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Albucel LS 20% Solution is a plasma volume expander which helps restore and maintain circulating blood volume in cases where it is low. This medicine works by replenishing blood and other bodily fluids that were lost due to significant bleeding, surgery, or kidney dialysis. Common side effects include tenderness/pain at the injection site, flushing (temporary reddening of the skin), and fever.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Albucel LS 20% Solution

Albucel LS 20% Solution is a prescription fluid used to restore and maintain circulating blood volume in patients who have suffered severe blood or fluid loss. It is commonly used to treat shock caused by major injuries, surgeries, or severe burns, as well as to correct critically low protein levels in the blood.

This medicine is given as an infusion directly into a vein, meaning it does not need to be taken with food. Your doctor will decide how often you need to receive this medicine based on your specific medical condition and how well your body responds to the treatment. To help support your recovery, your healthcare team may recommend specific dietary adjustments, such as maintaining a carefully managed fluid intake and following a low-sodium diet to prevent unnecessary fluid retention.

While Albucel LS 20% Solution is generally well-tolerated, some people may experience mild side effects like temporary flushing, mild fever, chills, or nausea. However, if you notice serious symptoms such as difficulty breathing, sudden severe swelling, or a rapid, pounding heartbeat, you must alert your medical team immediately.

Before receiving this medicine, talk to your doctor if you have a history of chronic kidney disease, high blood pressure, or a known allergy to blood products.

It is crucial to inform your doctor about all other medications you are taking, as some intravenous solutions can interact with Albucel LS 20% Solution , though serious interactions with everyday foods or alcohol are rare. If you are pregnant, breastfeeding, or are an older adult, consult your doctor or pharmacist to discuss any special precautions needed for your care.

Uses of Albucel LS 20% Solution

Your doctor may prescribe Albucel LS 20% Solution to help manage the following conditions:

  • Shock and severe blood loss: Quickly restores circulating blood volume after trauma, major surgery, or severe injury to keep vital organs working properly.
  • Severe burns: Replaces critical fluids and proteins lost through damaged skin, helping to prevent severe dehydration and shock.
  • Low blood protein levels: Corrects low protein levels in the blood caused by conditions like liver failure, kidney disease, or major surgical procedures.
  • Fluid accumulation (ascites): Helps draw excess fluid from body tissues back into the blood vessels so the body can naturally eliminate it.

Key Benefits

When used as directed as part of your treatment plan, Albucel LS 20% Solution may provide the following benefits:

  • Restores blood volume: Helps replace albumin and restore the amount of fluid circulating in your bloodstream when your blood volume or albumin levels are low.
  • Supports blood circulation: Helps maintain adequate blood circulation by keeping fluid inside your blood vessels.
  • Helps manage fluid balance: May draw excess fluid from body tissues back into the bloodstream in conditions where this is appropriate, helping restore the normal balance of fluids in the body.
  • Supports treatment in serious medical conditions: May be used as part of the treatment of certain serious illnesses or after major fluid loss when your doctor determines that albumin replacement is needed.
Side effects of Albucel LS 20% Solution 100 ml
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Rest well; get enough sleep.
  • Wear comfortable layers of clothes and get to a warm place.
  • Drink warm fluids like coffee, tea or hot chocolate.
  • Warm up using a blanket or heating pad.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Include omega-3 rich foods in your diet to reduce inflammation.
  • Eat antioxidant-rich foods like fruits, vegetables, and nuts to promote overall skin health.
  • Stay hydrated by drinking plenty of water.
  • Maintain a healthy skin care routine, using gentle, fragrance-free products.
  • Wear loose, breathable clothing to minimize irritation.
  • Keep fingernails short and clean to prevent further skin damage.
  • Use a humidifier to add moisture to the air, reducing dryness and itchiness.
  • Practice stress-reducing techniques like meditation or deep breathing to manage stress levels.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Albucel LS 20% Solution will be administered by a nurse or doctor.
  • Do not self-administer.

How Albucel LS 20% Solution Works

Albucel LS 20% Solution contains human albumin, a protein that is naturally found in your blood. When given as an intravenous (IV) infusion, it helps keep fluid inside your blood vessels. If you have lost blood or body fluids, or if fluid has leaked into your body tissues, this medicine draws some of that fluid back into your bloodstream. This helps restore the amount of fluid in your blood and supports normal blood circulation. This medicine is made from donated human plasma. The plasma is carefully screened and processed using multiple purification and viral inactivation steps to minimise the risk of transmitting infections.
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Alcohol

Consult your doctor

The interaction of alcohol with Albucel LS 20% Solution is unknown. However, it is advisable not to consume alcohol.

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Pregnancy

Consult your doctor

Please consult the doctor as there are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor as there is no substantial research yet on the use of Albucel LS 20% Solution in breastfeeding/nursing mothers.

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Driving

Caution

Your ability to drive or operate heavy machinery is usually unaffected by Albucel LS 20% Solution .

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Liver

Consult your doctor

If you have a history of liver illness or condition, inform your doctor. Your doctor may alter the dose if necessary.

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Kidney

Consult your doctor

Let your doctor know if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Please consult a doctor. Albucel LS 20% Solution is given to children only if clinically needed.

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Heart

Caution

Albucel LS 20% Solution should be administered with caution in patients with heart problems. Therefore, please talk to your doctor before receiving Albucel LS 20% Solution .

