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compositionComposition:QUINAPRIL-5MG
prescription
Prescription Medicine
info
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Acupil 5mg Tablet is primarily used to treat Hypertension. It contains Quinapril, which works by reducing the production of certain substances that cause an increase in blood pressure. This allows the blood to flow more smoothly and makes the heart more efficient at pumping blood throughout the body. Thus, Acupil 5mg Tablet helps reduce high BP and the risk of heart attack, stroke, and angina (chest pain).

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

QUINAPRIL-5MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Acupil 5mg Tablet

Acupil 5mg Tablet is a prescription medication primarily used to treat high blood pressure (hypertension) and to help manage heart failure. By keeping your blood pressure within a healthy range, it helps lower your long-term risk of experiencing serious cardiovascular events like strokes and heart attacks.

This medicine is typically taken once or twice a day, and it is highly important to take it consistently at the same time every day to maintain stable drug levels in your body. You can take this medication with or without food, though eating high-fat meals might slightly reduce how much of the medicine your body absorbs. Adopting a low-sodium diet and engaging in regular moderate exercise can further enhance the positive results of your treatment.

Many patients taking Acupil 5mg Tablet experience only mild side effects, such as a persistent dry cough, headache, or mild dizziness when standing up. However, you must consult your doctor immediately if you face specific serious side effects, such as swelling of your face, lips, tongue, or throat, which can indicate a severe allergic reaction.

Do not take this if you are pregnant, planning to become pregnant, or have a history of severe allergic swelling (angioedema). Talk to your doctor before starting this medicine if you have underlying health conditions such as kidney disease, liver damage, diabetes, or severe dehydration.

This medication can interact with other substances, including certain pain relievers, potassium supplements, and alcohol, which can lead to complications like kidney strain or dangerously low blood pressure. If you are pregnant, breastfeeding, or are an elderly individual, always consult your doctor before starting this treatment to ensure it is safe for your specific situation.

Uses of Acupil 5mg Tablet

Your doctor may prescribe Acupil 5mg Tablet to treat or manage the following conditions:

  • High Blood Pressure (Hypertension): Acupil 5mg Tablet relaxes and widens your blood vessels, which lowers your blood pressure and makes it easier for your heart to pump blood throughout your body.
  • Heart Failure: When used alongside other treatments, Acupil 5mg Tablet reduces the workload on a weakened heart, improving survival rates and helping to manage symptoms like shortness of breath and fluid buildup.

Key Benefits

Taking Acupil 5mg Tablet consistently can help you feel better and protect your long-term health in several ways:

  • Reduces the Risk of Serious Cardiovascular Events: By maintaining healthy blood pressure levels, this medicine significantly lowers your long-term risk of experiencing a stroke or heart attack.
  • Improves Daily Physical Capacity: For patients managing heart failure, this medicine helps improve overall heart efficiency, allowing you to walk further and engage in daily activities with less fatigue or breathlessness.
  • Protects Long-Term Kidney Function: In certain patients, keeping blood pressure controlled with this class of medicine helps preserve kidney health over time by reducing physical pressure on the delicate blood vessels in the kidneys.

Directions for Use

  • Acupil 5mg Tablet can be taken with or without food as advised by your doctor.
  • It is recommended to take Acupil 5mg Tablet once daily or as advised by your doctor.
  • Swallow the tablet as a whole with a glass of water.
  • Do not break, chew or crush Acupil 5mg Tablet .

How Acupil 5mg Tablet Works

Acupil 5mg Tablet contains quinapril, an angiotensin-converting enzyme (ACE) inhibitor that helps lower blood pressure and reduce the workload on the heart. Acupil 5mg Tablet works by blocking the action of the angiotensin-converting enzyme (ACE), which is involved in the production of angiotensin II, a natural substance that causes blood vessels to tighten and narrow. By reducing the formation of angiotensin II, Acupil 5mg Tablet helps blood vessels relax and widen, allowing blood to flow more easily. As blood pressure decreases, the heart does not have to work as hard to pump blood throughout the body. This helps improve circulation and reduces the strain on the heart and blood vessels. Together, these actions help control high blood pressure, improve heart function, and reduce the risk of complications such as heart attack, stroke, and kidney damage.
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Alcohol

Unsafe

Do not consume alcohol while taking this medicine as it may worsen the side effects like dizziness and also increase blood pressure.

