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compositionComposition:ADENOSINE-30MG
prescription
Prescription Medicine
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ADENOJECT INJECTION is an antiarrhythmic medication used to address a condition known as paroxysmal supraventricular tachycardia. (Including a condition called Wolff-Parkinson-White syndrome). This is when the heart pulses too quickly. ADENOJECT INJECTION works by slowing down the electrical impulses that regulate the heart rhythm. This enables the heart rhythm to return to normal. Aside from that, ADENOJECT INJECTION is used to help doctors comprehend how your heart works.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ADENOSINE-30MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About ADENOJECT INJECTION

ADENOJECT INJECTION is a prescription injection used to quickly restore a normal, steady rhythm in patients experiencing certain types of rapid heartbeats, specifically paroxysmal supraventricular tachycardia (PSVT). It is also utilised during certain heart imaging tests to help doctors evaluate blood flow to the heart muscle. Because of how quickly it works, this medicine is only given under close medical supervision.

Since ADENOJECT INJECTION is given as a single rapid injection or a short infusion during a medical emergency or a specific diagnostic test, it does not require a regular daily dosing schedule. You do not need to worry about taking it with food, but avoiding caffeine and certain lifestyle triggers like smoking or heavy physical stress can help manage underlying heart rhythm issues.

Most people experience brief side effects during the injection, such as a feeling of warmth (flushing), shortness of breath, or chest pressure, which usually pass within a minute. However, you should immediately inform the medical team if you experience severe chest pain, extreme dizziness, or difficulty breathing that does not go away quickly.

Before receiving ADENOJECT INJECTION, tell the healthcare provider if you have a history of asthma, severe lung disease, or certain types of irregular heartbeats like a slow heart rate or heart block. Do not receive this medicine if you have certain advanced heart block conditions without a working pacemaker, or if you have severe breathing disorders.

Certain substances, such as caffeine, tea, and medications containing theophylline, can block the effects of ADENOJECT INJECTION, while others like dipyridamole can make it much stronger. It is also important to tell your doctor if you are pregnant, breastfeeding, or are an older adult, as they will need to carefully monitor your response.

Uses of ADENOJECT INJECTION

ADENOJECT INJECTION helps restore a normal heart rhythm and is also used during certain heart imaging procedures. Your doctor may prescribe it for the following conditions:

  • Rapid heart rate (Paroxysmal Supraventricular Tachycardia): ADENOJECT INJECTION helps by slowing down the electrical signals in the heart to quickly restore a normal, steady heartbeat during sudden episodes of rapid heartbeats.
  • Heart imaging tests (Myocardial Perfusion Scintigraphy): For patients who cannot exercise on a treadmill, ADENOJECT INJECTION is used during a stress test to temporarily mimic the effects of exercise on the heart, allowing doctors to check the blood flow to your heart muscles.

Key Benefits

Using ADENOJECT INJECTION as prescribed helps restore a normal heart rhythm or supports important heart imaging tests. Here are the key benefits you can expect:

  • Rapidly restores a normal heart rhythm: ADENOJECT INJECTION works within seconds to slow abnormal electrical signals in the heart, helping relieve episodes of rapid heart rate.
  • Relieves distressing symptoms: It helps reduce symptoms such as a racing heartbeat, chest fluttering, palpitations, and the anxiety associated with sudden episodes of fast heart rate.
  • Supports accurate heart testing: During myocardial perfusion scintigraphy, ADENOJECT INJECTION safely mimics the effects of exercise, allowing doctors to evaluate blood flow to the heart in people who cannot exercise adequately.
  • Provides a non-exercise alternative: It enables patients with mobility limitations or other physical restrictions to undergo essential cardiac stress testing without strenuous physical activity.
Side effects of Adenoject Injection 10ml
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • ADENOJECT INJECTION will be administered by the doctor or healthcare professional in a medical setting.
  • Do not self-administer.