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Geriatrics

Consult your doctor

Limited data is available regarding the use of Albucel LS 20% Solution in elderly patients. Seek medical advice if you have any concerns.

What if I have taken an overdose of Albucel LS 20% Solution

Since this medicine is injected by trained medical staff, they will monitor you closely to prevent an overdose. If you receive too much, you may experience signs of fluid overload, such as sudden shortness of breath, a severe headache, or high blood pressure. If you notice any of these signs during or after your infusion, tell your doctor or nurse right away.

Diet & Lifestyle Advise

  • Follow your doctor's advice: Follow any recommendations about your fluid intake and diet based on your medical condition.
  • Limit salt if advised: If your doctor recommends a low-salt diet, follow it to help manage fluid balance and reduce swelling.
  • Stay hydrated: Drink enough fluids as advised by your healthcare team. Avoid drinking more or less than recommended.
  • Monitor for fluid build-up: Contact your doctor if you notice new or worsening swelling, rapid weight gain, shortness of breath, or reduced urine output.
  • Avoid alcohol if advised: Alcohol may worsen certain medical conditions, especially liver disease, and may interfere with your recovery. Ask your doctor whether you should avoid alcohol during treatment.
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How Soon It Starts Working

  • The time required for Albucel LS 20% Solution to start to work: Albucel LS 20% Solution ideally shows its action within 15 to 30 minutes after administration.
  • The time for which the effects of Albucel LS 20% Solution last: The effect of Albucel LS 20% Solution lasts for 16 to 18 hours.

What if you forget to take Albucel LS 20% Solution

Because Albucel LS 20% Solution is given by healthcare professionals in a controlled medical setting, it is highly unlikely that you will miss a dose. However, if you miss an appointment for your scheduled infusion, contact your doctor's office immediately to reschedule.

Storage

•Store Albucel LS 20% Solution according to the package instructions, typically at room temperature (under 30°C) or in a refrigerator (between 2°C and 8°C), depending on the specific product guidelines. Do not freeze.

Drug Warnings

  • Inspect the vial: The liquid should be clear or slightly yellow. Do not use it if it is cloudy, discoloured, or contains visible particles.
  • Check the packaging: Ensure the vial is intact and has no cracks, leaks, or signs of tampering before use.
  • Routine monitoring: During treatment, your healthcare team will regularly monitor your blood pressure, heart rate, urine output, fluid balance, blood electrolytes, and serum albumin levels to assess your response and help ensure safe treatment.
  • Report symptoms immediately: Tell your doctor or nurse straight away if you feel dizzy, cold, breathless, develop a headache, or notice any unusual symptoms during the infusion.

Drug-Drug Interactions

verifiedApollotooltip
  • ACE inhibitors (such as enalapril or ramipril): Tell your doctor if you take these medicines, as they may increase the risk of a reaction during the infusion.
  • Other intravenous medicines or fluids: This medicine should only be mixed or given with other intravenous medicines or fluids if your healthcare team confirms it is compatible.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Albucel LS 20% Solution when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[BLOOD SUBSTITUTES AND PLASMA EXPANDERS]

FAQs

Albucel LS 20% Solution belongs to the class of medicines called plasma volume expander used to restore and maintain circulating blood volume in cases where it is low.
Albucel LS 20% Solution works by replenishing blood and other bodily fluids that have been lost due to significant bleeding, surgery, or kidney dialysis.
Albucel LS 20% Solution can be used for short term fluid replacement purposes only. In some cases, it may be used for prolonged durations.
Albucel LS 20% Solution may cause flushing (redness, warmth, and tingly feeling). It generally does not require medical attention and gradually resolves over time. However, consult your doctor if it persists or worsens.
Albucel LS 20% Solution may also be used to treat low albumin levels caused by abdominal infections, surgery, liver failure, dialysis, respiratory distress, and ovarian problems.
Let your doctor know if you are allergic to any of the components in Albucel LS 20% Solution , if you are pregnant or breastfeeding, about your health condition and the medicines you are taking.
Vitals such as temperature, pulse, respiration, blood pressure, and heart rate should be monitored before giving Albucel LS 20% Solution .
Albucel LS 20% Solution may cause side effects like tenderness/pain at the injection site, flushing (temporary reddening of the skin), and fever. If the side effects persist or worsen, please consult your doctor.
Albucel LS 20% Solution is given as an infusion directly into a vein by a trained healthcare professional in a clinic or hospital. Talk to your doctor if you have questions about how the infusion is performed.
Yes, because Albucel LS 20% Solution draws fluid back into your blood vessels, it can raise your blood volume and temporarily increase your blood pressure. Your healthcare team will monitor your blood pressure closely during the injection. Talk to your doctor if you experience a pounding headache.
The safety of Albucel LS 20% Solution during pregnancy has not been fully studied, but it may be used if your doctor decides the benefits outweigh the risks. Talk to your doctor if you are pregnant or planning to become pregnant.
It is highly recommended to avoid alcohol, as it can affect your fluid levels and strain your liver and kidneys during treatment. Talk to your doctor or pharmacist for personalised advice.
Long-term side effects are very rare, as most reactions are mild and resolve shortly after the infusion is completed. Talk to your doctor if you experience any lingering health concerns after your treatment.
Chills and mild fever can sometimes happen while receiving this medicine. Inform your nurse or doctor immediately so they can adjust the injection speed or provide comfort measures. Talk to your doctor if you feel unwell after the procedure.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ALB0171
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