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Pregnancy

Unsafe

Acupil 5mg Tablet is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Acupil 5mg Tablet . Treatment with this medicine should be stopped as soon as a pregnancy is detected.

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Breast Feeding

Caution

Acupil 5mg Tablet is excreted in breast milk. Generally, use is not recommended. However, if you are a breastfeeding woman, consult your doctor before using Acupil 5mg Tablet .

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Driving

Unsafe

Do not drive or operate machinery while using Acupil 5mg Tablet as it may cause drowsiness. Seek medical attention if the symptoms persist longer.

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Liver

Caution

It is not known how Acupil 5mg Tablet affects patients with liver disease. However, if you have a pre-existing or a history of liver disease, inform your doctor before taking Acupil 5mg Tablet .

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Acupil 5mg Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Acupil 5mg Tablet is not recommended for use in children below 18 years of age as the safety and efficacy are not established for this age group.

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Heart

Caution

Acupil 5mg Tablet should be used with caution and under medical supervision in patients with heart problems. Therefore, please consult your doctor before using Acupil 5mg Tablet .

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Geriatrics

Caution

Acupil 5mg Tablet should be used with caution in geriatric patients due to increased risk of age-related side effects. Therefore, please consult your doctor before giving Acupil 5mg Tablet to elderly individuals.

What if I have taken an overdose of Acupil 5mg Tablet

If you take too much of this medicine, you may experience severe dizziness, fainting, or a rapid, weak heartbeat. Seek immediate emergency medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

Implementing specific daily habits can support the effectiveness of your treatment:

  • Limit your sodium intake: High amounts of salt in your diet can counteract the effects of this medicine. Aim to cook fresh meals and limit processed foods that are high in sodium.
  • Avoid potassium-based salt substitutes: This medication can raise the level of potassium in your blood. Avoid using salt alternatives that contain potassium, and consult your doctor before taking potassium supplements.
  • Stay hydrated: Dehydration can cause your blood pressure to drop too low while taking this medicine. Drink plenty of water daily, especially during hot weather or when exercising.
  • Limit alcohol consumption: Drinking alcohol can enhance the blood-pressure-lowering effect of Acupil 5mg Tablet , making you feel excessively dizzy or faint when standing up.
  • Monitor your blood pressure at home: Keep a simple daily log of your readings. Sharing this with your healthcare team helps them monitor how well the treatment is working.
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How Soon It Starts Working

The time required for Acupil 5mg Tablet to start to work: Acupil 5mg Tablet ideally shows its action within 1 hour after administration. The time for which the effects of Acupil 5mg Tablet last: The effect of Acupil 5mg Tablet lasts for 24 hours.

What if you forget to take Acupil 5mg Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a forgotten one.

Storage

•Store Acupil 5mg Tablet at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Stand up slowly: To prevent dizziness or fainting, take your time when rising from a sitting or lying position, especially when you first start taking this medicine.
  • Stop immediately if pregnant: This medicine can cause serious harm or death to an unborn baby. If you become pregnant while taking Acupil 5mg Tablet , stop taking it immediately and contact your doctor.
  • Monitor kidney function and blood count: Your doctor may schedule regular blood tests to check your kidney health and monitor your potassium levels while on this medication.
  • Watch out for a dry cough: If you develop a persistent, dry cough that does not go away, do not take over-the-counter cough medicines, as they will not help. Contact your doctor to discuss alternatives.
  • Avoid heavy machinery initially: Wait to see how this medicine affects you before driving, operating machinery, or performing tasks that require alertness.

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with Acupil 5mg Tablet :

  • Potassium supplements and potassium-sparing water pills: Taking these alongside Acupil 5mg Tablet can lead to dangerously high potassium levels in your blood.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen: These pain relievers can reduce the effectiveness of your blood pressure medicine and increase the risk of severe kidney damage.
  • Lithium: This medication can increase the levels of lithium in your body to toxic levels, requiring close monitoring by your doctor.
  • Other blood pressure medications: Taking multiple blood pressure lowering drugs together can cause your pressure to drop too low and strain your kidneys.
QuinaprilSpironolactone
Severe
QuinaprilTizanidine
Severe

Drug-Drug Interactions

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QuinaprilSpironolactone
Severe
How does the drug interact with Acupil 5mg Tablet:
Using Acupil 5mg Tablet together with spironolactone may cause hyperkalemia (increase the levels of potassium in your blood).

