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compositionComposition:ADALIMUMAB-20MG
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Prescription Medicine
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Adalirel 20mg Injection is used to help reduce signs and symptoms of autoimmune disorders such as Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis, Crohn's disease, Uveitis and Ulcerative colitis. It consists of Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

ADALIMUMAB-20MG

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Adalirel 20mg Injection

Adalirel 20mg Injection is an injectable prescription medicine used to reduce chronic inflammation in the body. It is clinically approved to treat several autoimmune conditions, including rheumatoid arthritis, plaque psoriasis, Crohn's disease, and ulcerative colitis. By targeting the source of swelling and pain, this medicine helps manage symptoms and prevent further tissue damage.

For best results, you must inject Adalirel 20mg Injection consistently on the schedule prescribed by your doctor. Because it is given as a subcutaneous injection, you can take it with or without food. To support your treatment, incorporating lifestyle changes such as a nutrient-dense diet and low-impact exercise can help manage your symptoms and improve overall mobility.

While using Adalirel 20mg Injection, you may experience mild side effects, such as pain or redness at the injection site, headache, or cold symptoms. However, you must contact your doctor immediately if you experience serious side effects, including signs of infection like a high fever, severe skin rashes, or yellowing of the skin or eyes.

Before starting treatment, tell your doctor if you have a history of tuberculosis, frequent infections, heart failure, or nervous system disorders. Do not take this medicine if you currently have a severe active infection. Your doctor will run blood tests to ensure it is safe for you to start.

This medicine can interact with other treatments, such as live vaccines and other biologic drugs, which can increase your risk of severe infections. It is also important to talk to your doctor or pharmacist if you are pregnant, breastfeeding, or are an older adult, as special precautions may be needed.

Uses of Adalirel 20mg Injection

Adalirel 20mg Injection is used to treat autoimmune and inflammatory conditions. Your doctor may prescribe it for the following conditions:

  • Rheumatoid arthritis: Adalirel 20mg Injection helps reduce joint pain, stiffness, and swelling in adults with moderate to severe rheumatoid arthritis, helping to prevent joint damage.
  • Plaque psoriasis: It is used to treat moderate to severe plaque psoriasis by reducing itchy, scaly skin patches and improving overall skin appearance.
  • Crohn's disease: This medicine reduces inflammation in the digestive tract, helping to control symptoms like abdominal pain and chronic diarrhea.
  • Ulcerative colitis: It helps control inflammation in the large intestine, allowing the bowel lining to heal and helping to achieve long-term remission.
  • Ankylosing spondylitis: It helps reduce inflammation in the spine and joints, easing back pain and improving physical flexibility.

Key Benefits

Using Adalirel 20mg Injection as prescribed helps reduce inflammation and improve symptoms of autoimmune and inflammatory conditions. Here are the key benefits you can expect:

  • Relieves pain and inflammation: Helps reduce joint pain, stiffness, and swelling, making everyday movements more comfortable.
  • Supports digestive health: Helps heal the lining of the digestive tract, reducing flare-ups, abdominal pain, and improving digestive stability in inflammatory bowel disease.
  • Improves skin health: Helps clear red, scaly skin patches, relieving itching and discomfort associated with plaque psoriasis.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Adalirel 20mg Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Adalirel 20mg Injection Works

Adalirel 20mg Injection contains adalimumab, a monoclonal antibody that helps treat autoimmune and inflammatory conditions. It works by targeting and blocking a protein called tumour necrosis factor (TNF), which plays a key role in causing inflammation. In autoimmune diseases, the body produces too much TNF, leading the immune system to attack healthy tissues. By binding to excess TNF, Adalirel 20mg Injection blocks the inflammatory signals responsible for swelling and tissue damage. This helps reduce inflammation, relieve symptoms, protect joints and other affected tissues, and improve overall disease control.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Adalirel 20mg Injection. Please consult the doctor.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Adalirel 20mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Adalirel 20mg Injection.

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Driving

Caution

Adalirel 20mg Injection will be administered in the hospital setting. Hence, driving is not recommended.

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Liver

Caution

Adalirel 20mg Injection should be used with caution if you have liver disease. Dose adjustment may be needed in patients with liver impairment.

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Kidney

Caution

Adalirel 20mg Injection should be used with caution if you have kidney disease. Dose adjustment may be needed in patients with liver impairment.

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Children

Caution

Adalirel 20mg Injection is not recommended in children below two years of age as safety and efficacy are not established. In children above two years of age, it will be administered by the pediatrician. Adalirel 20mg Injection is used in children only for the treatment of juvenile idiopathic arthritis, paediatric Crohn’s disease, and uveitis.

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Heart

Caution

Adalirel 20mg Injection may not be safe for heart patients. Therefore, please inform your doctor if you have any pre-existing heart conditions.

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Geriatrics

Consult your doctor

Limited information available about the use of Adalirel 20mg Injection in geriatric patients. Please consult your physician.

What if I have taken an overdose of Adalirel 20mg Injection

If you accidentally inject more than your prescribed dose, seek immediate medical attention or call an emergency health service right away, even if you do not feel any symptoms.

Diet & Lifestyle Advise

  • Practice excellent hygiene: Because this medicine lowers your body's ability to fight infections, wash your hands frequently with soap and water, and avoid close contact with people who are sick.
  • Avoid raw or undercooked foods: Protect yourself from foodborne illnesses by avoiding raw meats, raw seafood, and unpasteurized dairy products, as your immune system is less active.
  • Stay active with gentle exercise: If you are treating joint conditions, engage in low-impact physical activities like swimming, cycling, or walking to keep joints flexible and reduce stiffness.
  • Identify food triggers: If you are treating Crohn's disease or ulcerative colitis, keep a food diary to identify foods that trigger flares, and focus on a diet rich in easy-to-digest nutrients.
  • Protect your skin: Wear sunscreen and protective clothing outdoors, as some inflammatory skin conditions can become more sensitive during treatment.
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Have a query?

