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compositionComposition:DILOXANIDE-500MG
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Amicline Tablet is used to treat intestinal amoebiasis. It contains Diloxanide which interferes with the enzymes required for the survival of amoeba in the intestine. In some cases, this medicine may cause side effects such as nausea, vomiting, headache, hair loss, abdominal pain, abnormal liver function tests, dizziness, and fever. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DILOXANIDE-500MG

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Amicline Tablet

Amicline Tablet is an oral medication primarily used to treat intestinal amoebiasis, which is a parasitic infection of the gut. It specifically targets and clears amoebic cysts from the intestines, making it highly useful for treating individuals who carry the parasite without showing symptoms, as well as those recovering from active infections. This medicine helps ensure the parasite is completely eradicated from the digestive system.

To achieve the best results, you must take this medicine consistently and finish the entire course exactly as prescribed by your doctor. It is typically taken multiple times a day for a set number of days, and taking it with or after meals is recommended to reduce stomach irritation. Adopting strict personal hygiene habits and drinking only safe, treated water during treatment will also help ensure the infection does not return.

Most people tolerate this medication well, though some may experience mild stomach-related side effects such as bloating, gas, or nausea. While these mild symptoms usually go away on their own, you should consult your doctor immediately if you experience signs of a severe allergic reaction, such as a skin rash, swelling, or difficulty breathing.

Before you begin taking this medicine, talk to your doctor if you have a history of liver disease or other chronic health conditions. Do not take this medication if you have a known allergy to any of its ingredients.

It is important to discuss all other medications you are currently taking with your doctor, as some substances may increase digestive discomfort. Additionally, pregnant women, breastfeeding mothers, and elderly individuals should consult their healthcare provider before using this medicine to ensure it is safe for their specific circumstances.

Uses of Amicline Tablet

Amicline Tablet is used to treat intestinal amoebiasis. The detailed uses of Amicline Tablet are as follows:

  • Intestinal amoebiasis: Amicline Tablet is prescribed to treat active parasitic infections of the bowel caused by the parasite Entamoeba histolytica.
  • Asymptomatic cyst passing: It helps eliminate dormant amoebic cysts from the intestines of carriers who do not show active symptoms, preventing them from spreading the parasite to others.
  • Sequential therapy: It is used as a follow-up treatment after a tissue-clearing medicine has successfully treated invasive amoebiasis in other parts of the body.

Key Benefits

Amicline Tablet helps treat intestinal parasitic infections by eliminating harmful parasites from the digestive tract. By clearing both active parasites and, where applicable, their cyst forms, it helps relieve symptoms, supports digestive recovery, and reduces the risk of further transmission.

  • Helps Eliminate Intestinal Parasites: By acting directly within the intestines, Amicline Tablet helps destroy disease-causing parasites, allowing the infection to clear and preventing persistent or recurrent illness.
  • Relieves Digestive Symptoms: As the infection resolves, Amicline Tablet helps reduce abdominal pain, bloating, diarrhoea, and irregular bowel habits, supporting the return of normal digestive function.
  • Helps Prevent the Spread of Infection: By clearing the parasite from infected individuals, including asymptomatic carriers when appropriate, Amicline Tablet helps reduce the risk of transmission to family members and the wider community.

Directions for Use

  • Take Amicline Tablet with or without food, or as advised by your doctor.
  • Follow your doctor's recommendations on the dosage and timing of this medication to achieve optimal results.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Amicline Tablet Works

Amicline Tablet contains diloxanide, which acts directly inside the bowel as a luminal amoebicide. After you swallow the tablet, it reaches the intestines, where it is broken down into its active form. It does not need to be heavily absorbed into your bloodstream to work, which helps keep its effects concentrated right where the parasites live. Once active in the gut, the medicine directly targets and kills the amoebic trophozoites, the active, multiplying stage of the parasite. It also stops them from forming protective cysts, which are the hardy forms of the parasite that spread the infection. By disrupting this lifecycle, the medicine helps your body completely clear the infection from the digestive tract.
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Alcohol

Caution

Alcohol consumption may worsen the side effects of Amicline Tablet like dizziness. It is better to avoid alcohol while you are being treated with Amicline Tablet .

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Pregnancy

Caution

Amicline Tablet is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

It is not safe to breastfeed while taking Amicline Tablet . It is advised to take this drug only if the doctor thinks the benefits outweigh the risks.

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Driving

Caution

Do not drive or operate machinery if you experience any dizziness while using Amicline Tablet .

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Liver

Caution

Amicline Tablet should be used with caution in patients with liver disease. Dose adjustments may be necessary.

