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  5. My relative has been hospitalised for two weeks with pleural effusion, ascites, and bowel distension. Her CA-125 tumour marker level is extremely high at 945 U/mL, and she has been referred to a gynaecologist who is considering a hysterectomy or ovary removal. Does this high CA-125 level indicate a chance of ovarian cancer, and what are the recommended next steps, medical treatments, or surgical options?

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My relative has been hospitalised for two weeks with pleural effusion, ascites, and bowel distension. Her CA-125 tumour marker level is extremely high at 945 U/mL, and she has been referred to a gynaecologist who is considering a hysterectomy or ovary removal. Does this high CA-125 level indicate a chance of ovarian cancer, and what are the recommended next steps, medical treatments, or surgical options?

Asked by Female, 29 · 3 days ago

A CA-125 level of 945 U/mL is elevated and raises the possibility of ovarian cancer, especially alongside ascites and pleural effusion. However, it is not a definitive diagnosis, as benign inflammation can also increase this marker. The next step is a thorough evaluation by a gynecologic oncologist, likely including a CT scan. If a tumour is suspected, surgery (such as removing the ovaries and uterus) is the standard approach to both confirm the diagnosis and remove the disease. Depending on the surgical findings, chemotherapy using medications like carboplatin and paclitaxel may follow. Please discuss these findings closely with her specialist team.
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My relative has been hospitalised for two weeks with pleural effusion, ascites, and bowel distension. Her CA-125 tumour marker level is extremely high at 945 U/mL, and she has been referred to a gynaecologist who is considering a hysterectomy or ovary removal. Does this high CA-125 level indicate a chance of ovarian cancer, and what are the recommended next steps, medical treatments, or surgical options?

Answered 3 days ago

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