How Soon It Starts Working

The time required for Adalirel 20mg Injection to start to work: The exact onset of time for Adalirel 20mg Injection is unknown. The time for which the effects of Adalirel 20mg Injection last: The duration of Adalirel 20mg Injection’s effect is clinically not established.

What if you forget to take Adalirel 20mg Injection

If you miss a dose of Adalirel 20mg Injection, inject it as soon as you remember. However, if your next scheduled dose is coming up soon, skip the missed dose and return to your regular schedule. Do not inject a double dose to make up for a missed one. If you are unsure what to do, talk to your doctor or pharmacist.

Storage

• Store Adalirel 20mg Injection in the refrigerator at 2°C–8°C (36°F–46°F) in its original carton to protect it from light.

Drug Warnings

  • Check before use: Inspect the liquid in the syringe or pen before injecting. It should be clear and colourless to pale yellow. Do not use it if it is cloudy, discoloured, or contains visible particles.
  • Do not reuse needles or syringes: Dispose of used needles and syringes immediately in an approved puncture-resistant sharps container.
  • Avoid live vaccines: Do not receive live vaccines, such as live influenza or shingles vaccines, while taking Adalirel 20mg Injection, as they may increase the risk of serious infections.
  • Inform healthcare professionals: Tell your doctor, dentist, surgeon, and other healthcare professionals that you are taking Adalirel 20mg Injection before undergoing any medical or dental procedures.
  • Keep an injection record: Maintain a written log of your injection dates, times, and injection sites to help ensure proper rotation of injection locations.

verifiedApollotooltip
  • Biologic medicines: Taking Adalirel 20mg Injection alongside other biologic drugs (such as abatacept, anakinra, or rituximab) can significantly increase your risk of severe, life-threatening infections.
  • Live vaccines: Combining this medicine with live vaccines can cause active infections from the vaccine virus because your immune response is lowered.

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verifiedApollotooltip
  • No clinically significant food interactions are known with Adalirel 20mg Injection when used as directed.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[IMMUNOSUPPRESSANTS]

FAQs

Adalirel 20mg Injection is used to treat rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis, Crohn's disease, uveitis, and ulcerative colitis. By reducing inflammation, it helps relieve pain, swelling, redness, stiffness, and other symptoms associated with these autoimmune conditions.
Adalirel 20mg Injection contains adalimumab, an antirheumatic medicine belonging to the TNF inhibitor class. It works by blocking TNF-α, a protein that causes inflammation, helping reduce inflammation and symptoms of autoimmune diseases.
Adalirel 20mg Injection affects your immune system and makes you more susceptible to infections. Hence, it is not recommended in people with active infections like tuberculosis or abnormal liver enzymes. Adalirel 20mg Injection can also increase the risk of developing cancers; hence, informing your doctor if you have a history of any cancer is essential.
Treatment with Adalirel 20mg Injection can help reduce inflammation, pain, redness, and swelling associated with various autoimmune disorders.
Adalirel 20mg Injection which contains Adalimumab, can weaken your immune system. Since it affects the immune system, it may increase your risk of developing infections. It is important to follow your doctor's advice and inform them if you have any existing infections or health concerns before starting treatment.
Adalirel 20mg Injection can be used alongside other arthritis medicines such as methotrexate, prednisolone, naproxen, ibuprofen, and paracetamol. However, Adalirel 20mg Injection should not be used with other biological disease-modifying antirheumatic drugs (bDMARDs).
Adalirel 20mg Injection should be stopped before surgery. It can be resumed after the operation, once the wound has healed and there is no infection, as determined by your surgeon and rheumatologist.
Adalirel 20mg Injection causes side effects such as rash, headache, sinusitis, upper respiratory infections, fever, and application site reactions. Therefore, please contact a doctor if these do not reduce and persist for longer durations.
Yes, you can travel with Adalirel 20mg Injection. It can be stored at room temperature up to 77°F (25°C) for up to 14 days, but it must be protected from light and kept from freezing. Talk to your doctor or pharmacist about travel cases and airport security documentation.
Yes, your doctor will perform a tuberculosis (TB) skin or blood test and check for hepatitis B before you start treatment. They will also monitor your blood counts during therapy. Talk to your doctor about these safety tests.
There is no direct interaction between alcohol and Adalirel 20mg Injection. However, alcohol can increase liver strain or trigger flares for conditions like psoriasis or inflammatory bowel disease. Talk to your doctor to see if drinking alcohol is safe for you.
Because Adalirel 20mg Injection lowers your immune response, even a mild cold can sometimes turn into a more serious infection. Contact your doctor immediately if you develop a fever, persistent cough, or cold symptoms, as you may need to pause your injections. Talk to your doctor for guidance.
Yes, you can get the standard injectable flu shot, which is an inactive vaccine. However, you must avoid live vaccines, such as the nasal spray flu vaccine, while on this treatment. Talk to your doctor before scheduling any vaccines.
Adalirel 20mg Injection should only be used during pregnancy or breastfeeding if the benefits outweigh the risks. If you are pregnant, breastfeeding, or planning to have a baby, talk to your doctor to make an informed decision.
No, you should rotate your injection sites with every dose. Injecting into the same spot repeatedly can cause skin thickening, bruising, or pain. Use your abdomen or thighs, and ensure the new spot is at least one inch from the last one. Talk to your doctor or pharmacist if you need help with injection techniques.

Disclaimer

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Country of origin

India
Other Info - AD15990
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