While many supplements claim to boost metabolism, there is no magic pill. Over-the-counter options like caffeine or green tea extract offer only minor, temporary effects and can cause side effects. If a medical condition like an underactive thyroid is slowing your metabolism, a doctor may prescribe levothyroxine. For weight management, prescription options like liraglutide or phentermine can be discussed with your physician. Ultimately, building muscle through strength training and staying active are the most effective ways to naturally increase your metabolic rate. Please consult your doctor before starting any new supplement to ensure it is safe for you.