Antifungal tablets are sometimes prescribed for severe dandruff or seborrheic dermatitis when medicated shampoos alone are not giving enough relief. These medicines help reduce the growth of fungus on the scalp that can contribute to flaking, itching, and irritation. If your dermatologist has prescribed the tablet after examining you, it is generally safe to take it as directed. However, like all medicines, antifungal tablets can have some side effects. The most common one is nausea. In rare cases, they may affect the liver, so doctors are usually more careful in people who already have liver disease or those taking many other medicines. It is important not to take these tablets for longer than advised and to avoid alcohol while using them, as that may increase the strain on the liver. Continue using the prescribed anti-dandruff shampoo regularly, keep your scalp clean, avoid excessive oil application, and try to reduce stress, as dandruff can worsen with stress and lack of sleep. If you notice severe itching, yellowing of the eyes, dark urine, persistent vomiting, or unusual tiredness after starting the medicine, contact your doctor promptly. Overall, when taken under proper medical supervision, antifungal tablets are commonly used and can be effective for stubborn dandruff problems.