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  3. Adiff Gel 15 gm

Adiff Gel 15 gm, Pack of 1 GEL
Adiff Gel 15 gm, Pack of 1 GEL
Adiff Gel 15 gm, Pack of 1 GEL
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Adiff Gel is used to treat acne (pimples) in patients 12 years or older. It contains Adapalene, which works by loosening the cells on the skin's surface and unblocks pores by reducing oil production in the skin. Thereby, decreases pimples, whiteheads, and blackheads. It may cause side effects such as dry skin, irritation, redness, or burning sensation of the skin in some cases. Do not apply this medicine on cuts, open wounds, scrapes, sunburned, windburned, chapped, dry, or irritated skin. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

ADAPALENE-0.1%W/W

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

About Adiff Gel

Adiff Gel is used to treat acne (pimples) in patients 12 years or older. Acne is a common skin condition and occurs when hair follicles are blocked with dead skin cells and oil. The acne-causing bacteria feeds on sebum (natural oil produced by skin), causing redness and swelling.

Adiff Gel contains Adapalene, which works by loosening the cells on the skin’s surface and unblocking pores by reducing oil production. Thus, it decreases pimples, whiteheads, and blackheads.

Use Adiff Gel as prescribed. Adiff Gel is only for external use. Avoid contact of Adiff Gel with nose, ears, mouth, or eyes. In case Adiff Gel comes in contact with these areas accidentally, rinse with warm water thoroughly. Your doctor will advise you how often you take Adiff Gel based on your medical condition. You may experience dry skin, irritation, redness, or a burning sensation of the skin in some cases. Most of these side effects of Adiff Gel do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Adiff Gel or any other medicines, please tell your doctor. Do not apply Adiff Gel on cuts, open wounds, scrapes, sunburned, windburned, chapped, dry, or irritated skin. Avoid exposure to tanning beds or sunlight while using Adiff Gel as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you are pregnant or breastfeeding, please inform your doctor before taking Adiff Gel . Do not apply Adiff Gel in large amounts or use it for a longer time than prescribed, as it does not give quick or better results but increases the risk of side effects such as irritation, scaling, or redness of the skin. If you have eczema (itchy, swollen, rough, and cracked skin) or sunburned skin, please inform your doctor before taking Adiff Gel .

Uses of Adiff Gel

Treatment of Acne (pimples).

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Wash the affected area with water and dry it thoroughly. Apply a thin layer of Adiff Gel to the clean, dry skin at night before bedtime, or as directed by your doctor.• Adiff Gel is for external use only. Wash your hands before and after applying Adiff Gel .

Medicinal Benefits

Adiff Gel contains Adapalene (man-made vitamin A), which is used to treat acne (pimples). Adiff Gel loosens the cells on the skin’s surface and unblocks pores by reducing the production of oil in the skin. Thus, it decreases pimples, spots, whiteheads, and blackheads. Also, Adiff Gel increases the production of new skin cells and helps in natural exfoliation (removal of dead skin cells) of the outer layers of the skin. Adiff Gel has an anti-inflammatory effect and thus reduces irritation and soreness.

How Adiff Gel Works

Adiff Gel contains Adapalene, which works by loosening the cells on the skin’s surface and unblocking pores by reducing oil production. Thus, it decreases pimples, whiteheads, and blackheads.