How to manage the interaction:
Although taking spironolactone and Acupil 5mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as weakness, confusion, numbness or tingling, and uneven heartbeat. Do not stop using any medications without consulting doctor.
QuinaprilTizanidine
Severe
How does the drug interact with Acupil 5mg Tablet:
Combining Tizanidine and Acupil 5mg Tablet can lower your blood pressure.

How to manage the interaction:
Taking Tizanidine and Acupil 5mg Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate, contact your doctor immediately. Avoid driving or operating hazardous machinery until you know how the medications affect you, use caution when getting up from a sitting or lying position, and do not discontinue any medications without consulting your doctor.
QuinaprilAmiloride
Severe
How does the drug interact with Acupil 5mg Tablet:
Taking Amiloride with Acupil 5mg Tablet may cause a rise in potassium levels in blood.

How to manage the interaction:
Although taking amiloride and Acupil 5mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience symptoms including fatigue, disorientation, numbness or tingling, and irregular heartbeats. Do not discontinue any medications without a doctor's advice.
QuinaprilTrimethoprim
Severe
How does the drug interact with Acupil 5mg Tablet:
Taking Trimethoprim with Acupil 5mg Tablet can cause high levels of potassium in the blood.

How to manage the interaction:
Although there is a interaction between Trimethoprim and Acupil 5mg Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs like feeling unwell, feeling dehydrated it's best to contact your doctor right away. Do not stop using any medications without a doctor's advice.
QuinaprilAllopurinol
Severe
How does the drug interact with Acupil 5mg Tablet:
Co-administration of Allopurinol with Acupil 5mg Tablet may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Allopurinol and Acupil 5mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also, let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue any medications without consulting a doctor.
QuinaprilTelmisartan
Severe
How does the drug interact with Acupil 5mg Tablet:
Taking Acupil 5mg Tablet with telmisartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and high blood potassium.

How to manage the interaction:
Although there is a possible interaction, telmisartan can be taken with Acupil 5mg Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of high potassium, such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Maintain adequate fluid intake during treatment with these medications. Do not discontinue the medications without consulting a doctor.
QuinaprilValsartan
Severe
How does the drug interact with Acupil 5mg Tablet:
The use of Acupil 5mg Tablet and Valsartan may increase the risk of side effects (low blood pressure, kidney function impairment, and hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Acupil 5mg Tablet together with Valsartan may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat, contact a doctor. Do not discontinue any medication without consulting a doctor.
QuinaprilAzilsartan medoxomil
Severe
How does the drug interact with Acupil 5mg Tablet:
Taking Azilsartan medoxomil with Acupil 5mg Tablet may cause low blood pressure, kidney function impairment, and increased potassium levels in the blood.

How to manage the interaction:
Although taking Azilsartan medoxomil with Acupil 5mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Consult a doctor if you experience vomiting, weakness, tingling in your hands and feet, or palpitations. Do not discontinue any medications without a doctor's advice.
QuinaprilLosartan
Severe
How does the drug interact with Acupil 5mg Tablet:
Coadministration of Losartan with Acupil 5mg Tablet can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking Losartan with Acupil 5mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip

The following foods or dietary products may affect Acupil 5mg Tablet :

