Taking it late in the day or at night may cause you to wake up frequently to urinate and disrupt your sleep. Follow your doctor's instructions about the best time to take your medicine.
Amifru Plus Tablet contains a potassium-sparing component, meaning your body holds onto potassium. Eating large amounts of potassium-rich foods like bananas, oranges, or using potassium-based salt substitutes might raise your potassium levels too high. Talk to your doctor or pharmacist for personalized dietary advice.
It is best to avoid or limit alcohol while taking Amifru Plus Tablet . Alcohol can worsen side effects like dizziness and lightheadedness by lowering your blood pressure too quickly. Talk to your doctor about what is safe for you.
Muscle cramps can be a sign of changes in your body's electrolyte levels, such as potassium or sodium. You should contact your doctor right away to have your blood levels checked. Do not start taking supplements without speaking to a medical professional.
Amifru Plus Tablet is generally not recommended during pregnancy because it may harm the unborn baby. If you are pregnant or planning to become pregnant, inform your doctor immediately. Your doctor will decide on a safer alternative if needed. (Remove breastfeeding unless asked separately.)
While Amifru Plus Tablet is used to manage conditions related to kidney function, misuse or dehydration can strain the kidneys. Your doctor will perform regular blood tests to monitor your kidney health. If you notice a sudden decrease in urination, talk to your doctor right away.
No, you should not stop taking Amifru Plus Tablet suddenly, even if you feel better or the swelling has disappeared. Stopping the medication abruptly can cause the fluid buildup and high blood pressure to return quickly. Always talk to your doctor before making any changes to your treatment.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - AMI0425
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