Storage

Keep Adiff Gel out of reach and sight of children.
Side effects of Adiff Gel 15 gm
  • After taking a shower or bath, apply a moisturizer to damp skin.
  • Use petroleum jelly or other thick emollients.
  • Use a hypoallergenic, fragrance-free moisturizer 2 to 3 times a day or as frequently as required.
  • Exfoliate your skin gently using a pumice stone or slightly abrasive sponge.
  • Do not scrub your skin.
  • Avoid hot showers or baths. Instead take short, warm showers or baths.
  • Use mild soap or skin cleansers with added moisturizer.
  • Drink lots of water.
  • Use sunscreen and wear protective clothing while going out to protect yourself from sun damage.
Here are the steps to manage medication-triggered Burning Or Stinging:
  • If you experience burning or stinging sensations and suspect that they may be related to medication, consult a doctor or healthcare expert to determine the cause and best course of treatment.
  • Avoid harsh products, extreme temperatures, and other potential irritants that may exacerbate burning or stinging.
  • Your healthcare professional may recommend applying a soothing or protective agent, such as a cream, gel, or ointment, to help alleviate burning or stinging.
  • Follow your healthcare professional's advice on how to care for the affected area, as gentle cleaning and care instructions may vary depending on the location and severity of the burning or stinging.
  • Schedule follow-up appointments with your doctor to monitor your symptoms and adjust your treatment plan as needed. If the burning or irritation persists or worsens, seek medical attention.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Avoid extreme heat or cold, like hot showers or cold winds, to prevent worsening skin discomfort.
  • Cool compresses: To reduce itch, redness, and swelling.
  • Avoid irritants like harsh chemicals or allergens to prevent worsening skin discomfort.
  • If you have severe itching, burning, or blistering seek medical attention.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Sunburns can occur commonly. Cover the area that is affected to avoid extended exposure.
  • Apply a clean, dampened towel to the affected skin for relief.
  • Take a cool bath by adding baking soda to water.
  • Sleep well and give enough rest to your body.
  • Take a balanced diet that heals the allergy or burns.
  • Apply a skin-calming lotion, gel or moisturiser frequently.
  • Apply moisturizer immediately after showering or bathing.
  • Use a moisturizer containing lanolin, petroleum jelly, glycerine, hyaluronic acid or jojoba oil.
  • Do not use hot water for bathing. Instead use warm water and limit showers and bath to 5 to 10 minutes.
  • Apply a sunscreen with SPF-30 or higher.
  • Avoid harsh soaps, detergents and perfumes.
  • Do not scratch or rub the skin.
  • Drink adequate water to prevent dehydration.
  • Wear pants, full sleeves and a wide-brimmed hat while going out in the sun.

What if I have taken an overdose of Adiff Gel

Do not apply Adiff Gel in large amounts or use it for a long time than recommended, as it does not give quick or better results but may result in overdose. The symptoms of overdose include skin irritation, scaling and redness. If you suspect you have used more or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you are known to be allergic to Adiff Gel or any other medicines, please tell your doctor. Do not apply Adiff Gel on cuts, open wounds, scrapes, sunburned, windburned, chapped, dry, or irritated skin. Avoid contact of Adiff Gel with nose, ears, mouth, or eyes. In case Adiff Gel comes in contact with these areas accidentally, rinse with warm water thoroughly. Avoid exposure to tanning beds or sunlight while using Adiff Gel as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you are pregnant or breastfeeding, please inform your doctor before taking Adiff Gel . Do not apply Adiff Gel in large amounts or use for a long time than prescribed as it does not give quick or better results but increases the risk of side effects such as irritation, scaling, or redness of the skin. You are advised not to use other acne products containing erythromycin, benzoyl peroxide, or clindamycin with Adiff Gel at the same time as it may cause excessive irritation or dry skin. Therefore, it is recommended to use Adiff Gel at night and other products in the morning. If you have eczema (itchy, swollen, rough, and cracked skin) or sunburned skin, please inform your doctor before taking Adiff Gel .

Drug-Drug Interactions

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Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid sun exposure while using Adiff Gel as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.

  • Regular exercise can improve your mood and self-esteem though it doesn’t clear acne. Take a shower immediately after finishing exercise as sweat may irritate acne.

  • Do regular hair wash regularly and avoid hair falling across the face.

  • Remove the make-up completely before going to bed.

  • Avoid using products that may cause skin irritation such as harsh soaps, skin cleansers, shampoos, hair removers or waxes, hair colouring or permanent chemicals, detergents, and rough fabrics.

Habit Forming

No

Therapeutic Class

RETINOIDS

Adiff Gel Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

The interaction of Adiff Gel with alcohol is unknown. Please consult a doctor before consuming alcohol while using Adiff Gel .

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Pregnancy

Unsafe

Adiff Gel is a category C pregnancy drug and is usually not recommended for pregnant women. Please consult a doctor if you are pregnant.

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Breast Feeding

Caution

It is unknown whether Adiff Gel is excreted in human milk. Therefore, Adiff Gel is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. However, do not apply Adiff Gel on the chest area to avoid the contact of Adiff Gel with the baby.

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Driving

Safe if prescribed

Adiff Gel usually does not affect your ability to drive or operate machinery.

