Being HLA-B27 positive with long-standing back pain that started in the sacroiliac area and has spread to the spine suggests a type of inflammatory back condition, where regular treatment is often needed to control pain and stiffness. Etoshine-90 belongs to a group of medicines that reduce inflammation and pain, and it is commonly used for this kind of problem. While it can be taken regularly for better symptom control, it should not be continued long-term without medical supervision, because prolonged use may affect the stomach, kidneys, heart, or blood pressure in some people. Doctors usually prescribe it at the lowest effective dose for the shortest duration needed and may monitor you with periodic check-ups and tests. If your pain is frequent or severe, it is important to consult a rheumatologist, who may suggest safer long-term options such as specific anti-inflammatory treatments, exercises, posture correction, and physiotherapy to manage the condition more effectively. The goal is not just temporary relief but long-term control with minimal side effects.