I am diabetic and currently taking Gluconorm-G2 in the morning and Glycomet SR 500 mg in the evening. After taking the evening tablet, I experience stomach upset and gas problems. Could this be a side effect of the medicine, and what can be done to reduce these symptoms?

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I am diabetic and currently taking Gluconorm-G2 in the morning and Glycomet SR 500 mg in the evening. After taking the evening tablet, I experience stomach upset and gas problems. Could this be a side effect of the medicine, and what can be done to reduce these symptoms?

Asked by Male, 50 · 12 days ago

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

12 days ago

Yes, stomach upset and gas can be side effects of Glycomet SR. This is a very common medicine for diabetes, and in many people it can cause symptoms like acidity, bloating, gas, loose motions, or stomach discomfort, especially in the beginning or when the dose is increased. The good thing is that these side effects often reduce over time as the body gets used to the medicine. To reduce these symptoms, it usually helps to take the tablet after food (not on an empty stomach) and preferably after the evening meal as advised. Eating smaller, lighter meals in the evening and avoiding very oily, spicy, or heavy foods can also reduce gas and discomfort. Drinking enough water and walking for 10-15 minutes after meals may help digestion. Some patients feel better if the dose is adjusted or if the timing is changed, but this should only be done by your doctor. In some cases, doctors may switch to a different formulation or adjust the dose if the stomach problem continues. Do not stop your diabetes medicines on your own, because good sugar control is very important. If the gas, pain, or loose motions are persistent, severe, or affecting your daily life, you should consult your doctor. They may check whether the dose is suitable for you or rule out other causes like acidity, diet issues, or intestinal sensitivity. With proper adjustment, most people are able to continue the medicine without long-term stomach problems.

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🩺 Side Effects Explanation

Metformin often causes gastrointestinal issues such as indigestion, stomach ache, gas, and sometimes diarrhea, especially when starting or increasing the dose.

🩺 Timing and Dosage Considerations

Taking metformin with meals—ideally during or right after food intake—can help reduce stomach discomfort. Using the slow-release (SR) formulation like Glycomet SR is already a good step, but timing and dose adjustments might still be needed.

🏥 Management Strategies

Take your medication with or immediately after food.
Avoid large, fatty meals that can worsen gas.
Discuss with your doctor about possibly starting at a lower dose and gradually increasing it.
Consider if switching entirely to a slow-release formulation could improve symptoms.

⚠️ When to Consult a Doctor

If stomach upset and gas persist beyond a couple of weeks, worsen, or are accompanied by severe abdominal pain, vomiting, or signs of lactic acidosis (e.g., muscle pain, difficulty breathing), please see your diabetologist promptly.

Consult your diabetologist to review your medication regimen and ensure that symptoms are managed safely and effectively.

Answered 12 days ago