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Kidney

Caution

Amicline Tablet should be used with caution in patients with kidney disease. Dose adjustments may be necessary.

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Children

Caution

Amicline Tablet is not recommended for children less than two years of age.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Amicline Tablet . Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Caution

Amicline Tablet should be taken with caution in geriatric patients. Please consult your doctor before using Amicline Tablet .

What if I have taken an overdose of Amicline Tablet

If you accidentally take more than your prescribed dose, seek immediate medical attention. Symptoms of an overdose may include severe stomach pain, persistent nausea, or vomiting.

Diet & Lifestyle Advise

  • Practice strict hygiene: Wash your hands thoroughly with soap and clean water after using the restroom and before preparing or eating food to prevent reinfection.
  • Drink safe water: Stick to bottled, boiled, or properly filtered water to avoid consuming water that may be contaminated with parasite cysts.
  • Avoid raw or unpeeled foods: Eat foods that are thoroughly cooked and served hot. Avoid raw vegetables, salads, and fruits that you have not washed and peeled yourself.
  • Stay hydrated: If you experience loose stools or stomach upset, drink plenty of fluids, such as clean water or oral rehydration solutions, to maintain a healthy fluid balance.
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How Soon It Starts Working

The time required for Amicline Tablet to start to work: Amicline Tablet ideally shows its action within 2 hours after administration. The time for which the effects of Amicline Tablet last: The effect of Amicline Tablet lasts for 6 hours.

What if you forget to take Amicline Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and return to your normal routine. Do not take two doses at the same time to make up for a missed one.

Storage

• Store Amicline Tablet tablets at room temperature, ideally between 15°C and 30°C (59°F to 86°F). • Keep the tablets in their original packaging to protect them from direct sunlight, high heat, and moisture.

Drug Warnings

  • Always finish the entire course of this medicine, even if your digestive symptoms clear up after a few days.
    Do not share this medicine with others, even if they have stomach symptoms similar to yours.
  • Avoid drinking alcohol while taking this medicine, as it can worsen stomach irritation and increase nausea.
  • Inform your doctor immediately if you suspect you are pregnant or if you plan to breastfeed during your treatment.
  • Make sure any family members or close contacts are tested if your doctor suggests it, as silent carriers can easily spread the infection.

Drug-Drug Interactions

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  • Medicines that may irritate the stomach (e.g., NSAIDs such as ibuprofen or aspirin): Although Amicline Tablet has few clinically significant drug interactions, taking it together with medicines that can irritate the stomach may increase the risk of digestive side effects such as nausea, vomiting, stomach pain, or indigestion. Inform your doctor about all medicines you are taking before starting treatment.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Alcohol: There are no specific food interactions known with Amicline Tablet . However, it is advisable to avoid alcohol during treatment, as it may increase the risk of nausea, vomiting, stomach cramps, and other gastrointestinal side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIPROTOZOALS]

FAQs

Amicline Tablet is an antiprotozoal medicine used to treat intestinal amoebiasis (amoebic dysentery), an infection caused by the parasite Entamoeba histolytica. It helps eliminate parasite cysts from the intestines. It is not effective against viral or bacterial infections. Talk to your doctor for the correct diagnosis and treatment.
Amicline Tablet may be taken with or without food, but taking it during or immediately after a meal is recommended because it helps reduce stomach upset, nausea, and abdominal discomfort. If you experience persistent stomach irritation, talk to your doctor.
No, you should never stop taking your medication early. Even if your symptoms have gone, some parasites may still survive in your gut. Completing the full course ensures the infection is completely cleared. Talk to your doctor if you have concerns.
Increased gas is the most common side effect of Amicline Tablet and is usually mild. Eating simple, non-greasy foods and avoiding carbonated drinks can help manage this. Talk to your doctor if the bloating or gas becomes severe.
This medicine is generally avoided during pregnancy, especially in the first trimester, unless your doctor decides it is absolutely necessary. If you are pregnant or planning a pregnancy, talk to your doctor before taking this medicine.
It is highly recommended to avoid alcohol during your treatment. Alcohol can irritate your digestive tract and make common side effects like nausea and stomach cramps worse. Talk to your doctor for more safety advice.
No, Amicline Tablet only works against specific parasitic infections like amoebiasis. It is not effective against viral infections, bacterial food poisoning, or the common flu. Talk to your doctor to get the correct treatment for your symptoms.
To prevent reinfection, always wash your hands before eating, consume hot, well-cooked meals, and drink safe, purified water. Avoid raw street foods or unpeeled fruits. Talk to your doctor or pharmacist for more hygiene tips.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

20, Dr. E. Moses Road, Mahalaxmi, Mumbai - 400 011
Other Info - AMI0005
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