The most commonly recommended medications for Obsessive-Compulsive Disorder (OCD) are Selective Serotonin Reuptake Inhibitors (SSRIs), such as sertraline, fluoxetine, or fluvoxamine. Another effective option is clomipramine. These medications help balance brain chemicals to reduce obsessive thoughts and compulsions. It typically takes 8 to 12 weeks to start seeing significant improvement. Once the medication is working well, treatment is generally recommended to continue for at least 12 to 24 months to prevent symptoms from returning. Some individuals may benefit from longer-term treatment. Your doctor will work with you to find the safest and most comfortable timeline for your recovery.