At 45, these symptoms are often seen during perimenopause, when natural hormonal changes can affect memory, mood, weight, and menstrual cycles. But other important causes also need to be considered, such as thyroid imbalance, stress, poor sleep, vitamin B12 or iron deficiency, anxiety or depression, or metabolic conditions. Since several issues are occurring simultaneously, it’s important not to assume a single cause without proper testing. A doctor or gynaecologist can evaluate your condition and may suggest tests like thyroid function, blood sugar, haemoglobin, and relevant vitamin or hormone levels. Professional evaluation is essential to identify the exact cause and guide the right treatment.