It is generally advised to avoid additional vitamin A supplements while taking isotretinoin like Deriva I-16 mg due to the risk of excessive vitamin A levels and related side effects. Since your collagen supplement contains B-complex vitamins but no vitamin A, it is likely safe to continue, but you should still confirm with your doctor.

🩺 Safety Concerns with Isotretinoin and Supplements

• Isotretinoin is a powerful vitamin A derivative, and extra vitamin A intake can lead to toxicity (hypervitaminosis A).
• Collagen supplements with B-complex vitamins typically do not contain vitamin A, reducing risk of interaction.
• Avoid any supplements or multivitamins with added vitamin A during isotretinoin treatment without medical approval.

🩺 Recommendations

• Continue your collagen supplement only if the label confirms no vitamin A content.
• Inform your dermatologist (skin specialist) about all supplements you take.
• Follow your doctor’s advice about routine tests and monitoring during isotretinoin therapy.

If you want, I can explain isotretinoin’s vitamin A interaction risks in more detail. Always consult your dermatologist before starting or continuing any supplements while on isotretinoin.