Your MRI findings show common, wear-and-tear changes at the C5-C6 level of your neck, which can irritate nearby nerves and cause shoulder pain. To manage this safely, several generic medications can help: 1. Pain and Inflammation: Nonsteroidal anti-inflammatory drugs (NSAIDs) like naproxen or ibuprofen. 2. Muscle Spasms: Muscle relaxants such as cyclobenzaprine. 3. Nerve Pain: For shooting pain or tingling, nerve-calming medications like gabapentin or pregabalin are highly effective. Please consult your doctor to determine the best prescription for your specific health profile. Combining these medications with targeted physical therapy often provides the most effective, long-term relief.