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Liver

Safe if prescribed

If you have any concerns regarding the use of Adiff Gel in patients with Liver problems, please consult a doctor.

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Kidney

Safe if prescribed

If you have any concerns regarding the use of Adiff Gel in patients with kidney problems, please consult a doctor.

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Children

Unsafe

Adiff Gel is not recommended for children below 12 years as the safety and effectiveness were not established.

Have a query?

FAQs

Adiff Gel is used to treat acne, a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil.

Adiff Gel works by loosening the cells on the skin’s surface and unblocks pores by reducing the production of oil in the skin. Thereby, decreases pimples, spots, whiteheads and blackheads. Also, adapalene increases the production of new skin cells and helps in natural exfoliation (removal of dead skin cells) of the outer layers of the skin.

Adiff Gel may cause photosensitivity (increased skin sensitivity to sunlight) in the treated areas. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen (SPF 30 or more) and wear protective clothing while going out to prevent sunburn.

No, Adiff Gel is not recommended for eczema (itchy, cracked, swollen or rough skin) patients as it may cause severe irritation. Therefore, if you are suffering from eczema, inform your doctor before using Adiff Gel .

Yes, Adiff Gel may cause skin irritation as a side effect. However, if the irritation persists or worsens, stop using Adiff Gel and consult a doctor.

You are advised not to use other acne products containing erythromycin, benzoyl peroxide or clindamycin with Adiff Gel at the same time as it may cause excessive irritation or dry skin. Therefore, it is recommended to use Adiff Gel at night and other products in the morning. However, please consult a doctor before using any other medicines or products with Adiff Gel .

Yes, Adiff Gel may cause dryness of the skin. You can use a moisturizer while using Adiff Gel to prevent dry skin. However, do not apply Adiff Gel and moisturizer at the same time as it may reduce the effectiveness of Adiff Gel . Please consult a doctor before using other products with Adiff Gel .

Adiff Gel may cause side effects such as skin irritation, skin redness, burning sensation of the skin, sun burn, skin peeling or dry skin. If these side effects persist or worsen, please consult your doctor.

Yes, Adiff Gel helps in reducing the scars after acne.

Blackheads are type of acne only. Thus, Adiff Gel can be used to manage and treat acne. However, it is advised to use Adiff Gel only after the doctors advise. The doctor will prescribe you the same after proper skin diagnosis. Do not self-medicate.

Adiff Gel is usually not recommended for pregnant women. Please consult a doctor if you are pregnant.

It is advisable to avoid cosmetic procedures while using Adiff Gel . As, the cosmetic products with an abrasive, peeling or drying action may increase irritant effect. Please consult your doctor if you have any concerns regarding this.

Yes, Adiff Gel may cause burning sensation as a common side effect. Also, during the first 4 weeks of treatment, you may experience drying, redness, and scaling which usually reduce as you continue to use Adiff Gel . If the side effects persist or worsen, inform your doctor.

You may start to see improvement after using Adiff Gel for two weeks, but it may take a minimum of eight weeks to notice consistent beneficial effects.

If necessary, moisturizers may be used; however, products containing glycolic or alpha hydroxy acids should be avoided.

Adiff Gel should be applied at night before bedtime or should be used as advised by your doctor. Clean the affected area with water and ensure it is dry before applying Adiff Gel . Apply it as a thin layer over the entire face and any other affected areas by taking a small amount onto your fingertips. It is important to clean your hands after applying Adiff Gel .

Avoid contact of Adiff Gel with the lips, eyes, angles of the nose, and inside of the mouth. Do not apply Adiff Gel on abrasions, cuts, reddened or inflamed skin, and sunburned skin. Wax epilation should be avoided on treated skin, as it may cause skin erosions.

You are advised to limit your time outside in the sun as Adiff Gel makes skin sensitive. If you must be in sunlight, you should wear sunscreen and wear a hat and clothes that cover the treated areas. You should avoid weather extremes such as cold and wind, as this may irritate your skin. Avoid using some skin products, such as astringents, harsh soaps, cosmetics that have strong skin-drying effects. In addition, products with high alcohol levels should be avoided, as they may further irritate or dry your skin.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Other Info - ADI0013

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:41 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.920.pdf
  2. https://www.drugs.com/mtm/adapalene-topical.html

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