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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Adbiron 500 mg Tablet 60's is used in combination with prednisone or prednisolone to treat prostate cancer in adult men that has spread to other body parts. It contains Abiraterone, which works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer. It is not for use in women, children, and adolescents. In some cases, Adbiron 500 mg Tablet 60's may cause common side effects such as diarrhoea, urinary tract infection, high blood pressure, low blood potassium, and oedema. If any of the side effects persist or worsen, consult your doctor.

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Whats That

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Synonym :

ABIRATERONE ACETATE

Composition :

ABIRATERONE-500Mg

Manufacturer/Marketer :

Adley Formulations

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Adbiron 500 mg Tablet 60's

Adbiron 500 mg Tablet 60's belongs to the group of medicines called androgen biosynthesis inhibitors that is indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts.

Adbiron 500 mg Tablet 60's contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.

In some cases, Adbiron 500 mg Tablet 60's may cause common side effects such as diarrhoea, urinary tract infection, high blood pressure, low blood potassium, and oedema. If any of the side effects persist or worsen, consult your doctor.

Adbiron 500 mg Tablet 60's is not for use in women, children, and adolescents. Adbiron 500 mg Tablet 60's should not be given in combination with Ra-233 (a radioactive isotope used to treat prostate cancer) due to the increased risk of bone fracture or death. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Adbiron 500 mg Tablet 60's

Adbiron 500 mg Tablet 60's is used in the treatment of prostate cancer. The detailed uses of Adbiron 500 mg Tablet 60's are as follows:<br/>• Treats advanced prostate cancer: Adbiron 500 mg Tablet 60's lowers levels of certain hormones (androgens) that fuel the growth of prostate cancer cells.<br/>• Slows cancer progression: Adbiron 500 mg Tablet 60's helps delay the spread and worsening of prostate cancer.<br/>• Improves overall management of prostate cancer: Adbiron 500 mg Tablet 60's is often used along with other medicines to enhance treatment effectiveness.<br/>

Directions for Use

• Adbiron 500 mg Tablet 60's can be taken on an empty stomach, i.e., 1 hour before or 2 hours after food. • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Swallow Adbiron 500 mg Tablet 60's as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

Adbiron 500 mg Tablet 60's belongs to the group of medicines called androgen biosynthesis inhibitors, indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts. Adbiron 500 mg Tablet 60's contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer. It is indicated in patients with metastatic castration-resistant prostate cancer (CRPC) who have received prior chemotherapy containing docetaxel and metastatic high-risk castration-sensitive prostate cancer (CSPC). Adbiron 500 mg Tablet 60's is prescribed in the early stages of the disease, where it is still responding to hormone therapy. It is used with androgen deprivation therapy (a treatment that lowers testosterone).

How Adbiron 500 mg Tablet 60's Works

Adbiron 500 mg Tablet 60's contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Adbiron 500 mg Tablet 60's out of sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Adbiron Tab
  • If you have discomfort, illness, or unease after taking medication, seek medical attention.
  • Your treatment plan may be modified, including adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage discomfort, follow your doctor's advice, like getting plenty of rest, or staying hydrated, and practising stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to manage the discomfort effectively.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

What if I have taken an overdose of Adbiron 500 mg Tablet 60's

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Adbiron 500 mg Tablet 60's may include fast or irregular heartbeat, lightheadedness, dizziness, or fainting, shortness of breath or difficulty breathing, swelling of the feet, ankles, or lower legs, and unexplained weight gain. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Do not take Adbiron 500 mg Tablet 60's if you are allergic to any of its components, if you have severe liver damage, or in combination with Ra-233 (used to treat prostate cancer). Inform your doctor if you have liver problems, high blood pressure, low blood potassium, heart failure, heart or blood vessel problems, irregular or rapid heartbeat, heart rhythm problems, shortness of breath, rapid weight gain, swelling in the legs, ankles, or feet, high blood sugar, bone problems, or if you have taken ketoconazole in the past for prostate cancer. Adbiron 500 mg Tablet 60's may cause libido (decreased sex drive), muscle weakness, decreased red blood cells, and/or muscle pain. Adbiron 500 mg Tablet 60's should not be given in combination with Ra-233 due to an increased risk of bone fracture or death.