How ADENOJECT INJECTION Works

ADENOJECT INJECTION contains adenosine, an antiarrhythmic medicine that helps restore a normal heart rhythm during certain types of rapid heartbeat. ADENOJECT INJECTION works by temporarily slowing electrical conduction through the atrioventricular (AV) node, a key part of the heart's electrical system. This briefly interrupts the abnormal electrical signals responsible for paroxysmal supraventricular tachycardia (PSVT), allowing the heart's normal rhythm to resume. ADENOJECT INJECTION has a very short duration of action and is rapidly cleared from the bloodstream within seconds. During cardiac stress testing, it also widens the coronary blood vessels, increasing blood flow to help doctors assess blood supply to the heart muscle.
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Alcohol

Caution

Consuming alcohol while on treatment with ADENOJECT INJECTION is not advisable as it may cause serious side effects.

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Pregnancy

Caution

It is not known whether ADENOJECT INJECTION can cause foetal harm if taken during pregnancy. It should be taken if clearly needed. If you are pregnant, inform your doctor. Your doctor will weigh the benefits and potential risks before prescribing ADENOJECT INJECTION.

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Breast Feeding

Caution

It is unknown if ADENOJECT INJECTION passes into breastmilk. Inform your doctor if you are breastfeeding; your doctor will decide whether ADENOJECT INJECTION can be taken by breastfeeding mothers or not.

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Driving

Caution

ADENOJECT INJECTION causes drowsiness and dizziness, so drive only if alert while on treatment with this medicine.

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Liver

Safe if prescribed

It is generally safe to be taken ADENOJECT INJECTION if you have liver problems. However, If you have a history of liver diseases, inform your doctor before receiving this injection.

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Kidney

Safe if prescribed

It is generally safe to be taken ADENOJECT INJECTION if you have kidney problems. However, If you have a history of kidney diseases, inform your doctor before receiving this injection.

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Children

Caution

There are no controlled studies on the use of ADENOJECT INJECTION in children. Please consult your doctor if your child has PSVT.

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Heart

Safe if prescribed

ADENOJECT INJECTION is used to treat certain heart rhythm disorders but must be given under strict medical supervision. It may trigger serious cardiac effects in unstable heart conditions, so specialist evaluation is essential.

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Geriatrics

Safe if prescribed

Geriatric patients may receive ADENOJECT INJECTION, but only under strict medical supervision. Age-related heart sensitivity and slower drug clearance demand careful monitoring during administration.

What if I have taken an overdose of ADENOJECT INJECTION

An overdose of ADENOJECT INJECTION is extremely unlikely because it is given by trained medical professionals under strict monitoring. However, because the drug is cleared from the body within seconds, any temporary effects of an overdose are typically managed immediately by the healthcare team in the clinical setting.

Diet & Lifestyle Advise

  • Avoid Caffeine Before the Procedure: Do not consume coffee, tea, cola, energy drinks, chocolate, or other sources of caffeine for 12–24 hours before receiving ADENOJECT INJECTION, as caffeine can reduce or block its effects.
  • Avoid Smoking and Nicotine: Do not smoke or use nicotine products before your procedure, as they may interfere with heart rate measurements and blood flow assessment.
  • Manage Stress: Practise stress-reducing techniques such as deep breathing, meditation, or gentle yoga, as emotional stress can trigger episodes of rapid heart rate.
  • Stay Hydrated: Drink enough water unless your doctor has advised you to limit fluid intake because of a heart condition or another medical problem.
health query

Have a query?

How Soon It Starts Working

The time required for ADENOJECT INJECTION to start to work: ADENOJECT INJECTION ideally shows its action within 20 to 30 seconds after administration. The time for which the effects of ADENOJECT INJECTION last: The effect of ADENOJECT INJECTION lasts for 10 to 30 seconds.

What if you forget to take ADENOJECT INJECTION

Since this medication is given in a clinical setting by a healthcare professional during an emergency or diagnostic test, missing a dose is not typical. If a dose is delayed or missed during a procedure, the medical team will adjust the treatment schedule immediately.

Storage

• Store ADENOJECT INJECTION at 15°C to 30°C in its original packaging to protect it from light.

