An elevated Total Count (WBC) and ESR usually indicate that your body is actively fighting an infection or dealing with temporary inflammation. These are general markers, not specific diseases, so there is no single medication to lower them directly. Instead, treatment targets the underlying cause. For instance, a bacterial infection may require generic antibiotics (like amoxicillin), while inflammation might be managed with anti-inflammatory medications (like ibuprofen). Please do not worry, as these levels commonly return to normal once the root cause is resolved. I highly recommend consulting your doctor for a proper diagnosis and targeted treatment plan rather than self-medicating.