Drug-Drug Interactions

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AbirateroneEliglustat
Critical

Drug-Drug Interactions

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How does the drug interact with Adbiron Tab:
Taking Adbiron Tab with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Adbiron Tab and Thioridazine together is not recommended and can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneEliglustat
Critical
How does the drug interact with Adbiron Tab:
Coadministration of Adbiron Tab with Eliglustat can increase the levels of Eliglustat in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Adbiron Tab with Eliglustat is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AbirateroneMesoridazine
Critical
How does the drug interact with Adbiron Tab:
Taking Adbiron Tab with Mesoridazine can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Adbiron Tab and Mesoridazine together is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Adbiron Tab:
Taking Adbiron Tab with ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Adbiron Tab and ziprasidone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
AbirateroneSaquinavir
Critical
How does the drug interact with Adbiron Tab:
Taking Adbiron Tab with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Adbiron Tab and Saquinavir together is not recommended as it can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneMethadone
Severe
How does the drug interact with Adbiron Tab:
Taking Adbiron Tab with Methadone can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Adbiron Tab and Methadone together can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat Do not discontinue any medications without consulting a doctor.
How does the drug interact with Adbiron Tab:
Taking Adbiron Tab with Sparfloxacin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Adbiron Tab and Sparfloxacin together can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneOxycodone
Severe
How does the drug interact with Adbiron Tab:
Coadministration of Adbiron Tab with Oxycodone can increase the levels of Oxycodone in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Adbiron Tab with Oxycodone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, fainting, confusion, excessive drowsiness, slow heart rate, and/or shallow or difficult breathing, contact a doctor immediately. Avoid activities requiring mental alertness such as driving or operating hazardous machinery while taking these medications. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Adbiron Tab:
Phenobarbital can drastically lower Adbiron Tab levels in the blood, which can lead to low treatment outcomes.

How to manage the interaction:
Although taking phenobarbital with Adbiron Tab can lead to interaction, it can be taken if recommended by a doctor. If you experience any symptoms, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Adbiron Tab:
Using escitalopram together with Adbiron Tab can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Escitalopram with Adbiron Tab can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience dizziness, irregular heartbeat, drowsiness, lightheadedness, shortness of breath, vomiting, or shortness of breath, consult a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS
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Alcohol

Consult your doctor

It is unknown if alcohol affects Adbiron 500 mg Tablet 60's. Please consult your doctor.

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Pregnancy

Unsafe

Adbiron 500 mg Tablet 60's is not for use in women.

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Breast Feeding

Not applicable

Adbiron 500 mg Tablet 60's is not for use in women.

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Driving

Safe if prescribed

Adbiron 500 mg Tablet 60's is not likely to affect your ability to drive or operate machinery.

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Liver

Caution

Do not take Adbiron 500 mg Tablet 60's if you have severe liver damage. Please consult your doctor if you have a liver impairment or any concerns.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns.

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Children

Not applicable

Adbiron 500 mg Tablet 60's is not for use in children and adolescents.

Have a query?

FAQs

Adbiron 500 mg Tablet 60's is used to treat Prostate cancer.

Adbiron 500 mg Tablet 60's works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.

Prednisolone/prednisone is prescribed along with Adbiron 500 mg Tablet 60's to lower the chances of getting high blood pressure, fluid retention (having too much water in the body), or low blood potassium levels.

Adbiron 500 mg Tablet 60's should not be given along with Ra-233 (a radioactive isotope used to treat prostate cancer) due to the increased risk of bone fracture or death. If you are prescribed to take Ra-233 following treatment with Adbiron 500 mg Tablet 60's and prednisolone/prednisone, you must wait five days before starting treatment with Ra-233.

No, Adbiron 500 mg Tablet 60's cannot cure prostate cancer. However, it is used to manage advanced or metastatic prostate cancer that works by inhibiting the production of testosterone, thereby preventing the growth and spread of cancer.

No, Adbiron 500 mg Tablet 60's is not a chemotherapy drug. It is a hormone therapy medication, which reduces testosterone levels to help manage prostate cancer.

Yes, Adbiron 500 mg Tablet 60's may affect the liver. Therefore, the doctor may advise regular blood tests to monitor its effects on the liver.

For patients taking Adbiron 500 mg Tablet 60's liver investigations are recommended. However, the frequency may differ for each individual and can be determined by the doctor based on your medical condition.

Adbiron 500 mg Tablet 60's can be taken orally on an empty stomach, either 1 hour before a meal or 2 hours after the meal. Swallow it as a whole with a glass of water. Do not chew or break it.

The side effects of Adbiron 500 mg Tablet 60's include oedema, urinary tract infection, high blood pressure, low blood potassium, and diarrhoea. Consult the doctor if any of these symptoms persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Sco- 42, Sector 12, Panchkula-134112, Haryana, India
Other Info - ADB0040

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