Chronic myeloid leukaemia (CML) is a type of blood cancer that usually develops slowly and affects the white blood cells. Treatment has improved greatly over the years, and many people with CML are able to live for long periods with good disease control when treatment is started early and taken regularly. The exact treatment depends on age, overall health, blood reports, disease stage, and response to therapy. The main treatment for CML commonly includes targeted medicines called tyrosine kinase inhibitors, which help control the abnormal blood cells and slow disease progression. Regular blood tests and monitoring are very important because treatment response needs to be checked over time. In some cases, chemotherapy, immunotherapy, or bone marrow transplant may be considered if the disease becomes resistant or more aggressive. Proper nutrition, hydration, infection prevention, rest, and emotional support are also important during treatment. Avoid stopping medicines without medical advice because regular treatment is essential for long-term control. Consult a doctor regularly and seek urgent medical attention if there is severe weakness, fever, unusual bleeding, breathlessness, rapid weight loss, or repeated infections during treatment.