Yes, you can use Betadine 2% Mint Gargle (povidone-iodine) to help relieve a sore throat. Gargling with it may reduce germs in your mouth and throat, easing irritation and coughing. Make sure to drink plenty of fluids, rest your voice, and try warm saltwater gargles as a gentle alternative. Consult a doctor if your symptoms worsen or persist for more than a week.