  • High-fat meals: Eating a meal very high in fat can decrease the absorption of Acupil 5mg Tablet , reducing its efficacy. Try to take your medicine consistently regarding food.
  • Salt substitutes: Many commercial salt substitutes contain potassium chloride, which can interact with this medicine to cause high blood potassium levels.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Acupil 5mg Tablet is used to treat Hypertension.
Acupil 5mg Tablet contains Quinapril, which belongs to the Angiotensin-converting enzyme (ACE) inhibitors class. It works by reducing the production of certain substances that cause an increase in blood pressure. This allows the blood to flow more smoothly and makes the heart more efficient at pumping blood throughout the body.
No. Do not stop taking Acupil 5mg Tablet without consulting your doctor, even if you feel well or your blood pressure is normal. High blood pressure often has no symptoms, and stopping treatment suddenly may cause your blood pressure to rise again, increasing the risk of heart attack or stroke. Continue taking the medicine as prescribed and speak with your doctor before making any changes to your treatment.
It is advised not to miss any dose of Acupil 5mg Tablet . However, if you forget to take a dose of Acupil 5mg Tablet , take it as soon as you remember unless it is time for your next dose. Do not double the dose, as it may lead to low blood pressure.
Acupil 5mg Tablet should be taken as advised by your doctor. Acupil 5mg Tablet can be taken with or without food, but taking it at the same time daily ensures consistent absorption and better results. Always follow your doctor’s instructions.
Acupil 5mg Tablet causes side effects such as headache, diarrhoea, difficulty breathing, dizziness, nausea, cough, drowsiness, loss of appetite, tiredness, and chest pain. Most of these are temporary and do not require any medical attention, as they will gradually reduce over time. Please, contact a doctor if these persist for longer durations.
You are not recommended to stop taking Acupil 5mg Tablet even if you feel better, as you may experience severe complications such as raised blood pressure and chances of stroke or heart attack. However, contact a doctor if you have any concerns.
Acupil 5mg Tablet may make you feel dizzy, particularly when standing up quickly. To manage this, you are recommended to avoid alcohol while taking Acupil 5mg Tablet , as it may cause excessive dizziness. If the dizziness continues or becomes more severe, contact your healthcare provider to assess your treatment and make any necessary adjustments.
While taking Acupil 5mg Tablet , maintain a healthy weight with a BMI of 19.5-24.9. Exercise regularly for at least 30 minutes most days. Eat a diet rich in whole grains, fruits, vegetables, and low-fat dairy and try to limit salt intake to 2300 mg per day. Avoid smoking and alcohol, manage stress, and monitor your blood pressure regularly. Consult your doctor, if you have any concerns.
Acupil 5mg Tablet may increase potassium levels, particularly in individuals with uncontrolled diabetes, kidney issues, dehydration, or those using potassium supplements or other medications that raise potassium. If you have any of these conditions while taking Acupil 5mg Tablet , it is important to monitor potassium levels through regular blood tests.
There is no evidence to recommend that Acupil 5mg Tablet affects fertility. However, if you are planning to become pregnant, consult your doctor, as it is not recommended during pregnancy.
A persistent dry cough is a known side effect of Acupil 5mg Tablet . It occurs because the medicine increases the level of a natural substance called bradykinin, which can irritate the airways. Although the cough is usually harmless, it can be troublesome. Do not stop taking Acupil 5mg Tablet on your own. If the cough persists or becomes bothersome, consult your doctor, who may recommend an alternative treatment if necessary.
No, you should not take Acupil 5mg Tablet during pregnancy. This medicine can cause severe harm or fatal injury to an unborn baby. If you suspect you are pregnant, stop taking the medication and talk to your doctor immediately.
It is best to limit or avoid alcohol while taking this medicine. Alcohol can enhance the blood-pressure-lowering effect of Acupil 5mg Tablet , which may cause you to experience severe dizziness, lightheadedness, or fainting. Talk to your doctor about safe alcohol consumption.
You should avoid using salt substitutes that contain potassium, as well as high-potassium supplements, because this medication can naturally increase potassium levels in your body. It is also wise to avoid eating extremely high-fat meals right when you take your dose, as they can lower the drug's absorption. Talk to your doctor or pharmacist for personalized dietary advice.
This is a medical emergency known as angioedema. Stop taking the medicine immediately and seek emergency medical care. Do not take this medication again if you experience this reaction. Talk to your doctor to find a safer alternative.
Yes, your doctor will likely recommend periodic blood tests to monitor your kidney function and check the potassium levels in your blood. These routine checks ensure that the medicine remains safe for you to use long-term. Talk to your doctor to set up a monitoring schedule.

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Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18Th Floor , Plot No. C-70, €˜G’ Block , Bandra Kurla Complex, Bandra East , Mumbai €“ 400051
Other Info - ACU0032
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