Drug Warnings

  • Inspect the Solution: Ensure the solution is clear, colourless, and free from visible particles before it is administered. Do not use the vial if it appears cloudy, discoloured, or contains particles.
  • Continuous ECG Monitoring: Your heart rhythm should be continuously monitored with an electrocardiogram (ECG) during administration to ensure the medicine is working safely.
  • Check for Crystals: If crystals have formed because the vial was accidentally cooled, the solution should be allowed to return to room temperature until the crystals dissolve completely. Do not use the vial if the crystals remain.
  • Inform Your Doctor About Lung Conditions: Tell your doctor if you have asthma, chronic obstructive pulmonary disease (COPD), or other breathing disorders, as ADENOJECT INJECTION may temporarily narrow the airways.
  • Report Any Symptoms During Injection: Temporary flushing, chest tightness, shortness of breath, or a feeling of pressure may occur during the injection and usually resolve within a minute. Inform your healthcare team immediately about any symptoms you experience.

Drug-Drug Interactions

verifiedApollotooltip
  • Theophylline or Aminophylline: May decrease the effectiveness of ADENOJECT INJECTION, meaning a higher dose of the injection might be required.
  • Dipyridamole: May significantly increase the effects of ADENOJECT INJECTION on the heart, requiring your doctor to adjust your dose or monitor you even more closely.
  • Carbamazepine: May increase the risk of developing a severe slow heart rate or heart block when combined with ADENOJECT INJECTION.
AdenosineDigoxin
Severe
AdenosineHaloperidol
Severe

Drug-Drug Interactions

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AdenosineDigoxin
Severe
How does the drug interact with Adenoject Injection 10ml:
Co-administration of Adenoject Injection 10ml with Digoxin shows additive effects on the heart and may cause abnormal heart rhythms.

How to manage the interaction:
Taking Adenoject Injection 10ml with Digoxin together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, difficulty in breathing, or chest pain. Do not discontinue any medications without consulting a doctor.
AdenosineHaloperidol
Severe
How does the drug interact with Adenoject Injection 10ml:
Coadministration of Adenoject Injection 10ml with Haloperidol can increase the risk of developing irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Adenoject Injection 10ml with Haloperidol together can result in an interaction, but it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, difficulty breathing, shortness of breath or chest pain. Do not discontinue any medications without consulting a doctor.
AdenosinePapaverine
Severe
How does the drug interact with Adenoject Injection 10ml:
Concomitant use of Adenoject Injection 10ml with Papaverine can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Adenoject Injection 10ml with Papaverine together can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, difficulty in breathing, palpitations, or chest pain. Do not discontinue any medications without a consulting a doctor.
AdenosineArsenic trioxide
Severe
How does the drug interact with Adenoject Injection 10ml:
Using arsenic trioxide with Adenoject Injection 10ml can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
There may be a possibility of interaction between Arsenic trioxide and Adenoject Injection 10ml, but it can be taken if prescribed by a doctor. Call a doctor right away if you have symptoms like palpitations, shortness of breath, or chest discomfort. Do not discontinue any medications without consulting a doctor.
AdenosineCabozantinib
Severe
How does the drug interact with Adenoject Injection 10ml:
Using cabozantinib with Adenoject Injection 10ml can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Adenoject Injection 10ml with Cabozantinib together can result in an interaction, but it can be taken if your doctor has advised it. If you experience palpitations, shortness of breath, chest discomfort, or dizziness, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AdenosineGatifloxacin
Severe
How does the drug interact with Adenoject Injection 10ml:
Concomitant use of Adenoject Injection 10ml with Gatifloxacin can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Adenoject Injection 10ml with Gatifloxacin together can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, difficulty in breathing, or chest pain. Do not discontinue any medications without consulting a doctor.
AdenosineMethadone
Severe
How does the drug interact with Adenoject Injection 10ml:
Concomitant use of Adenoject Injection 10ml with Methadone can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Adenoject Injection 10ml with Methadone together can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as palpitations, dizziness, difficulty in breathing, or chest pain. Do not discontinue any medications without consulting a doctor.
AdenosineIbutilide
Severe
How does the drug interact with Adenoject Injection 10ml:
Using ibutilide Adenoject Injection 10ml can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Co-administration of Adenoject Injection 10ml with Ibutilide can result in an interaction, but it can be taken if your doctor has advised it. If you experience shortness of breath, palpitations, or chest discomfort, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
AdenosineBedaquiline
Severe
How does the drug interact with Adenoject Injection 10ml:
Concomitant use of Adenoject Injection 10ml with Bedaquiline can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Adenoject Injection 10ml and Bedaquiline can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, difficulty in breathing, palpitations, or chest pain. Do not discontinue any medications without consulting a doctor.
AdenosineEfavirenz
Severe
How does the drug interact with Adenoject Injection 10ml:
Concomitant use of Adenoject Injection 10ml with Efavirenz can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Adenoject Injection 10ml with Efavirenz together can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, difficulty in breathing, or chest pain. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

  • Caffeine (coffee, tea, soda, chocolate): May block the active receptors in your body, preventing ADENOJECT INJECTION from working effectively. Avoid these for 12 to 24 hours before your dose.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIARRHYTHMICS]

FAQs

ADENOJECT INJECTION is used to treat Paroxysmal supraventricular tachycardia.
ADENOJECT INJECTION contains adenosine, which works by slowing down the electrical impulses which control the heart rhythm. This allows the heart rhythm to return to normal.
ADENOJECT INJECTION is contraindicated to use in a population with severely low blood pressure. So, people with severely low blood pressure should not take ADENOJECT INJECTION.
ADENOJECT INJECTION may cause unusual skin sensations such as reddening (with a feeling of heat) and burning sensations. In most cases, these side effects gradually resolve over time. However, if these persist or worsen, reach out to your doctor.
ADENOJECT INJECTION may lower blood pressure. If this condition persists for a longer duration or if you already have low blood pressure, inform your doctor.
While taking ADENOJECT INJECTION, it is important to monitor your heart rate, blood pressure, breathing, and oxygen levels. Your doctor will provide specific guidance on what to monitor based on your health conditions.
ADENOJECT INJECTION is administered by a qualified healthcare professional, directly into one of your veins. ADENOJECT INJECTION is given rapidly over 2 seconds, to quickly slow down the heart rate and restore a normal heart rhythm. Do not self-administer.
The side effects of ADENOJECT INJECTION include facial flushing, dyspnea (shortness of breath), chest pressure, and nausea. These side effects start immediately after ADENOJECT INJECTION is given and usually last less than one minute. Please, contact a doctor if these continue longer.
A feeling of chest tightness, pressure, or shortness of breath is a common and expected side effect of ADENOJECT INJECTION. This occurs because the medicine temporarily slows down the heart's electrical signals and can mildly constrict the airways. These sensations are brief and usually disappear completely within 60 seconds. Talk to your doctor or nurse if you feel severe discomfort.
You must inform your medical team if you have asthma or any other lung disease before receiving ADENOJECT INJECTION. This medicine can cause your airways to tighten temporarily, which may trigger an asthma attack. In some cases, your doctor may choose an alternative treatment. Talk to your doctor to see if this medicine is safe for you.
Yes, you must avoid coffee, tea, energy drinks, chocolate, and any other caffeine-containing foods or beverages for at least 12 to 24 hours before receiving ADENOJECT INJECTION. Caffeine directly blocks the action of this medicine and can make it ineffective. Talk to your doctor or pharmacist about how to prepare for your procedure.
ADENOJECT INJECTION is generally used in emergencies or specific diagnostic situations, and its safety during pregnancy must be carefully weighed by your doctor. Because it stays in the body for only a few seconds, it is often preferred in emergencies, but you should always inform your healthcare provider if you are pregnant or breastfeeding. Talk to your doctor for personalised advice.
ADENOJECT INJECTION temporarily slows or pauses the electrical conduction in the heart for a few seconds to "reset" an abnormally fast rhythm back to normal. While this can feel unusual, it is a controlled medical effect, and your heart's natural pacemaker typically resumes a normal rhythm almost immediately. This procedure is always performed under continuous ECG monitoring. Talk to your doctor if you have concerns about this process.
No, ADENOJECT INJECTION does not have long-term side effects because the body clears it completely within seconds of injection. Any side effects you feel, such as flushing, headache, or dizziness, will typically resolve within a couple of minutes after the injection is completed. Talk to your doctor if you experience any lingering symptoms.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - ADE0005
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